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Trauma is still a leading cause of death in patients below 40 years of age. Clinical management of severely injured patients is challenging in all phases of treatment during the clinical course. Numerous factors, such as injury severity, injury pattern, patient characteristics and trauma system, affect the decision-making process in our patients. After the successful initial management of an unstable multiply injured patient, secondary definitive surgeries and reconstructions may have a risk for further systemic complications and the deterioration of the patient’s physiology. A “Safe Definitive Surgery” (SDS) concept considers the dynamics of the clinical course (prehospital, operations, complications, etc.) and the patient’s physiology. Due to the repeated re-evaluation and assessment of the patient’s clinical course, dynamics and adaptation of the treatment strategy, the safe management of polytraumatized patients is possible. Many unanswered questions still exist and need to be addressed in future studies: Which patients profit by the damage control strategy and which do not? When is it best to start with the definitive fixation of fractures in multiply injured patients? How can one improve the quality of life in polytraumatized patients? What are the strategies in elderly severely injured patients? With this Special Issue, we would like to stimulate research in the field of polytrauma in order to shed light on the above-mentioned questions

Medicine --- pelvic ring fracture --- PCCD --- position --- associated injuries --- geriatric trauma --- scoring --- polytrauma --- ISS --- AIS --- geriatric patients --- orthogeriatric --- E-bike injuries --- outcome --- injury pattern comparison --- traumatic injury --- reactive oxygen species --- phagocytosis --- CD14 --- CD16 --- CD62L --- fMLP --- PMA --- emergency surgery --- trauma team competence --- trauma system --- life-saving intervention --- trauma --- non-invasive external pelvic stabilizers --- bleeding --- pelvic fractures --- post mortem analysis --- biomechanical force --- pneumatic pelvic sling VBM® --- T-POD® --- cloth sling --- SAM Sling® --- trauma victims --- prehospital death --- Injury Severity Score (ISS) --- hemorrhage --- shock --- resuscitation --- coagulopathy --- oxygen transport --- endotheliopathy --- microcirculation --- macrocirculation --- orthopaedic trauma --- nutritional deficiencies --- vitamins --- lower extremity --- wound complications --- nutrition wound healing --- platelets --- immune system --- posttraumatic organ failure --- posttraumatic lung dysfunction --- posttraumatic hyperinflammation --- I-FABP --- biomarker --- intestinal damage --- hemorrhagic shock --- major trauma

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Malnutrition lurks in the background of hospitalized medical patients. A large proportion of patients are malnourished upon hospital admission and patients often experience further nutritional deterioration during their stay and during disease recovery. However, although the negative effects of malnutrition on the outcomes of patients are well recognized, we still struggle to identify appropriate patients and efficacious nutritional interventions to overcome this problem. Recent studies have produced convincing evidence that adequate and timely nutritional management of medical in-patients can contribute to the prevention of negative consequences and thus improve the clinical outcome of patients. This Special Issue of the Journal of Clinical Medicine focuses on multiple practical aspects of nutritional management of medical in-patients, from screening for nutritional risk to the practical implementation of nutritional therapy and its possible complications, including financial aspects, to increasing clinician awareness and knowledge of nutritional care in hospitals.

