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Book
Detection and Typing Strategies for Pathogenic Escherichia coli
Authors: --- --- ---
ISBN: 9781493923465 1493923455 9781493923458 1493923463 Year: 2015 Publisher: New York, NY : Springer New York : Imprint: Springer,

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This Brief will review the methods that are currently available for the detection, isolation, and typing of pathogenic E. coli with a particular focus on foodborne diseases caused by the Shiga toxigenic E. coli group, which have been implicated in a number of significant outbreaks in recent years. Pathogenic forms of E. coli can cause a variety of diarrheal diseases in hosts due to the presence of specific colonization and virulence factors, and pathogenicity-associated genes, which are generally not present in other E. coli. Six pathotypes of pathogenic E. coli are recognized (Shiga toxigenic E. coli, Enteropathogenic E. coli, Enterotoxigenic E. coli, Enteroinvasive E. coli, Enteroaggregative E. coli and Diffusely Adherent E. coli) and certain strains among these groups are major public health concerns due to the severity of disease that they can cause. Methods to detect and isolate these pathogens from a variety of sources are constantly evolving. In addition, the accumulation of knowledge on these pathogens allows for improved intervention strategies.

E. coli in motion
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ISBN: 0387008888 9786610189014 1280189010 0387216383 Year: 2004 Publisher: New York : Springer,

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The bacterium Escherichia coli – E. coli for short – has long been the organism of choice for unraveling biochemical pathways, deciphering the genetic code, learning how DNA is replicated and read, and even for manufacturing proteins of commercial interest. For some thirty years, it also has been a model for studying the molecular biology of behavior. E. coli swims in a purposeful manner, propelled by long thin helical filaments, each driven at its base by a reversible rotary engine. As a microscopic organism immersed in an aqueous environment, it has mastered physical constraints utterly different from any that we know, devising sensors, comparators, and motors on the nanometer scale. This cross-disciplinary monograph describes these feats in a manner accessible to scientists, engineers, and others not trained in microbiology who would like to learn more about living machines. It treats the history of the subject, the physiology, physics, biochemistry and genetics, largely from first principles. It is all about a small but remarkably sophisticated friend who lives in your gut. Topics discussed include: How does E. coli move about? How do cells decide whether life is getting better or worse? What is the machinery that makes this behavior possible? How is the construction of this machinery programmed? How does this machinery work? What remains to be discovered?


Book
Advances in Yersinia Research
Authors: --- ---
ISBN: 1461435609 9786613798640 1461435617 1282056697 Year: 2012 Publisher: New York, NY : Springer New York : Imprint: Springer,

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This book presents cutting edge advances on Yersinia discussed on the 10th International Symposium on Yersinia held in Recife, Brazil 23-27 October 2010. The 42 chapters written by top scientists from around the world features reviews and research articles distributed into 8 topic areas: Evolution; Epidemiology; Detection, Diagnosis and Identification; Immune Response; Pathogenesis and Transmission; Metabolic and Pathogenicity Factors; Regulation; and Approaches to New Therapies. A must read for researchers in the field.


Book
Systems Biology and Biotechnology of Escherichia coli
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ISBN: 9048181186 1402093934 9786612047855 128204785X 1402093942 Year: 2009 Publisher: Dordrecht : Springer Netherlands : Imprint: Springer,

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Systems biology is changing the way biological systems are studied by allowing us to examine the cell and organism as a whole. Systems biotechnology allows optimal design and development of upstream to downstream bioprocesses by taking a systems-approach. E. Coli has been a model organism for almost all biological and biotechnological studies. This book brings together for the first time the state-of-the-art reviews by the world-leading experts on systems biology and biotechnological applications of E. coli. The topics covered include genomics and functional genomics, resources for systems biology, network analysis, genome-scale metabolic reconstruction, modelling and simulation, dynamic modelling and simulation, systems-level analysis of evolution, plasmids and expression systems, protein synthesis, production and export, engineering the central metabolism, synthetic biology, and systems metabolic engineering of E. coli. This book provides readers with guidance on how a complex biological system can be studied using E. Coli as a model organism. It also presents how to perform synthetic biology and systems metabolic engineering studies on E. Coli with successful examples, the approaches of which can be extended to other organisms. This book will be a complete resource for anyone interested in systems biology and biotechnology.


Book
Pasteurella multocida : Molecular Biology, Toxins and Infection
Authors: --- ---
ISBN: 3642438563 3642310168 9786613943255 3642310176 128363080X Year: 2012 Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer,

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It is more than 125 years since Louis Pasteur identified as the causative agent of “choléra des poules” the bacterium that now bears his name. Since that time, Pasteurella multocida has been recognized as the causative agent of a wide range of infections in a wide range of animal species as well as in humans.  Indeed, the species name multocida could be literally translated as “multi-killer”. The term pasteurellosis is now widely applied to describe infections of mammals and birds caused by P. multocida.  It is therefore surprising that a detailed knowledge of the cellular and molecular basis for pathogenesis in pasteurellosis lags behind what has been elucidated for many other bacterial species.  In particular, the molecular basis for host predilection remains completely unknown.    This volume brings together contributions from experts in the field of Pasteurella research.  It covers areas such as comparative genomics, pathogenic mechanisms, bacterial proteomics, as well as a detailed description and analysis of Pasteurella multocida toxin and its interaction with host tissues, cells, immune system, and signalling pathways. .


