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Book
Bioinformatics
Authors: ---
ISBN: 9535156985 9535108786 Year: 2012 Publisher: IntechOpen

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Abstract

This book is divided into different research areas relevant in Bioinformatics such as biological networks, next generation sequencing, high performance computing, molecular modeling, structural bioinformatics, molecular modeling and intelligent data analysis. Each book section introduces the basic concepts and then explains its application to problems of great relevance, so both novice and expert readers can benefit from the information and research works presented here.


Book
Systems and Computational Biology : Molecular and Cellular Experimental Systems
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ISBN: 9535155474 9533072806 Year: 2011 Publisher: IntechOpen

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Abstract

Whereas some "microarray" or "bioinformatics" scientists among us may have been criticized as doing "cataloging research", the majority of us believe that we are sincerely exploring new scientific and technological systems to benefit human health, human food and animal feed production, and environmental protections. Indeed, we are humbled by the complexity, extent and beauty of cross-talks in various biological systems; on the other hand, we are becoming more educated and are able to start addressing honestly and skillfully the various important issues concerning translational medicine, global agriculture, and the environment. The two volumes of this book presents a series of high-quality research or review articles in a timely fashion to this emerging research field of our scientific community.


Book
New developments in biomedical engineering
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ISBN: 9535164139 9537619575 Year: 2010 Publisher: IntechOpen

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Biomedical Engineering is a highly interdisciplinary and well established discipline spanning across engineering, medicine and biology. A single definition of Biomedical Engineering is hardly unanimously accepted but it is often easier to identify what activities are included in it. This volume collects works on recent advances in Biomedical Engineering and provides a bird-view on a very broad field, ranging from purely theoretical frameworks to clinical applications and from diagnosis to treatment.


Book
Mobile health technologies : theories and applications
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ISBN: 9535126350 9535173049 9535126342 Year: 2016 Publisher: IntechOpen

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Mobile Health Technologies, also known as mHealth technologies, have emerged, amongst healthcare providers, as the ultimate Technologies-of-Choice for the 21st century in delivering not only transformative change in healthcare delivery, but also critical health information to different communities of practice in integrated healthcare information systems. mHealth technologies nurture seamless platforms and pragmatic tools for managing pertinent health information across the continuum of different healthcare providers. mHealth technologies commonly utilize mobile medical devices, monitoring and wireless devices, and/or telemedicine in healthcare delivery and health research. Today, mHealth technologies provide opportunities to record and monitor conditions of patients with chronic diseases such as asthma, Chronic Obstructive Pulmonary Diseases (COPD) and diabetes mellitus. The intent of this book is to enlighten readers about the theories and applications of mHealth technologies in the healthcare domain.


Book
Medical Informatics
Authors: ---
ISBN: 9535168886 9535102591 Year: 2012 Publisher: IntechOpen

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Information technology has been revolutionizing the everyday life of the common man, while medical science has been making rapid strides in understanding disease mechanisms, developing diagnostic techniques and effecting successful treatment regimen, even for those cases which would have been classified as a poor prognosis a decade earlier. The confluence of information technology and biomedicine has brought into its ambit additional dimensions of computerized databases for patient conditions, revolutionizing the way health care and patient information is recorded, processed, interpreted and utilized for improving the quality of life. This book consists of seven chapters dealing with the three primary issues of medical information acquisition from a patient's and health care professional's perspective, translational approaches from a researcher's point of view, and finally the application potential as required by the clinicians/physician. The book covers modern issues in Information Technology, Bioinformatics Methods and Clinical Applications. The chapters describe the basic process of acquisition of information in a health system, recent technological developments in biomedicine and the realistic evaluation of medical informatics.


Book
Computational biology and applied bioinformatics
Authors: --- ---
ISBN: 953515544X 9533076291 Year: 2011 Publisher: IntechOpen

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Abstract

Nowadays it is difficult to imagine an area of knowledge that can continue developing without the use of computers and informatics. It is not different with biology, that has seen an unpredictable growth in recent decades, with the rise of a new discipline, bioinformatics, bringing together molecular biology, biotechnology and information technology. More recently, the development of high throughput techniques, such as microarray, mass spectrometry and DNA sequencing, has increased the need of computational support to collect, store, retrieve, analyze, and correlate huge data sets of complex information. On the other hand, the growth of the computational power for processing and storage has also increased the necessity for deeper knowledge in the field. The development of bioinformatics has allowed now the emergence of systems biology, the study of the interactions between the components of a biological system, and how these interactions give rise to the function and behavior of a living being. This book presents some theoretical issues, reviews, and a variety of bioinformatics applications. For better understanding, the chapters were grouped in two parts. In Part I, the chapters are more oriented towards literature review and theoretical issues. Part II consists of application-oriented chapters that report case studies in which a specific biological problem is treated with bioinformatics tools.


