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This volume looks at the methodology and techniques used by experts to study how certain molecules function in specific locations, and their temporal patterns. Chapters in this book cover topics such as in vivo single-molecule tracking of voltage-gated calcium channels with split-fluorescent proteins in CRISPR-engineering C. elegans; protein-protein interactions in membranes using single particle tracking; neuropathological diseases revealed by quantum-dot single particle tracking; SPoD-OnSPAN; and investigating molecular diffusion inside small neuronal compartments with two-photon fluorescence correlation spectroscopy. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and comprehensive, Single Molecule Microscopy is a valuable resource for any researcher interested in learning more about this important field. .
Biomolècules --- Microscòpia mèdica --- Neurobiologia molecular --- Neurologia molecular --- Biologia molecular --- Neurobiologia --- Microscòpia clínica --- Microscopis en medicina --- Diagnòstic de laboratori --- Microscòpia --- Microcirurgia --- Molècules biològiques --- Molècules --- Àcids nucleics --- Biopolímers --- Metabòlits --- Proteïnes --- Neurosciences. --- Biophysics. --- Neuroscience. --- Bioanalysis and Bioimaging. --- Biological physics --- Biology --- Medical sciences --- Physics --- Neural sciences --- Neurological sciences --- Neuroscience --- Nervous system
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RNA. --- DNA damage. --- Ribonucleic acid --- Ribose nucleic acid --- Nucleic acids --- Ribose --- Damage, DNA --- Biochemical genetics --- Mutation (Biology) --- ADN --- Reparació de l'ADN --- Biomolècules --- Procariotes --- Microorganismes --- Cianobacteris --- Molècules biològiques --- Molècules --- Àcids nucleics --- Biopolímers --- Metabòlits --- Proteïnes --- Biologia molecular --- Mecanismes de reparació de l'àcid desoxiribonucleic --- Reparació de l'àcid desoxiribonucleic --- Genètica bioquímica --- Medicaments antineoplàstics --- Àcid desoxiribonucleic --- DNA --- ADN fòssil --- ADN recombinant --- Elements genètics mòbils --- Gens
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Bioactive compounds. --- Biologically active compounds --- Compounds, Bioactive --- Compounds, Biologically active --- Compounds, Physiologically active --- Physiologically active compounds --- Chemicals --- Membranes (Biologia) --- Biotecnologia --- Biomolècules --- Molècules biològiques --- Molècules --- Àcids nucleics --- Biopolímers --- Metabòlits --- Proteïnes --- Biologia molecular --- Biologia --- Enginyeria --- Antropometria --- Biosíntesi --- Biotecnologia agrícola --- Biotecnologia alimentària --- Biotecnologia farmacèutica --- Biotecnologia marina --- Biotecnologia microbiana --- Enginyeria bioquímica --- Enginyeria sanitària --- Ergonomia --- Indústries biotecnològiques --- Microbiologia industrial --- Reproducció assistida --- Bioreactors --- Interfícies biològiques --- Protoplasma --- Liposomes --- Membrana mucosa --- Membranes cel·lulars --- Membranes lipídiques --- Periosti --- Peritoneu --- Proteïnes de membrana
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Volume 323 of Methods in Enzymology is dedicated to the energetics of biological macromolecules. Understanding the molecular mechanisms underlying a biological process requires detailed knowledge of the structural relationships within the system and an equally detailed understanding of the energetic driving forces that control the structural interactions. This volume presents modern thermodynamic techniques currently being utilized to study the energetic driving forces in biological systems. It will be a useful reference source and textbook for scientists and students whose goal
Bio-energetica --- Bioenergetics --- Biological molecules --- Biologische moleculen --- Biomoleculen --- Biomolecules --- Biomolécules --- Bioénergétique --- Dynamica [Thermo] --- Dynamique [Thermo] --- Energetica [Bio-] --- Energie biologique --- Energy [Biological ] --- Energy balance (Biology) --- Energy budget (Biology) --- Energy dynamics (Ecology) --- Energy utilization (Biology) --- Macromoleculen --- Macromolecules --- Macromolécules --- Moleculen [Bio] --- Moleculen [Biologische ] --- Moleculen [Macro] --- Molecules [Biological ] --- Molécules [Macro] --- Molécules biologiques --- Thermodynamica --- Thermodynamics --- Thermodynamique --- Allosteric regulation. --- Bioenergetics. --- Energy Metabolism. --- Macromolecular Systems. --- Macromolecules. --- Molecular Conformation. --- Thermodynamics. --- Human Anatomy & Physiology --- Health & Biological Sciences --- Animal Biochemistry --- Chemistry, Physical and theoretical --- Dynamics --- Mechanics --- Physics --- Heat --- Heat-engines --- Quantum theory --- Biochemistry --- Energy budget (Geophysics) --- Molecules --- Supramolecular chemistry --- Enzymology --- Macromolecular Systems --- Allosteric Regulation. --- Macromolécules --- Bioénergétique --- Molecular biology --- ENERGY METABOLISM --- MOLECULAR ASSOCIATION --- PROTEINS --- THERMODYNAMICS --- CONFORMATION --- REACTIONS
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This book provides a comprehensive overview of the latest research on the molecular players in the tumor microenvironment, including Cathepsin D, galectins, iron, oxygen, Phospholipase D1, leptin, extracellular vesicles, and more. Taken alongside its companion volumes, these books update us on what we know about the tumor microenvironment as well as future directions. Tumor Microenvironment: Molecular Players – Part A is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.
Protocols --- Tumors --- Cancer --- Molecular aspects. --- Neoplasms --- Tumours --- Pathology --- Cysts (Pathology) --- Oncology --- Cell biology. --- Cancer research. --- Oncology . --- Cell Biology. --- Cancer Research. --- Oncology. --- Cancer research --- Cell biology --- Cellular biology --- Biology --- Cells --- Càncer --- Biomolècules --- Molècules biològiques --- Molècules --- Àcids nucleics --- Biopolímers --- Metabòlits --- Proteïnes --- Biologia molecular --- Carcinoma --- Carcinosi --- Càncer d'ossos --- Càncer de cap --- Càncer de coll --- Càncer de bufeta --- Càncer de fetge --- Càncer de laringe --- Càncer de mama --- Càncer de pàncrees --- Càncer de pell --- Càncer de pròstata --- Càncer de pulmó --- Càncer de ronyó --- Càncer de tiroide --- Càncer d'ovari --- Càncer gastrointestinal --- Càncer ginecològic --- Càncer en els adolescents --- Càncer en els infants --- