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Brucellosis, caused by the facultative intracellular bacteria Brucella species, is one the most prevalent zoonosis worldwide. • The articles described in this book report several aspects of host-Brucella interactions. • The findings described here will help to advance in the comprehension of bacterial pathogenesis and contribute to the future development of drugs or vaccines to control brucellosis.

Research & information: general --- Recombinant vaccine --- divalent vaccine --- brucellosis --- Omp25 --- L7/L12 --- Brucella abortus 544 --- ST2 receptor --- Brucella abortus --- oral infection --- human endometrial cells --- internalization --- intracellular replication --- decidualization --- chemokines --- macrophages --- Brucella --- HSC --- MHC --- IL-10 --- cell cycle --- (p)ppGpp --- rsh --- neurobrucellosis --- platelets --- brain microvascular endothelial cells --- endothelial cells --- adhesins --- Ig-like domain --- monomeric autotransporters --- trimeric autotransporters --- extracellular matrix --- polar localization --- virulence factors --- vaccine candidates --- fibronectin --- canonical inflammasome --- non-canonical inflammasome --- NLR --- pyroptosis --- ASC --- caspase-11 --- caspase-1 --- IL-1β --- gDNA --- replication niche --- reservoir --- persistence --- survival --- chronic infection --- n/a

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• Reference Manager
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Brucellosis, caused by the facultative intracellular bacteria Brucella species, is one the most prevalent zoonosis worldwide. • The articles described in this book report several aspects of host-Brucella interactions. • The findings described here will help to advance in the comprehension of bacterial pathogenesis and contribute to the future development of drugs or vaccines to control brucellosis.

Recombinant vaccine --- divalent vaccine --- brucellosis --- Omp25 --- L7/L12 --- Brucella abortus 544 --- ST2 receptor --- Brucella abortus --- oral infection --- human endometrial cells --- internalization --- intracellular replication --- decidualization --- chemokines --- macrophages --- Brucella --- HSC --- MHC --- IL-10 --- cell cycle --- (p)ppGpp --- rsh --- neurobrucellosis --- platelets --- brain microvascular endothelial cells --- endothelial cells --- adhesins --- Ig-like domain --- monomeric autotransporters --- trimeric autotransporters --- extracellular matrix --- polar localization --- virulence factors --- vaccine candidates --- fibronectin --- canonical inflammasome --- non-canonical inflammasome --- NLR --- pyroptosis --- ASC --- caspase-11 --- caspase-1 --- IL-1β --- gDNA --- replication niche --- reservoir --- persistence --- survival --- chronic infection --- n/a

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Biosensors are analytical devices capable of providing quantitative or semi-quantitative information by using a biological recognition element and a transducer. Depending upon the nature of the recognition element, different surface sensitive techniques can be applied to monitor these molecular interactions. In order to increase sensitivities and to lower detection limits down to even individual molecules, nanomaterials are promising candidates. This is possible due to the potential to immobilize more bioreceptor units at reduced volumes and their ability to act as transduction elements by themselves. Among such nanomaterials, gold nanoparticles, quantum dots, polymer nanoparticles, carbon nanotubes, nanodiamonds, and graphene are intensively studied. Biosensors provide rapid, real-time, accurate, and reliable information about the analyte under investigation and have been envisioned in a wide range of analytical applications, including medicine, food safety, bioprocessing, environmental/industrial monitoring, and electronics. A variety of biosensors, such as optical, spectroscopic, molecular, thermal, and piezoelectric, have been studied and applied in countless fields. In this book, examples of spectroscopic and optical biosensors and immunoassays are presented. Furthermore, two comprehensive reviews on optical biosensors are included

brain tumour diagnosis --- classification --- forward feature extraction algorithm --- intraoperative use --- Raman spectroscopy --- Raman probe --- SERS on ultrafine solid supports --- glass coverslips --- BPE --- thiol-DNA probe --- annealed gold nanostructures --- Brucella abortus --- Brucella melitensis --- Brucella suis --- optical fiber --- biosensor --- nucleotide probe --- light transmission --- diagnosis --- silver nanoparticles --- synthesis --- coating --- alloy --- core@shell --- LSPR --- biosensors --- water pollution --- environmental water --- drinking water --- milk --- heavy metal ions --- detection limits --- optical spectroscopy --- proteins --- functional nucleic acids --- flow-through immunoassay --- lateral flow immunoassay --- food allergen --- multiplex --- smartphone analysis --- carbon nanoparticle labeling

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Biosensors are analytical devices capable of providing quantitative or semi-quantitative information by using a biological recognition element and a transducer. Depending upon the nature of the recognition element, different surface sensitive techniques can be applied to monitor these molecular interactions. In order to increase sensitivities and to lower detection limits down to even individual molecules, nanomaterials are promising candidates. This is possible due to the potential to immobilize more bioreceptor units at reduced volumes and their ability to act as transduction elements by themselves. Among such nanomaterials, gold nanoparticles, quantum dots, polymer nanoparticles, carbon nanotubes, nanodiamonds, and graphene are intensively studied. Biosensors provide rapid, real-time, accurate, and reliable information about the analyte under investigation and have been envisioned in a wide range of analytical applications, including medicine, food safety, bioprocessing, environmental/industrial monitoring, and electronics. A variety of biosensors, such as optical, spectroscopic, molecular, thermal, and piezoelectric, have been studied and applied in countless fields. In this book, examples of spectroscopic and optical biosensors and immunoassays are presented. Furthermore, two comprehensive reviews on optical biosensors are included

Research & information: general --- brain tumour diagnosis --- classification --- forward feature extraction algorithm --- intraoperative use --- Raman spectroscopy --- Raman probe --- SERS on ultrafine solid supports --- glass coverslips --- BPE --- thiol-DNA probe --- annealed gold nanostructures --- Brucella abortus --- Brucella melitensis --- Brucella suis --- optical fiber --- biosensor --- nucleotide probe --- light transmission --- diagnosis --- silver nanoparticles --- synthesis --- coating --- alloy --- core@shell --- LSPR --- biosensors --- water pollution --- environmental water --- drinking water --- milk --- heavy metal ions --- detection limits --- optical spectroscopy --- proteins --- functional nucleic acids --- flow-through immunoassay --- lateral flow immunoassay --- food allergen --- multiplex --- smartphone analysis --- carbon nanoparticle labeling