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Symposium on molecular action of mutagenic and carcinogenic agents
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Year: 1964 Publisher: Philadelphia (Pa.): Wistar institute press,

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Carcinogen
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ISBN: 9535170104 9535106589 Year: 2012 Publisher: IntechOpen

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During the last decades, cancer diseases have increased all over the world. The low quality of food and strong pollution of environment are the main prerequisites for carcinogenesis. The main problem for scientists is to find strategy for prevention of cancer diseases. Therefore, the information about the models for studying carcinogenesis and mutagens which appear during cooking, environmental pollutants, and tests for specific detection of carcinogens is particularly important. The book "Carcinogen" is intended for biologists, researchers, students in medical sciences and professionals interested in associated areas.


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Sittig's handbook of toxic and hazardous chemicals and carcinogens
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ISBN: 1283293781 9786613293787 1437778704 1437778690 1455730157 9781437778700 9781455730155 9781437778694 Year: 2008 Publisher: Norwich, NY : William Andrew,

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For more than a quarter century, Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens has proven to be among the most reliable, easy-to-use and essential reference works on hazardous materials. Sittig's 5th Edition remains the lone comprehensive work providing a vast array of critical information on the 2,100 most heavily used, transported, and regulated chemical substances of both occupational and environmental concern. Information is the most vital resource anyone can have when dealing with potential hazardous substance accidents or acts of terror. Sittig's provides ex


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Cancer causing substances
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ISBN: 1789231418 178923140X 1838812954 Year: 2018 Publisher: IntechOpen

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Cancer risk factors include exposure to certain substances, which may contribute to the development of cancer. However, substances can have different levels of cancer-causing potential, and the risk of developing cancer is dependent on several factors, including individual genetic background and the amount and duration of the exposure. This book focuses on various cancer risk factors, covering numerous known, probable, and possible carcinogens; their role in carcinogenesis; mechanisms of carcinogenicity; and methods for detecting carcinogens. And due to the growing concerns over the effects that substances and environmental exposures can have on human health, the chapters also emphasize on the vital need for further topic-related research as well as development and implementation of beneficial approaches.


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Fundamental and guiding principles for (Q)SAR analysis of chemical carcinogens with mechanistic considerations
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ISBN: 9264274790 Year: 2017 Publisher: Paris : OECD Publishing,

Chemical carcinogens : some guidelines for handling and disposal in the laboratory.
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ISBN: 0387167196 3540167196 3642713424 9783540167198 9780387167190 Year: 1986 Publisher: Berlin Springer

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Book
Essai n° 451 : Études de cancérogénèse
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ISBN: 9789264071193 Year: 2018 Publisher: Paris : OECD Publishing,

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L’objectif d’une étude à long terme de cancérogénèse est d’observer des animaux d’essai au cours de la majeure partie de leur durée de vie, pour suivre le développement éventuel de lésions néoplasiques durant ou après l’exposition à de diverses doses d’une substance d’essai par une voie d’administration appropriée. Cette Ligne directrice concerne principalement des essais sur rats et souris, et une administration orale. Les deux sexes sont employés. Chaque groupe de dose et groupe témoin contient au moins 50 animaux de chaque sexe. Trois niveaux de dose et un témoin sont employés au moins. La substance d’essai est administrée chaque jour par voix orale (dermale ou par inhalation), et le mode d’exposition est ajusté selon le profil toxicocinétique de la substance d’essai. La durée de l’étude est normalement de 24 mois pour les rongeurs. Pour des souches de souris spécifiques, une durée de 18 mois peut être plus appropriée. La clôture de l’essai est envisagée lorsque le nombre de survivants dans les groupes de dose la plus faible ou dans le groupe témoin tombe en dessous de 25%. Les résultats de ces études incluent des mesures (pesée, consommation de nourriture), et au moins, des observations quotidiennes détaillées, ainsi que l’autopsie générale et l’histopathologie.


Book
Carcinogenic risks strategies for intervention
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ISBN: 9283211251 Year: 1979 Publisher: Lyon International agency for research on cancer

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CRC handbook of identified carcinogens and noncarcinogens : carcinogenicity-mutagenicity database
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ISBN: 0849332001 Year: 1985 Publisher: Boca Raton CRC Press

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Ingested nitrate and nitrite, and cyanobacterial peptide toxins : this publication represents the views and expert opinions of an IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, which met in Lyon, 14-21 June 2006
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ISSN: 10171606 ISBN: 9789283212942 Year: 2010 Volume: 94 Publisher: Lyon IARC Press

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