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This book addresses the unique features of four microorganisms that constitute the top bioterror threat agents: Bacillus anthracis; Yersinia pestis, Francisella tularensis and Orthopoxviruses. Side-by-side updated information about their pathogenisis, virulence and epidemiology is provided in a single volume, allowing for evaluation of common features as well as common strategies for defense. Classical microbiological as well as genomic, proteomic & transcriptomic approaches towards development of strategies of novel prophylactic and post-exposure treatment and related aspects of diagnostics and bioforensics are covered. Written by top scientists, this book will be of major interest to all researchers interested in the intricate biology of highly pathogenic microorganisms, to scientists and clinicians interested in microbial pathogenesis and prevention, and to a wide range of professionals dealing with the various aspects of bio-defense.

Biological weapons. --- Communicable diseases. --- Medical microbiology. --- Pathogenic microorganisms. --- Pathogenic microorganisms --- Chordopoxvirinae --- DNA Virus Infections --- Bacterial Infections and Mycoses --- Organisms --- Orthopoxvirus --- Bacterial Infections --- Bacteria --- Poxviridae Infections --- Virus Diseases --- Diseases --- Poxviridae --- DNA Viruses --- Vertebrate Viruses --- Viruses --- Biology --- Microbiology & Immunology --- Health & Biological Sciences --- Disease-causing microorganisms --- Micro-organisms, Pathogenic --- Pathogens --- Medicine. --- Vaccines. --- Microbiology. --- Bacteriology. --- Microbial genetics. --- Microbial genomics. --- Biomedicine. --- Medical Microbiology. --- Vaccine. --- Eukaryotic Microbiology. --- Microbial Genetics and Genomics. --- Microorganisms --- Medical microbiology --- Virulence (Microbiology) --- Genomics --- Microbial genetics --- Genetics --- Microbiology --- Biologicals --- Microbial biology

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Though smallpox was eradicated from the planet two decades ago, recent terrorist acts have raised the horrific possibility that rogue states, laboratories, or terrorist groups are in possession of secret stockpiles of the virus that causes the disease, and may be preparing to unleash it on target populations.