Book
Rheumatoid Arthritis and Proteus
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ISBN: 0857299492 0857299506 Year: 2012 Publisher: London : Springer London : Imprint: Springer,

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Rheumatoid Arthritis and Proteus explores the idea that Rheumatoid arthritis is caused by a urinary tract infection as a result of Proteus bacteria. Rheumatoid arthritis is a severe, painful and crippling disease affecting millions of people throughout the world, especially women. Genetic studies over the last 30 years have shown that individuals who possess the white cell blood groups HLA-DR1/4 carry a susceptibility sequence and are more likely to develop the disease.   This book uses the methods of Sir Karl Popper, the philosopher of science, to present 12 “Popper sequences” which have been identified to indicate that Proteus is the causative agent of Rheumatoid Arthritis. Rheumatoid Arthritis and Proteus proposes that Anti-Proteus therapies should be followed as early as possible to prevent the crippling and irreversible joint deformities that occur in Rheumatoid Arthritis.


Book
Ankylosing spondylitis and Klebsiella
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ISBN: 1447142993 1447143000 1283848740 Year: 2013 Publisher: London : Springer London : Imprint: Springer,

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Ankylosing spondylitis and Klebsiella is a comprehensive and informative text on the cause of Ankylosing spondylitis. Ankylosing spondylitis (AS) is a condition which affects 20 million people worldwide and is likely caused or initiated by a bowel infection from Klebsiella bacteria.   When a patient is infected by Klebsiella bacteria, his or her immune system will make antibodies against all the antigens or molecules found in the microbe. Because some of the bacterial antigens resemble self tissues, the anti-bacterial antibodies will attack not only the bacteria but also the self tissues such as the joints and the cells having the same HLA molecules, which is how the disease AS starts.  This is the concept of molecular similarity or “molecular mimicry” which previously has been found to work in two other autoimmune diseases; rheumatic fever and rheumatoid arthritis.   The first paper on this subject was published in 1976 and since then over 100 papers on rheumatological topics have been published, from Prof Ebringer’s group, at the Division of Life Sciences, King’s College in London, UK.   The relevant information from these papers is extracted and presented in this book format making it accessible to health professionals, research institutions, pharmaceutical companies and universities and the general public.  .

Genes and proteins underlying microbial urinary tract virulence : basic aspects and applications
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ISBN: 0306464551 1280043040 9786610043040 0306468409 Year: 2002 Volume: 485 Publisher: New York, New York : Kluwer Academic Publishers,

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Proceedings of the FEMS Symposium on Genes and Proteins Underlying Microbial Urinary Tract Virulence: Basic Aspects and Applications, held September 16-19, 1999, in Pécs, Hungary. Urinary tract infections are among the most frequent diseases caused by microbial pathogens. In this volume, researchers, clinical microbiologists and clinicians exchange the latest ideas covering four major aspects of this important topic: Genetic information, synthesis and assembly of virulence factors in urinary pathogens; Regulation of genes involved in the phenotypic appearance of virulence; Host-parasite interactions determining the process and outcome of the infection; Possible applications of the above aspects in diagnosis, therapy and prevention.

Escherichia coli O157:H7 in ground beef : review of a draft risk assessment
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ISBN: 0309086272 9786610182992 1280182997 0309503922 9780309503921 9780309086271 0309168945 Year: 2002 Publisher: Washington, D.C. : National Academies Press,

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Keywords

MEDICAL --- Public Health --- Escherichia coli infections --- Escherichia coli O157:H7 --- Beef --- Public health --- Risk Assessment --- Cattle --- Escherichia coli O157 --- Food Microbiology --- Meat --- Escherichia coli Infections --- Environmental Microbiology --- Medicine --- Enterohemorrhagic Escherichia coli --- Environment and Public Health --- Risk Management --- Food --- Risk --- Food Contamination --- Food Technology --- Ruminants --- Health --- Epidemiologic Measurements --- Enterobacteriaceae Infections --- Shiga-Toxigenic Escherichia coli --- Artiodactyla --- Environmental Pollution --- Food Industry --- Probability --- Gram-Negative Bacterial Infections --- Food and Beverages --- Organization and Administration --- Health Care --- Microbiology --- Population Characteristics --- Food Safety --- Health Occupations --- Health Services Administration --- Mammals --- Statistics as Topic --- Technology, Industry, Agriculture --- Disciplines and Occupations --- Industry --- Escherichia coli --- Biology --- Bacterial Infections --- Biological Science Disciplines --- Escherichia --- Epidemiologic Methods --- Bacterial Infections and Mycoses --- Technology, Industry, and Agriculture --- Health Care Evaluation Mechanisms --- Vertebrates --- Quality of Health Care --- Enterobacteriaceae --- Diseases --- Natural Science Disciplines --- Chordata --- Investigative Techniques --- Gram-Negative Facultatively Anaerobic Rods --- Gammaproteobacteria --- Health Care Quality, Access, and Evaluation --- Animals --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Gram-Negative Bacteria --- Proteobacteria --- Eukaryota --- Organisms --- Bacteria --- Microbiology & Immunology --- Health & Biological Sciences --- Risk factors --- Transmission --- Escherichia coli O157:H7. --- Beef. --- Public health. --- Risk factors. --- Transmission. --- Community health --- Health services --- Hygiene, Public --- Hygiene, Social --- Public health services --- Public hygiene --- Sanitary affairs --- Social hygiene --- EHEC (Bacterium) --- Colibacillosis --- Human services --- Biosecurity --- Health literacy --- Medicine, Preventive --- National health services --- Sanitation --- Gram-negative bacterial infections

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