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Antigens, CD. --- B-Lymphocytes. --- Cluster of Differentiation Antigens --- Cluster of Differentiation Markers --- Differentiation Antigens, Leukocyte, Human --- Leukocyte Differentiation Antigens, Human --- CD Antigens --- B cells --- CD antigens --- Antigens, CD --- B-Lymphocytes --- Congresses. --- congresses. --- B-Cells --- Bursa-Dependent Lymphocytes --- B Cells --- B Lymphocytes --- B-Cell --- B-Lymphocyte --- Bursa Dependent Lymphocytes --- Bursa-Dependent Lymphocyte --- Lymphocyte, Bursa-Dependent --- Lymphocytes, Bursa-Dependent --- CD glycoproteins --- CD molecules --- CD receptors --- CD surface immunoglobulin ligands --- Differentiation antigens, Human leukocyte --- Human leukocyte differentiation antigens --- Leukocyte differentiation antigens, Human --- Cell surface antigens --- Fc receptors --- Glycoproteins --- B lymphocytes --- Bone marrow derived cells --- Bursa equivalent cells --- Antigen presenting cells --- Lymphocytes --- Congresses --- B cells - Congresses. --- CD antigens - Congresses. --- B Cell --- B Lymphocyte --- CD Antigen --- Cluster of Differentiation Antigen --- Cluster of Differentiation Marker --- Antigen Cluster, Differentiation --- Antigen, CD --- Differentiation Antigen Cluster --- Differentiation Marker Cluster --- Marker Cluster, Differentiation --- B-Cells, Lymphocyte --- B Cells, Lymphocyte --- B-Cell, Lymphocyte --- Lymphocyte B-Cell --- Lymphocyte B-Cells

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For decades, T cells were thought to solely respond to protein-derived antigens. However, the discovery of the CD1 antigen presenting system shows how antigen presenting cells can display lipid antigens to T cells. Crystal structures show that CD1 proteins accomplish this function by inserting lipids into a hydrophobic groove on the distal surface of the protein, forming CD1-lipid complexes that act as ligands for T cell receptors. CD1-reactive T cells with conserved (NK T cells) or diverse T cell receptors possess cytokine secretion and other effector mechanisms that influence many aspects of immune response. There is increasing evidence that the CD1 system has been conserved throughout mammalian evolution and is capable of presenting structurally diverse diacyglycerol, sphingolipid, polyisoprenol and lipopeptide antigens. These features of CD1 antigen presentation systems now point to a new and expanded view of the natural function of ab T cells, which involves surveillance of both the protein and lipid components of target cells. Further, cellular systems that were previously considered to have functions in lipid metabolism can now be studied in context of their immunological functions. This volume provides a comprehensive discussion of these basic aspects of CD1 biology and summarizes the most recent research into the role of CD1 in infectious, autoimmune, allergic and neoplastic disease.

CD antigens. --- T cells --- Receptors. --- T cell receptors --- T lymphocyte antigen receptors --- Cell receptors --- Antigens, CD --- CD glycoproteins --- CD molecules --- CD receptors --- CD surface immunoglobulin ligands --- Differentiation antigens, Human leukocyte --- Human leukocyte differentiation antigens --- Leukocyte differentiation antigens, Human --- Cell surface antigens --- Fc receptors --- Glycoproteins --- Immunology. --- Immunobiology --- Life sciences --- Serology

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A volume in the popular FactsBook Series, the First Edition of The Leucocyte Antigen FactsBook was hugely successful. The new Second Edition has been completely revised, updated, and expanded by 65% to include new findings and up-to-date key references. The introductory chapters have also been updated, especially in terms of nomenclature, the role of the World Wide Web, and new structural data. The Leucocyte Antigen FactsBook, Second Edition contains more than 200 entries, with approximately 70 new entries, on all the molecules specifically expressed in the surface of cells of the haematopoietic system, including all characterized CD antigens, antigen receptors, MHC antigens, adhesion molecules, and cytokine receptors. This FactsBook will be of enormous value to immunologists, cell biologists, biochemists, and endocrinologists.

