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Toxicities have been consistent undesirable companions of every form of radiation and drug cancer treatment regimens.  In addition to the potential for toxicities to devastate patients’ quality of life, they generate huge incremental financial costs, and sap patients’ ability to tolerate definitive cancer therapy.   And every new drug or biological has come with new side effects.   Historically, regimen-related toxicities were viewed as the inevitable cost of treating cancer.  But this may be about to change. Discoveries in the past dozen years have painted a new picture of the pathobiology of almost all regimen-related toxicities.  The mechanistic complexities that underlie radiation- and chemotherapy-induced tissue injury or systemic symptoms have been pieced together in an incremental sequence which now provides multiple targets for effective toxicity interventions. This book brings together, for the first time in a single volume, the most current information regarding both general principles guiding current thinking about the pathogenesis of regimen-related toxicities and the specific biological underpinnings of the most common side effects of cancer therapy.  The contents provide information that is essential to clinicians and basic and translational scientists interested in cancer therapy and its toxicities.

Antineoplastic agents -- Toxicology. --- Cancer -- Treatment -- Complications. --- Neoplasms -- Complications. --- Neoplasms. --- Cancer --- Antineoplastic agents --- Biology --- Diseases --- Kinetics --- Therapeutics --- Therapeutic Uses --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Pharmacologic Actions --- Biochemical Phenomena --- Chemical Actions and Uses --- Chemical Phenomena --- Chemicals and Drugs --- Phenomena and Processes --- Antineoplastic Agents --- Neoplasms --- Drug Therapy --- Pharmacokinetics --- Medicine --- Health & Biological Sciences --- Oncology --- Treatment --- Complications --- Toxicology --- Chemotherapy --- Complications. --- Toxicology. --- Anticancer agents --- Antineoplastic drugs --- Antineoplastics --- Antitumor agents --- Antitumor drugs --- Cytotoxic drugs --- Inhibitors, Neoplasm --- Neoplasm inhibitors --- Complications and sequelae --- Medicine. --- Cancer research. --- Pharmacology. --- Biomedicine. --- Cancer Research. --- Pharmacology/Toxicology. --- Drugs --- Oncology. --- Chemicals --- Pharmacology --- Poisoning --- Poisons --- Tumors --- Drug effects --- Medical pharmacology --- Medical sciences --- Pharmacy --- Cancer research --- Physiological effect

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Oncofertility has emerged as a way to address potential lost or impaired fertility in those with a history of cancer. Active biomedical research is developing new ways to help those afflicted with cancer to preserve their ability to have biological children. Oncofertility: Ethical, Legal, Social, and Medical Perspectives moves beyond oncofertility as a science and medical technology and begins to address the social, legal, and ethical ramifications of this emerging field. Dr. Teresa K. Woodruff establishes a team of oncologists, fertility specialists, social scientists, and education and policy makers to engage in an interdisciplinary discussion on the clinical care of women who will lose their fertility due to cancer treatment. "Cancer and its treatment will often compromise fertility. Concerns relevant to reproduction remains one of the most important issues for patients. In this text renown experts discuss the spectrum of critical issues embraced by Oncofertility." - Steven T. Rosen, M.D. Series Editor.

Cancer -- Treatment -- Complications. --- Fertility, Human -- Law and legislation. --- Fertility, Human -- Moral and ethical aspects. --- Human reproductive technology -- Social aspects. --- Infertility -- Treatment -- Social aspects. --- Infertility, Female. --- Infertility, Male. --- Technology --- Ethics --- Diseases --- Religion --- Infertility --- Humanities --- Technology, Industry, and Agriculture --- Genital Diseases, Male --- Genital Diseases, Female --- Bioethical Issues --- Neoplasms --- Infertility, Female --- Biomedical Technology --- Infertility, Male --- Religion and Medicine --- Female Urogenital Diseases --- Male Urogenital Diseases --- Technology, Industry, Agriculture --- Female Urogenital Diseases and Pregnancy Complications --- Medicine --- Health & Biological Sciences --- Oncology --- Cancer --- Cells --- Fertility, Human. --- Treatment --- Complications. --- Cryopreservation. --- Human fertility --- Natality --- Complications and sequelae --- Medicine. --- Ethics. --- Public health. --- Oncology. --- Medical research. --- Quality of life. --- Medicine & Public Health. --- Public Health. --- Quality of Life Research. --- Demography --- Human reproduction --- Cryopreservation of organs, tissues, etc. --- Preservation --- Oncology  . --- Quality of Life --- Research. --- Life, Quality of --- Economic history --- Human ecology --- Life --- Social history --- Basic needs --- Human comfort --- Social accounting --- Work-life balance --- Deontology --- Ethics, Primitive --- Ethology --- Moral philosophy --- Morality --- Morals --- Philosophy, Moral --- Science, Moral --- Philosophy --- Values --- Tumors --- Community health --- Health services --- Hygiene, Public --- Hygiene, Social --- Public health services --- Public hygiene --- Social hygiene --- Health --- Human services --- Biosecurity --- Health literacy --- Medicine, Preventive --- National health services --- Sanitation