Cultures and culture media. --- Epidemiology. --- Health Policy. --- International cooperation. --- Prevention. --- prevention & control. --- Smallpox. --- Variola virus. --- Smallpox --- Orthopoxvirus --- Public Policy --- North America --- Internationality --- Europe, Eastern --- Poxviridae Infections --- Social Sciences --- DNA Virus Infections --- Social Control Policies --- Americas --- Chordopoxvirinae --- Europe --- Social Control, Formal --- Policy --- Poxviridae --- Virus Diseases --- Geographic Locations --- Anthropology, Education, Sociology and Social Phenomena --- Sociology --- DNA Viruses --- Health Care Economics and Organizations --- Diseases --- Geographicals --- Health Care --- Viruses --- Vertebrate Viruses --- Organisms --- International Cooperation --- Health Policy --- Variola virus --- Russia --- United States --- Public Health --- Health & Biological Sciences --- Communicable Diseases --- Healthcare Policy --- National Health Policy --- Health Policies --- Health Policy, National --- Healthcare Policies --- National Health Policies --- Policy, Health --- Policy, Healthcare --- Policy, National Health --- Policy Making --- Alastrim --- Variola --- Variola Minor --- Minor, Variola --- Minors, Variola --- Variola Minors --- Variolas --- Poxvirus variolae --- Smallpox Virus --- Smallpox Viruses --- Variola viruses --- Treaties --- Foreign Aid --- Aid, Foreign --- Cooperation, International --- Treaty --- Animal Viruses --- Zoophaginae --- Animal Virus --- Virus --- Virus, Animal --- Viruses, Animal --- Genetic Vectors --- Microbiology --- Community-Based Distribution --- Contraceptive Distribution --- Delivery of Healthcare --- Dental Care Delivery --- Distribution, Non-Clinical --- Distribution, Nonclinical --- Distributional Activities --- Healthcare --- Healthcare Delivery --- Healthcare Systems --- Non-Clinical Distribution --- Nonclinical Distribution --- Delivery of Dental Care --- Health Care Delivery --- Health Care Systems --- Activities, Distributional --- Activity, Distributional --- Care, Health --- Community Based Distribution --- Community-Based Distributions --- Contraceptive Distributions --- Deliveries, Healthcare --- Delivery, Dental Care --- Delivery, Health Care --- Delivery, Healthcare --- Distribution, Community-Based --- Distribution, Contraceptive --- Distribution, Non Clinical --- Distributional Activity --- Distributions, Community-Based --- Distributions, Contraceptive --- Distributions, Non-Clinical --- Distributions, Nonclinical --- Health Care System --- Healthcare Deliveries --- Healthcare System --- Non Clinical Distribution --- Non-Clinical Distributions --- Nonclinical Distributions --- System, Health Care --- System, Healthcare --- Systems, Health Care --- Systems, Healthcare --- Healthcare Economics and Organizations --- Health Care Economics --- Health Economics --- Healthcare Economics --- Care Economic, Health --- Economic, Health --- Economic, Health Care --- Economic, Healthcare --- Economics, Health Care --- Health Care Economic --- Health Economic --- Healthcare Economic --- DNA Virus --- Virus, DNA --- Viruses, DNA --- General Social Development and Population --- Viral Diseases --- Viral Infections --- Virus Infections --- Disease, Viral --- Disease, Virus --- Diseases, Viral --- Diseases, Virus --- Infection, Viral --- Infection, Virus --- Infections, Viral --- Infections, Virus --- Viral Disease --- Viral Infection --- Virus Disease --- Virus Infection --- Poxviruses --- Policies --- Regulation --- Social Control --- Control, Social --- Controls, Social --- Formal Social Control --- Formal Social Controls --- Regulations --- Social Controls --- Control Policies, Social --- Control Policy, Social --- Policies, Social Control --- Policy, Social Control --- Social Control Policy --- Infections, DNA Virus --- DNA Virus Infection --- Infection, DNA Virus --- Virus Infection, DNA --- Virus Infections, DNA --- Science, Social --- Sciences, Social --- Social Science --- Globalization --- International Aspects --- International Perspectives --- International Relations --- Multinational Aspects --- Multinational Perspectives --- Aspect, International --- Aspect, Multinational --- Aspects, International --- Aspects, Multinational --- International Aspect --- International Perspective --- Multinational Aspect --- Multinational Perspective --- Perspective, International --- Perspective, Multinational --- Perspectives, International --- Perspectives, Multinational --- Relations, International --- International Law --- Infections, Poxviridae --- Infections, Poxvirus --- Milker's Nodes --- Poxvirus Infections --- Infection, Poxviridae --- Infection, Poxvirus --- Milker Nodes --- Milker's Node --- Milkers Nodes --- Node, Milker's --- Nodes, Milker's --- Poxviridae Infection --- Poxvirus Infection --- Affirmative Action --- Migration Policy --- Population Policy --- Social Protection --- Social Policy --- Action, Affirmative --- Migration Policies --- Policies, Migration --- Policies, Population --- Policies, Public --- Policies, Social --- Policy, Migration --- Policy, Population --- Policy, Public --- Policy, Social --- Population Policies --- Protection, Social --- Public Policies --- Social Policies --- Camelpox virus --- Horsepox virus --- Raccoonpox virus --- Skunkpox virus --- Taterapox virus --- Volepox virus --- Camelpox viruses --- Horsepox viruses --- Orthopoxviruses --- Raccoonpox viruses --- Skunkpox viruses --- Taterapox viruses --- Volepox viruses --- virus, Camelpox --- virus, Horsepox --- virus, Raccoonpox --- virus, Skunkpox --- virus, Taterapox --- virus, Volepox --- Small pox --- Varioloid --- Poxvirus diseases --- Prevention --- Epidemiology --- Cultures and culture media --- Vertebrates --- virology --- Russian Federation (Europe) --- Russian SFSR --- Russian S.F.S.R. --- Geographic Location --- Northern Europe --- Southern Europe --- Western Europe --- America --- Eastern Europe --- Northern America --- Health Care Policies --- Care Policies, Health --- Health Care Policy --- Policies, Health --- Policies, Health Care --- Policies, Healthcare --- Policy, Health Care