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This volume is a practical guide of theranostics using intraoperative fluorescence imaging technology, as an all-out effort by the Japanese Society for Fluorescence Guided Surgery. It describes the various approaches the technique is being used such as vascular imaging, identification of lymphatic vessels by intratissue injection, lymph node imaging, and imaging for identification of anatomical structures. The book is organized into three major parts and the first one delivers the basics, introducing the use of the technology in clinical settings and initial setups. Next comes the description of clinical applications where chapters illustrate perfusion assessment, cancer localization, anatomy visualization, and lymph nodes/ducts mapping. Each chapter is devoted to the specific surgical field and disease areas, presenting images and videos of case studies. The last part presents some upcoming techniques for treatments. The Editor and the authors wish the ideas presented here will be hints to bridge the knowledge between surgeons and basic researchers for further innovation and practicality. It is important to stay up-to-date since intraoperative fluorescence imaging has been applied to clinical settings in various surgical fields and at the same time, novel techniques improving the efficacy of the technology have also been developed actively. Fluorescence-Guided Surgery – From Lab to Operation Room is recommended for surgeons, operating nurses, medical experts, basic researchers and, industry engineers worldwide beyond boundaries of specialties. Edited and written by experts of The Japanese Society for Fluorescence-Guided Surgery, those who are the founders of the technology, it describes the accurate development history and cutting-edge techniques based on the knowledge accumulated over the years. This is a translated version of the book originally published in Japanese language. This has been facilitated using machine translation (by the service DeepL.com) followed by authors revising, editing and verifying the translated manuscript.

Surgery. --- Endoscopic surgery. --- Cancer --- Oncology. --- Diseases. --- Anatomy. --- Minimally Invasive Surgery. --- Cancer Imaging. --- Imaging. --- Computer-assisted surgery.

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Thepastdecadehasseendramaticadvances inurologyandimaging. Thesechangesareevident in improvements in laparoscopic surgery as well as in the emergence of multidetector CT, with multiplanar reformatting and FDG-PET-CT as routine imaging methods. The new minimally invasive procedures often require more exacting imaging as the surgeon does not have the same visual ?eld of view as was possible with open procedures. Thus, it is appropriate now to p- vide an update on imaging advances for the bene?t of urologists and radiologists alike. The increasing number of innovative imaging approaches to urologic tumors including CT, MRI, PET, SPECT, and endoscopic imaging can be perplexing and lead to over- and underesti- tions of the capabilities of modern imaging on the part of those who interpret them and those who use the information they provide for patient management. There is a growing “exp- tations gap” between what is expected and what is possible that needs to be closed. While previous books have focused on the more common urologic tumors such as bladder, prostate, andkidneycancer,nonehasattemptedacomprehensivereviewofthestateoftheartofimaging in most of the tumors involved in urologic oncology. Imaging in Urologic Oncology addresses these challenges. In the modern imaging department it is easy to forget how useful conventional plain rad- graphy can be in urologic diagnosis. Much of our current understanding of urologic disease is based on the “classic appearance” on intravenous urograms, cystograms, or retrograde pye- grams. Therefore, conventional imaging provides the ?rst “layer” in our understanding of u- logic tumors. The next layer is cross-sectional imaging.

Bladder -- Cancer -- Imaging. --- Kidneys -- Cancer -- Imaging. --- Prostate -- Cancer -- Imaging. --- Urogenital Neoplasms --- Diagnostic Imaging --- Male Urogenital Diseases --- Female Urogenital Diseases --- Diagnostic Techniques and Procedures --- Neoplasms by Site --- Diseases --- Neoplasms --- Diagnosis --- Female Urogenital Diseases and Pregnancy Complications --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Oncology --- Medicine --- Health & Biological Sciences --- Urology. --- Oncology. --- Medicine. --- Radiology. --- Medicine & Public Health. --- Imaging / Radiology. --- Tumors --- Genitourinary organs

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This book highlights the most efficient and latest ways to deal with cancer, focusing on IONPs. The book describes some well-designed surface modifications performed through several functional materials over the surface of IONPs, which results in the development of multifunctional IONPs-based delivery nanoplatforms by enhancing solubility, stability, and avoiding side effects on healthy cells. Several types of stimuli-responsive IONPs-based strategies are also discussed. Owing to magnetic, structural, and thermal properties, IONPs themselves can be utilized for magnetic targeting, magnetic hyperthermia, and phototherapy. Significant advancements are presented in IONPs-based immunotherapy, radiotherapy, and sonodynamic therapy for the efficient treatment of cancer. Finally, the book presents RIONs which serve as the parent platform for the development of powerful DMCAs utilized in SPECT/MRI and PET/MRI applications.