CD antigens --- HLA histocompatibility antigens --- Leucocytes --- Antigens, CD --- CD glycoproteins --- CD molecules --- CD receptors --- CD surface immunoglobulin ligands --- Differentiation antigens, Human leukocyte --- Human leukocyte differentiation antigens --- Leukocyte differentiation antigens, Human --- Leukocytes --- White blood cells --- White cells --- HL-A histocompatibility antigens --- HLA antigens --- HLA transplantation antigens --- Human leukocyte antigens --- Transplantation antigens, Human --- Cell surface antigens --- Fc receptors --- Glycoproteins --- Blood cells --- Killer cells --- Histocompatibility antigens --- Major histocompatibility complex --- Handbooks, manuals, etc

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Immunology. Immunopathology --- HLA histocompatibility antigens --- Antigens, CD --- Cell Adhesion Molecules --- Handbooks, manuals, etc --- Antigens, CD. --- Cell Adhesion Molecules. --- -616-097 --- 577.27 --- HL-A histocompatibility antigens --- HLA antigens --- HLA transplantation antigens --- Human leukocyte antigens --- Transplantation antigens, Human --- Histocompatibility antigens --- Major histocompatibility complex --- Saccharide Mediated Cell Adhesion Molecules --- Intercellular Adhesion Molecules --- Leukocyte Adhesion Molecules --- Saccharide-Mediated Cell Adhesion Molecules --- Adhesion Molecules, Cell --- Adhesion Molecules, Intercellular --- Adhesion Molecules, Leukocyte --- Molecules, Cell Adhesion --- Molecules, Intercellular Adhesion --- Molecules, Leukocyte Adhesion --- Integrins --- Cluster of Differentiation Antigens --- Cluster of Differentiation Markers --- Differentiation Antigens, Leukocyte, Human --- Leukocyte Differentiation Antigens, Human --- CD Antigens --- Antigens. Antibodies --- Molecular bases of immunity. Molecular immunology --- Antigens. --- CD antigens --- HLA Antigens --- Handbooks, manuals, etc. --- handbooks. --- 577.27 Molecular bases of immunity. Molecular immunology --- 616-097 Antigens. Antibodies --- Antigens, cd --- Cd antigens --- Hla antigens --- Hla histocompatibility antigens --- Handbooks. --- 616-097 --- CD glycoproteins --- CD molecules --- CD receptors --- CD surface immunoglobulin ligands --- Differentiation antigens, Human leukocyte --- Human leukocyte differentiation antigens --- Leukocyte differentiation antigens, Human --- Cell surface antigens --- Fc receptors --- Glycoproteins --- LEUCOCYTES --- Monograph --- Leucocytes. --- Leukocytes --- White blood cells --- White cells --- Blood cells --- Killer cells --- Cell Adhesion Molecule --- Intercellular Adhesion Molecule --- Leukocyte Adhesion Molecule --- Adhesion Molecule, Cell --- Adhesion Molecule, Intercellular --- Adhesion Molecule, Leukocyte --- Molecule, Cell Adhesion --- Molecule, Intercellular Adhesion --- Molecule, Leukocyte Adhesion --- CD Antigen --- Cluster of Differentiation Antigen --- Cluster of Differentiation Marker --- Antigen Cluster, Differentiation --- Antigen, CD --- Differentiation Antigen Cluster --- Differentiation Marker Cluster --- Marker Cluster, Differentiation

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Fas Signaling is focused on the signaling mechanisms and biology of the prototypic death receptor Fas, also called CD95 or APO-1. The chapters of this book cover, besides the well recognized apoptosis-related functions of Fas, its emerging role as a proinflammatory cytokine and as an inducer of alternative forms of cell death. Fas Signaling aims to provide the reader with an up-to-date survey of the various aspects of Fas biology and the open questions of the field are addressed. This title is intended for Ph.D and post-doctoral students starting to work in the field, but is also useful for everyone with an interest in the biology of this exciting molecule.

CD antigens. --- Cellular signal transduction. --- Cellular information transduction --- Information transduction, Cellular --- Signal transduction, Cellular --- Bioenergetics --- Cellular control mechanisms --- Information theory in biology --- Antigens, CD --- CD glycoproteins --- CD molecules --- CD receptors --- CD surface immunoglobulin ligands --- Differentiation antigens, Human leukocyte --- Human leukocyte differentiation antigens --- Leukocyte differentiation antigens, Human --- Cell surface antigens --- Fc receptors --- Glycoproteins --- Immunology. --- Medicine. --- Oncology  . --- Molecular Medicine. --- Oncology. --- Tumors --- Immunobiology --- Life sciences --- Serology --- Clinical sciences --- Medical profession --- Human biology --- Medical sciences --- Pathology --- Physicians --- Health Workforce --- Molecular biology. --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology