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Book
Novel aspects in acute lymphoblastic leukemia
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ISBN: 9535165739 9533077530 Year: 2011 Publisher: IntechOpen

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Abstract

Acute lymphoblastic leukemia (ALL) has turned from a universally fatal to a highly curable disease in little more than four decades. Even though differences in outcome continue to exist between children and adults, intense efforts are under way to overcome this discrepancy and improve the prognosis of adult patients as well. This exemplary progress in ALL therapy has been possible by the combination of an increasingly better understanding of the biology of the disease, availability of a range of effective drugs, and astute designs and relentless executions of many clinical trials. ALL is a complex disease requiring complex therapy. Whereas this book cannot provide a comprehensive review of every one of its many facets, the chapters from many investigators from around the world nevertheless cover a number of relevant topics: aspects of the epidemiology of ALL in Hispanics, ophthalmologic manifestations of ALL, overviews of current therapy and drug-resistance mechanisms, novel biological pathways and targets, new drugs in development, and long-term consequences of CNS prophylaxis and therapy. The publishers and editor therefore hope that the prospective readers will find enough insight and information for their own endeavors.


Book
Fast Facts : Leukemia
Authors: ---
ISBN: 1910797839 1910797847 Year: 2019 Publisher: Oxford, England : Karger,

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A thorough overview of the four main types of leukemia (acute and chronic myeloid, acute lymphoblastic and chronic lymphocytic), with superb explanatory illustrations. Covering all aspects of the disease, from a detailed description of hematopoiesis and what goes wrong in leukemia, through the tests and interventions, to the management of emergency complications, this highly readable primer is the ideal resource for primary care providers, specialist nurses and oncology/hematology trainees wanting to know more.


Book
Leukemias : Updates and New Insights
Authors: ---
ISBN: 9535122029 9535172638 Year: 2015 Publisher: IntechOpen

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Abstract

Hematology has constantly been advancing in parallel with technological developments that have expanded our understanding of the phenotypic, genetic, and molecular complexity and extreme clinical and biological heterogeneity of leukemias. This in turn allowed for developing more effective and less toxic alternative therapeutic approaches directed against critical molecular pathways in leukemic cells. The continuous and rather extensive influx of new information regarding the key features and underlying mechanisms as well as treatment options of leukemias requires frequent updating of this topic. The primary objective of this book is to provide the specialists involved in the clinical management and experimental research of acute and chronic leukemias with comprehensive and concise information on some important theoretical and practical developments in the biology, clinical assessment, and treatment of patients with leukemias; on specific clinical scenarios such as pregnancy or age; as well as on some molecular and pathogenetic mechanisms and their respective translation into novel therapies.


Book
Leucemia : Desde la mutació genéica inicial hasta el apoyo para la supervivencia
Authors: ---
ISBN: 3318066346 3318066338 Year: 2020 Publisher: Abingdon, Oxford, England : S. Karger Publishers Ltd,

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Book
Fast Facts : leukemia
Authors: ---
ISBN: 3318069493 Year: 2022 Publisher: Abingdon, Oxford : S. Karger Publishers Ltd,

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"This revised and updated second edition of 'Fast Facts: Leukemia' addresses the causes and risk factors for each subtype of leukemia, the initial and confirmatory diagnostic tests, and the latest treatment options. Designed as a comprehensive primer for physician assistants, nurse practitioners, primary care providers, oncology nurses, hematology/ oncology trainees and pharmacists, this resource will help the non-specialist and those in training to identify leukemia early and provide a thorough understanding of the pathology and genetic basis of the disease, treatment options, and effective approaches to emergency and supportive care."--


Book
Leukemia : from biology to clinic
Authors: ---
ISBN: 1803569069 Year: 2023 Publisher: London : IntechOpen,

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Abstract

Medical professionals and researchers in the field of leukemias are faced with the need to continuously update their knowledge in a wide range of areas, ranging from fundamental molecular processes and mechanisms to a thorough understanding of clinical features and modern approaches to achieve maximum therapeutic results. This book does not have the ambition to present comprehensively the problems of leukemias, but it is an attempt to acquaint the audience of specialists involved in clinical management and experimental research with some modern advances and concepts in the three main directions: biology, clinical presentation and treatment. The biological aspects of the origin, development and therapy resistance of leukemias are within the scope of the first section. Comprehensive and concise information on the clinical assessment and treatment of leukemia patients is provided, as well as on some specific interdisciplinary clinical scenarios such as leukemic retinopathy, in the second section. Finally, challenges, current standards and recent advances in the therapy of acute leukemias comprise the third section of the book.


Periodical
Leukemia supplements.
ISSN: 20445229 Year: 2012 Publisher: London : Nature Pub. Group,

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Book
Leukemia
Authors: ---
ISBN: 953517150X 9535111272 Year: 2013 Publisher: IntechOpen

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Abstract

Leukemias are a group of heterogeneous neoplastic disorders, that differ significantly in terms of morhological, immunophenotypic, cytogenetic and molecular features of malignant cells. These specific features reflect the differences in the spectrum of underlying biological alterations involved in malignant transformation, and/or variations in the level of hematopoietic stem cells hierarchy where the transforming events occur. The continuous and rather extensive influx of new information regarding the pathogenesis and treatment of leukemias requires a frequent updating of this topic. The primary objective of this book is to provide the specialists involved in the diagnosis and management of acute and chronic leukemias with a comprehensive and concise information on some important theoretical and practical issues of the biology and clinical presentation, the diagnosis, treatment and follow up of patients with leukemias.


Book
Vladkyne vsech nemoci : Pribeh rakoviny
Author:
ISBN: 8021085991 9788021085992 9788021077614 Year: 2015 Publisher: Brno, [Czech Republic] : Masarykova Univerzita,

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Book
Hematologic Malignancies: Acute Leukemias
Authors: ---
ISBN: 3540723048 3540723021 364242080X Year: 2008 Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer,

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Better therapy of acute leukemias depends ultimately on better understanding of the distinction between leukemic and normal progenitor cells. Thus, several chapters in this volume describe current knowledge of acute leukemia biology and discuss new classification systems that have arisen consequent to emerging insights into pathogenesis. Treatment has also improved for particular types of acute leukemia. Given our intention that the book be useful to clinicians, we pay particular attention to these advances, to management of acute leukemia in general, and to development of new therapies.

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