Medical physics. --- Cancer --- Nanochemistry. --- Nanotechnology. --- Biophysics. --- Medical Physics. --- Cancer Imaging. --- Nanoengineering. --- Bioanalysis and Bioimaging. --- Imaging. --- Nanoparticles. --- Treatment --- Technological innovations. --- Theranostic Nanomedicine. --- Neoplasms --- Magnetic Iron Oxide Nanoparticles. --- diagnostic imaging.

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This book presents experimental investigations and digital image processing, highlighting the interaction of polarized radiation with phase-inhomogeneous and optically anisotropic biological layers. The promising and efficient use of vector-parametric description of the formation of polarization-inhomogeneous object fields is noted. Applications of a set of Mueller-matrix polarimetry methods are highlighted. The book includes- structural and logical scheme of multi-parameter (singular, interference and layer-by-layer Stokes-polarimetric), polarization-correlation study of the structure of distributions of the number of singularities, maps of local contrast of interference distributions and layer-by-layer maps of microscopic polarization azimuth and ellipticity; determination of relationships between changes in the magnitude of statistical parameters characterizing polarization-correlation distributions and pathology of prostate tumors.

Optics. --- Image processing. --- Cancer --- Signal processing. --- Materials --- Medical physics. --- Applied Optics. --- Image Processing. --- Cancer Imaging. --- Signal, Speech and Image Processing . --- Microscopy. --- Medical Physics. --- Imaging. --- Image processing --- Digital techniques.

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This book provides an in-depth exploration of the biology of prostate cancer, from its cellular origins to its clinical manifestations and therapeutic options. In addition to thoroughly covering a variety of diagnostic methods, radical procedures, radiation therapy, hormone therapy, and surgical techniques for prostatectomy, the book seeks to improve the understanding of the development of prostate cancer. Delving into the latest research and scientific advancements, the book starts by shedding light on the critical role of genetic susceptibility, redox signaling, apoptosis, epigenomics, transcriptomics, and metabolic reprogramming in prostate cancer development and progression. In the following section key concepts in prostate cancer diagnostics are covered. This includes the diagnostic, prognostic, and theranostic potential of miRNAs in prostate cancer; the necessity of biopsy; and the importance of histopathological and molecular markers in assessing aggressivity. It also explores recent advances in tumor markers for early detection and monitoring, as well as biological markers of therapeutic response. The book concludes by offering a wealth of knowledge on current treatment options for prostate cancer, including surgical treatments, hormone therapy for advanced cases, the use of apheresis in personalized cell-mediated treatment, pharmacogenomics and precision therapy challenges and perspectives, stereotactic radiotherapy, and treatment for castration-resistant prostate cancer. Scientists and medical professionals interested in basic and clinical research in urology and oncology will find this book to be a useful reference. It is a helpful tool for preparing medical specialization in pathology, oncology, urology, clinical biochemistry, laboratory medicine, diagnostic radiology, oncologic radiology, and related fields of cancer research. With its integrative approach to diagnostics and focus on recent scientific breakthroughs, this book empowers readers to deepen their understanding of prostate cancer and enhance their ability to advance basic and clinical research to treat this pervasive disease.

Cancer. --- Cancer --- Cancer Biology. --- Cancer Therapy. --- Cancer Genetics and Genomics. --- Cancer Imaging. --- Treatment. --- Genetic aspects. --- Imaging. --- Prostate --- Diagnosis. --- Prostatic Neoplasms. --- Prostatectomy. --- Precision Medicine.