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Proteomics is a multifaceted, interdisciplinary field which studies the complexity and dynamics of proteins in biological systems. It combines powerful separation and analytical technology with advanced informatics to understand the function of proteins in the cell and in the body. This book provides a clear conceptual description of each facet of proteomics, describes recent advances in technology and thinking in each area, and provides details of how these have been applied to a variety of biological problems. It is written by expert practitioners in the field, from industry, research institutions, and the clinic. It provides junior and experienced researchers with an invaluable proteomic reference, and gives fascinating glimpses of the future of this dynamic field.
Proteomics --- Proteins --- Post-translational modification. --- Protéomique --- Protéines --- Protéines --- Databases. --- Bases de données --- Modification post-traductionnelle --- EPUB-LIV-FT LIVBIOLO SPRINGER-B
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Recent developments have revealed that proteins can undergo a diverse range of modifications by lipids which can dramatically effect their structural and functional properties. These modifications include acylation, isoprenylation, and the attachment of glycolipid. Written by acknowledged experts in the field, this unique guide describes the latest biochemical, cell biological, and molecular biological techniques being used in this rapidly expanding area. The book discusses lipid modifications of proteins which play important roles in cellular signalling, protein targeting and cellular growth and differentiation. Detailed protocols are provided for all the key techniques, and the relevant background material is included. The book will be an essential manual for a wide range of scientists studying the modification of protein by lipids, including membrane and protein biochemists, cell biologists, immunologists, bacteriologists, parasitologists, and virologists.
Analytical biochemistry --- Lipoproteins --- Protein Processing, Post-Translational --- Acylation --- Post-translational modification --- Protéines --- chemical synthesis --- Synthesis --- Research --- Methodology --- Modification post-traductionnelle --- Post-translational modification. --- Acylation. --- Methodology. --- Protéines --- Protein Processing, Post-Translational. --- chemical synthesis. --- Co-translational modification --- Cotranslational modification --- Modification, Post-translational --- Post-translation protein modification --- Post-translational protein modification --- Posttranslation protein modification --- Posttranslational modification --- Posttranslational protein modification --- Genetic translation --- Proteins --- Lipids --- Chemical reactions --- Synthesis&delete& --- Research&delete& --- Lipoproteins - Synthesis - Research - Methodology.
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Proteomics. --- Proteins --- Post-translational modification. --- Databases. --- 577.112 --- 577.218 --- 57.088 --- 57.088 Special methods and techniques for studing biological molecules. Separation. Centrifuging. X-ray study. Radioisotope methods --- Special methods and techniques for studing biological molecules. Separation. Centrifuging. X-ray study. Radioisotope methods --- 577.218 Molecular mechanisms of control : gene expression. Molecular embryology --- Molecular mechanisms of control : gene expression. Molecular embryology --- 577.112 Proteins --- Protéines --- Analysis. --- Analyse --- Bases de données --- Modification post-traductionnelle --- Post-translational modification --- Proteomics --- Molecular biology --- Proteids --- Biomolecules --- Polypeptides --- Co-translational modification --- Cotranslational modification --- Modification, Post-translational --- Post-translation protein modification --- Post-translational protein modification --- Posttranslation protein modification --- Posttranslational modification --- Posttranslational protein modification --- Genetic translation --- Databases --- Synthesis --- Cell biology. --- Biochemistry. --- Human genetics. --- Molecular biology. --- Cancer research. --- Cell Biology. --- Biochemistry, general. --- Human Genetics. --- Molecular Medicine. --- Cancer Research. --- Cancer research --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Systems biology --- Genetics --- Heredity, Human --- Human biology --- Physical anthropology --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medical sciences --- Cell biology --- Cellular biology --- Cells --- Composition --- Proteins - Databases
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