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DNA sequencing has become increasingly efficient over the years, resulting in an enormous increase in the amount of data gener­ ated. In recent years, the focus of sequencing has shifted, from being the endpoint of a project, to being a starting point. This is especially true for such major initiatives as the human genome project, where vast tracts of DNA of unknown function are sequenced. This sheer volume of available data makes advanced computer methods essen­ tial to analysis, and a familiarity with computers and sequence analy­ sis software a vital requirement for the researcher involved with DNA sequencing. Even for nonsequencers, a familiarity with sequence analysis software can be important. For instance, gene sequences already present in the databases can be extremely useful in the design of cloning and genetic manipulation experiments. This two-part work on Computer Analysis of Sequence Data is designed to be a practical aid to the researcher who uses computers for the acquisition, storage, or analysis of nucleic acid (and/or pro­ tein) sequences. Each chapter is written such that a competent scien­ tist with basic computer literacy can carry out the procedure successfully at the first attempt by simply following the detailed prac­ tical instructions that have been described by the author. A Notes section, which is included at the end of each chapter, provides advice on overcoming the common problems and pitfalls sometimes encoun­ tered by users of the sequence analysis software.

Amino acid sequence --- Nucleotide sequence --- Data processing. --- 577.212.3 --- 57.088.5 --- 57.081.2 --- 57.081.2 Automation of biological experiments --- Automation of biological experiments --- 577.212.3 Nucleic acid base and sequence compositon. Experimental deciphering of genetic code. --- Nucleic acid base and sequence compositon. Experimental deciphering of genetic code. --- Methods and techniques for studying structures and properties of biological molecules --- Séquence des acides aminés --- Séquence nucléotidique --- Data processing --- Informatique --- Amino acid sequence analysis --- Analysis, Amino acid sequence --- Peptide sequence --- Peptide sequencing --- Protein sequence --- Protein sequencing --- Sequence, Amino acid --- Amino acids --- Proteins --- Sequence alignment (Bioinformatics) --- Analysis --- Cytology. --- Cell Biology. --- Cell biology --- Cellular biology --- Biology --- Cells --- Cytologists

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Science --- Scientific apparatus and instruments --- Computer graphics --- Infographie --- Experiments --- Data processing --- Computer simulation --- LabVIEW --- 681.3*J2 --- 681.3*D32 --- 57.081.2 --- -Scientific apparatus and instruments --- -Computer graphics --- 681.3*I63 --- Automatic drafting --- Graphic data processing --- Graphics, Computer --- Computer art --- Graphic arts --- Electronic data processing --- Engineering graphics --- Image processing --- Apparatus, Scientific --- Instruments, Scientific --- Scientific instruments --- Research --- Natural science --- Science of science --- Sciences --- Physical sciences and engineering (Computer applications) --- language classifications: applicative languages; data-flow languages; design languages; extensible languages; macro and assembly languages; nonprocedural languages; specialized application and very high-level languages (Programminglanguages) --- Automation of biological experiments --- -Data processing --- Applications (Simulation and modeling) --- Digital techniques --- Instruments --- Equipment and supplies --- 681.3*I63 Applications (Simulation and modeling) --- 57.081.2 Automation of biological experiments --- 681.3*D32 language classifications: applicative languages; data-flow languages; design languages; extensible languages; macro and assembly languages; nonprocedural languages; specialized application and very high-level languages (Programminglanguages) --- 681.3*J2 Physical sciences and engineering (Computer applications) --- Experiments&delete& --- LabVIEW. --- Lab VIEW --- Natural sciences --- Data processing. --- Science - Experiments - Data processing --- Scientific apparatus and instruments - Computer simulation --- Automatisering