Book
Selected Works in Bioinformatics
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ISBN: 9535155482 9533072814 Year: 2011 Publisher: IntechOpen

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This book consists of nine chapters covering a variety of bioinformatics subjects, ranging from database resources for protein allergens, unravelling genetic determinants of complex disorders, characterization and prediction of regulatory motifs, computational methods for identifying the best classifiers and key disease genes in large-scale transcriptomic and proteomic experiments, functional characterization of inherently unfolded proteins/regions, protein interaction networks and flexible protein-protein docking. The computational algorithms are in general presented in a way that is accessible to advanced undergraduate students, graduate students and researchers in molecular biology and genetics. The book should also serve as stepping stones for mathematicians, biostatisticians, and computational scientists to cross their academic boundaries into the dynamic and ever-expanding field of bioinformatics.


Book
Advanced Biosignal Processing and Diagnostic Methods
Authors: ---
ISBN: 9535125206 9535154419 9535125192 Year: 2016 Publisher: IntechOpen

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Personal health and well-being was and is important for all individuals. This includes the way people are living, what they do to stay healthy as well as a profound, well-informed diagnosis and appropriate treatment in case of disease. To achieve these goals, modern medicine is provided with a large variety of tools to assess a patient's health state and collect the information required for a proper diagnosis and treatment, which is tailored to the patient's needs. Many of these available tools use signals either generated by the human body, for example, electroencephalogram (EEG) and electrocardiogram (ECG), or by interacting with the human body while traversing it like microwaves or reflected visible light that is recorded by a video camera. The biosignals recorded by the available and newly developed methods have to be processed to extract the information about the patient's condition and, analyzed tissue and cells. This book presents a small selection of the recent developments in the field of biosignal processing. The covered diagnostic tools and methods include the assessment of respiratory state through gait analysis, the contactless monitoring of cardiovascular and respiratory parameters using microwaves, a non-linear approach to extract the fetal ECG from non-invasive abdominal recordings, identification of epileptic networks from pre-surgical neurophysiological recordings and an improved method to obtain and validate the copy number alterations parameter, which are considered an important marker in cancer classification.


Book
Bioinformatics Tools for Detection and Clinical Interpretation of Genomic Variations
Authors: ---
ISBN: 1789238005 1838818448 1789237998 Year: 2019 Publisher: IntechOpen

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Genomic variations and phenotypic diversity are closely linked and form the underlying mechanism for development of many human diseases. This book addresses the methods of detection, analysis, and interpretation of genomic variations in clinically relevant scenarios. If your research or clinical practice involves handling of genomic sequencing data, this book is for you. Topics covered include: methods for identifying genetic diversity, the workflow for analyzing whole exome and whole genome sequencing data, local ancestry deconvolution models, the value of molecular patterns and pattern biomarkers in cancer diagnosis and prognosis, and genotyping and profiling resistance-associated variants of hepatitis C. If your research or clinical practice involves handling of genomic sequencing data, this book is for you.


Book
Independent Component Analysis for Audio and Biosignal Applications
Authors: ---
ISBN: 9535162454 9535107828 Year: 2012 Publisher: IntechOpen

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Independent Component Analysis (ICA) is a signal-processing method to extract independent sources given only observed data that are mixtures of the unknown sources. Recently, Blind Source Separation (BSS) by ICA has received considerable attention because of its potential signal-processing applications such as speech enhancement systems, image processing, telecommunications, medical signal processing and several data mining issues. This book brings the state-of-the-art of some of the most important current research of ICA related to Audio and Biomedical signal processing applications. The book is partly a textbook and partly a monograph. It is a textbook because it gives a detailed introduction to ICA applications. It is simultaneously a monograph because it presents several new results, concepts and further developments, which are brought together and published in the book.

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