Research & information: general --- Biology, life sciences --- Food & society --- type 1 diabetes mellitus --- bioelectrical impedance analysis --- phase angle --- children --- adolescents --- protein --- malnutrition --- critical care --- mortality --- outcomes --- hospital readmission --- ICU Survivors --- inflammation --- nutritional assessment --- biomarkers --- albumin --- prealbumin --- IGF-1 --- elderly --- prognostic marker --- Pediatric Intensive Care Unit --- enteral nutrition --- early parenteral nutrition --- critical illness --- iron --- copper --- selenium --- zinc --- thiamine --- vitamin B12 --- obesity --- glucose control --- hyperglycemia --- parenteral nutrition --- nutritional support --- insulin --- Geriatric patients --- older persons --- therapy --- interventions --- chronic critical illness --- Nutrition Risk Screening (NRS-2002) --- age --- nutrition --- vasopressors --- shock --- glucose --- diabetes --- underfeeding --- economic challenges --- nutritional management --- mid-arm muscle circumference --- dual-energy X-ray absorptiometry --- computed tomography --- fat-free mass --- appendicular skeletal muscle mass --- lean soft tissue --- skeletal muscle index --- chronic disease --- old --- anorexia nervosa --- refeeding syndrome --- weight gain --- length of stay --- nutritional risk screening --- monitoring --- micronutrient deficiency --- oral nutritional supplements --- artificial nutrition --- gastroparesis --- dumping syndrome --- pathophysiology --- clinical presentation --- treatment --- nutritional therapy --- cancer --- cachexia --- sarcopenia --- survival --- nutritional support team --- efficacy --- metabolic syndrome --- insulin resistance --- dietary pattern --- carbohydrates --- fat --- indirect calorimetry --- indirect calorimeter --- resting energy expenditure --- nutrition therapy --- medical nutrition therapy --- intensive care unit --- intermediate care unit --- critically ill patients --- nutritional counselling --- nursing --- e-counselling --- dehydration --- dysphagia --- fluid intake --- water --- cirrhosis --- ascites --- sarcopenic obesity --- vitamins --- micronutrients --- all-in-one parenteral admixture --- compatibility --- stability --- pharmaceutical expertise --- drug admixing --- drug administration --- hospital --- nutrition care --- continuity of care --- process indicators --- benchmarking --- disease related malnutrition. --- diagnosis --- management --- hypophosphatemia --- n/a

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• Reference Manager
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Malnutrition lurks in the background of hospitalized medical patients. A large proportion of patients are malnourished upon hospital admission and patients often experience further nutritional deterioration during their stay and during disease recovery. However, although the negative effects of malnutrition on the outcomes of patients are well recognized, we still struggle to identify appropriate patients and efficacious nutritional interventions to overcome this problem. Recent studies have produced convincing evidence that adequate and timely nutritional management of medical in-patients can contribute to the prevention of negative consequences and thus improve the clinical outcome of patients. This Special Issue of the Journal of Clinical Medicine focuses on multiple practical aspects of nutritional management of medical in-patients, from screening for nutritional risk to the practical implementation of nutritional therapy and its possible complications, including financial aspects, to increasing clinician awareness and knowledge of nutritional care in hospitals.

type 1 diabetes mellitus --- bioelectrical impedance analysis --- phase angle --- children --- adolescents --- protein --- malnutrition --- critical care --- mortality --- outcomes --- hospital readmission --- ICU Survivors --- inflammation --- nutritional assessment --- biomarkers --- albumin --- prealbumin --- IGF-1 --- elderly --- prognostic marker --- Pediatric Intensive Care Unit --- enteral nutrition --- early parenteral nutrition --- critical illness --- iron --- copper --- selenium --- zinc --- thiamine --- vitamin B12 --- obesity --- glucose control --- hyperglycemia --- parenteral nutrition --- nutritional support --- insulin --- Geriatric patients --- older persons --- therapy --- interventions --- chronic critical illness --- Nutrition Risk Screening (NRS-2002) --- age --- nutrition --- vasopressors --- shock --- glucose --- diabetes --- underfeeding --- economic challenges --- nutritional management --- mid-arm muscle circumference --- dual-energy X-ray absorptiometry --- computed tomography --- fat-free mass --- appendicular skeletal muscle mass --- lean soft tissue --- skeletal muscle index --- chronic disease --- old --- anorexia nervosa --- refeeding syndrome --- weight gain --- length of stay --- nutritional risk screening --- monitoring --- micronutrient deficiency --- oral nutritional supplements --- artificial nutrition --- gastroparesis --- dumping syndrome --- pathophysiology --- clinical presentation --- treatment --- nutritional therapy --- cancer --- cachexia --- sarcopenia --- survival --- nutritional support team --- efficacy --- metabolic syndrome --- insulin resistance --- dietary pattern --- carbohydrates --- fat --- indirect calorimetry --- indirect calorimeter --- resting energy expenditure --- nutrition therapy --- medical nutrition therapy --- intensive care unit --- intermediate care unit --- critically ill patients --- nutritional counselling --- nursing --- e-counselling --- dehydration --- dysphagia --- fluid intake --- water --- cirrhosis --- ascites --- sarcopenic obesity --- vitamins --- micronutrients --- all-in-one parenteral admixture --- compatibility --- stability --- pharmaceutical expertise --- drug admixing --- drug administration --- hospital --- nutrition care --- continuity of care --- process indicators --- benchmarking --- disease related malnutrition. --- diagnosis --- management --- hypophosphatemia --- n/a