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Calcium --- Cellular control mechanisms --- Intracellular calcium --- Metabolism --- Disorders --- Metabolism

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Plants use the Sun's energy to synthesize the basic biomolecules that make up all the organic matter of all organisms of terrestrial ecosystems, including ourselves. Therefore, understanding their adaptive mechanisms to variations of environmental factors, both biotic and abiotic, is fundamental, and particularly relevant in the current context of rapid climate change. Some of the most important adaptive mechanisms of plants are the electrical and chemical signaling systems for the exchange of information between proximally and distally located cells. These signalling systems allow plants to dynamically coordinate the activities of all cells under a diversity of situations. In this Research Topic, we present eight articles that bring up new hypothesis and data to understand the mechanisms of systemic electrical signaling and the central role that it plays in adapting the whole plant to different stresses, as well as new findings on intracellular calcium and nitric oxide-based signaling pathways under stress, which could be extrapolated to non-plant research.

nitric oxide --- environmental stress --- photosynthesis --- Arabidopsis --- phloem --- intracellular calcium --- circumnutation --- action potential --- plant electrophysiology --- ion channels

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Plants use the Sun's energy to synthesize the basic biomolecules that make up all the organic matter of all organisms of terrestrial ecosystems, including ourselves. Therefore, understanding their adaptive mechanisms to variations of environmental factors, both biotic and abiotic, is fundamental, and particularly relevant in the current context of rapid climate change. Some of the most important adaptive mechanisms of plants are the electrical and chemical signaling systems for the exchange of information between proximally and distally located cells. These signalling systems allow plants to dynamically coordinate the activities of all cells under a diversity of situations. In this Research Topic, we present eight articles that bring up new hypothesis and data to understand the mechanisms of systemic electrical signaling and the central role that it plays in adapting the whole plant to different stresses, as well as new findings on intracellular calcium and nitric oxide-based signaling pathways under stress, which could be extrapolated to non-plant research.

nitric oxide --- environmental stress --- photosynthesis --- Arabidopsis --- phloem --- intracellular calcium --- circumnutation --- action potential --- plant electrophysiology --- ion channels

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Apoptosis: Involvement of Oxidative Stress and Intracellular Ca2+ Homeostasis, presents a concise synthesis of the current knowledge and recent advances in the mechanisms of apoptosis in different cells and the role of oxidative stress and Ca2+ signalling. Particular attention is given to the different features of apoptosis in distinct cell types, ranging from hepatocytes to cardiovascular and blood cells, nervous cells or spermatozoa. Cutting-edge and user-friendly, this volume serves as a comprehensive resource for those interested in the fascinating biological processes associated to programmed cell death or apoptosis. The book is divided in two major chapter sections: general mechanisms of the apoptotic pathways and the role of oxidative stress and intracellular Ca2+ homeostasis and a more specific section dedicated to the specificities of apoptosis in a number of excitable and non-excitable cells. All of the contributions are from specialists in the field and the reviews presented, systemically examine the most exciting and innovative aspects of the apoptotic pathways in their particular areas of expertise.

Apoptosis. --- Cellular signal transduction. --- Homeostasis. --- Intracellular calcium. --- Oxidative stress. --- Apoptosis --- Oxidative stress --- Intracellular calcium --- Cellular signal transduction --- Homeostasis --- Cell Death --- Second Messenger Systems --- Ion Transport --- Physiological Processes --- Stress, Physiological --- Metabolism --- Metabolic Phenomena --- Cell Physiological Processes --- Biological Transport --- Physiological Phenomena --- Signal Transduction --- Phenomena and Processes --- Biochemical Processes --- Cell Physiological Phenomena --- Biochemical Phenomena --- Chemical Processes --- Chemical Phenomena --- Oxidative Stress --- Calcium Signaling --- Biology --- Health & Biological Sciences --- Cytology --- Cell metabolism. --- Cells --- Medicine. --- Cancer research. --- Oncology. --- Cell biology. --- Cell physiology. --- Biomedicine. --- Cancer Research. --- Cell Biology. --- Cell Physiology. --- Cell death --- Cellular control mechanisms --- Oncology  . --- Cytology. --- Cell function --- Physiology --- Cell biology --- Cellular biology --- Cytologists --- Tumors --- Cancer research

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Store-operated Ca2+ entry (SOCE) serves to control essential functions throughout the human body and represents a novel and attractive target for therapeutic intervention. This book provides an extensive overview of the role of SOCE pathways in Molecular Physiology and Cell Biology, as well as their clinical significance. (Patho)physiological principles and emerging therapeutic strategies are delineated in a way that is valuable both for the education of graduate students in advanced Cell Biology/Molecular Physiology and for the promotion of innovative research and developments in the clinical/therapeutic fields. A comprehensive, clear and elaborate representation of current concepts is provided, including a pathophysiological section arranged in a tissue/organ/system-oriented manner. The book is intended for basic researchers specializing in cell signaling, ion transport, or pharmacology, as well as biomedical scientists and clinicians with a focus on immunology, neurology or cardiology.

Nervous system -- Cytopathology. --- Nervous system -- Pathophysiology. --- Robotics in medicine. --- Calcium channels --- Cellular signal transduction --- Intracellular calcium --- Ion Transport --- Second Messenger Systems --- Biology --- Pathologic Processes --- Pathological Conditions, Signs and Symptoms --- Signal Transduction --- Biological Transport --- Biological Science Disciplines --- Cell Physiological Processes --- Biochemical Processes --- Metabolism --- Diseases --- Natural Science Disciplines --- Cell Physiological Phenomena --- Disciplines and Occupations --- Chemical Processes --- Metabolic Phenomena --- Biochemical Phenomena --- Phenomena and Processes --- Chemical Phenomena --- Calcium Signaling --- Disease --- Genetics --- Human Anatomy & Physiology --- Health & Biological Sciences --- Biophysics --- Animal Biochemistry --- Calcium channels. --- Cellular signal transduction. --- Intracellular calcium. --- Cellular calcium --- Cellular information transduction --- Information transduction, Cellular --- Signal transduction, Cellular --- Channels, Calcium --- Medicine. --- Human physiology. --- Molecular biology. --- Cardiology. --- Cell biology. --- Biomedicine. --- Molecular Medicine. --- Cell Biology. --- Human Physiology. --- Biological and Medical Physics, Biophysics. --- Calcium in the body --- Second messengers (Biochemistry) --- Bioenergetics --- Cellular control mechanisms --- Information theory in biology --- Ion channels --- Cytology. --- Heart --- Internal medicine --- Human biology --- Medical sciences --- Physiology --- Human body --- Cell biology --- Cellular biology --- Cells --- Cytologists --- Clinical sciences --- Medical profession --- Life sciences --- Pathology --- Physicians --- Health Workforce --- Biophysics. --- Biological physics. --- Biological physics --- Physics --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biomolecules --- Systems biology