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Comprehensive biochemistry.
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ISBN: 1483222136 1483197107 1322340641 9781483197104 Year: 1965 Publisher: Amsterdam ; London : Elsevier Publishing Company,

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Hydrolytic Reactions

Vitamins and coenzymes.
Authors: ---
ISBN: 0121818802 0121818799 0121818829 0121819620 0121819663 0121819671 012182022X 0121820238 0121821803 0121821811 012182182X 0121821838 9780121818821 9780121819620 9780121819675 9780121819668 9780121820237 9780121820220 9780121818791 9780121821814 9780121821807 Year: 1971 Volume: 18 Publisher: New York (N.Y.) Academic press

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Abstract

The critically acclaimed laboratory standard, Methods in Enzymology, is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. The series contains much material still relevant today - truly an essential publication for researchers in all fields of life sciences.


Book
Stearoyl-CoA Desaturase Genes in Lipid Metabolism
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ISBN: 1461479681 1493901532 146147969X Year: 2013 Publisher: New York, NY : Springer New York : Imprint: Springer,

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James Ntambi has gathered top authors to write about the remarkable growth of research on the role of the stearoyl-CoA desaturase (SCD) genes in metabolism in different species including human. The book shows that beginning with simple cellular models of differentiation a broad and comprehensive analysis of the SCD gene family in a number of species and biological systems has been carried out over the course of the last twenty five years. SCD is a central enzyme in lipid metabolism that synthesizes monounsaturated fatty acids (MUFA) from saturated fatty acid precursors. At first glance, SCD would be considered a housekeeping enzyme because its product oleate is a well-known MUFA that is abundant in many dietary sources and tissue lipids. A particular highlight in the chapters of the book is that MUFAs may have signaling properties that regulate metabolism. For example, a proper ratio of saturated to MUFA contributes to membrane fluidity, and oleate has also been implicated as a mediator of signal transduction, cellular differentiation and metabolic homeostasis. It is also highlighted that SCD-1 repression mediates the metabolic effects of the hormone leptin. Conditional alleles and corresponding tissue-specific knockout mouse models for many of the SCD gene isorfms have provided a wealth of information on not only tissue-specific fatty acid metabolism but also the key transcription factors that regulate SCD expression under a variety of metabolic and genetic backgrounds. The studies described indicate that control of SCD expression occurs via a series of complex signal transduction schemes making SCD one of the most highly studied lipogenic gene families to date.


Book
Metal-carbon bonds in enzymes and cofactors
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ISBN: 3110436582 9783110436587 3110442795 9783110442793 Year: 2009 Publisher: Cambridge, UK : RSC Publishing,

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The occurrence of a wide variety of metal-carbon bonds in living organisms, ranging from bacteria to humans, is only recently recognized. Of course, the historical examples are the B12 coenzymes containing cobalt-carbon bonds, but now such bonds are also known for nickel, iron, copper, and other transition metal ions. There is no other comparable book; MILS-6, written by 17 experts, summarizes the most recent insights into this fascinating topic.

Methods in Enzymology : Quinones and Quinone Enzymes, Part A.
Authors: ---
ISSN: 00766879 ISBN: 0121827828 0121827860 9786611011499 1281011495 0080497209 9786611011451 1281011452 0080497160 9780121827861 9780121827823 Year: 2004 Volume: 378-382 Publisher: Burlington : Elsevier Science,

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Quinones are members of a class of aromatic compounds with two oxygen atoms bonded to the ring as carbonyl groups. This volume covers the role of quinines enzymes in cellular signalling and modulation of gene expression.*Coenzyme Q: Detection and Quinone Reductases*Plasma Membrane Quinone Reductases*Quinones, Cellular Signaling, and Modulation of Gene Expression

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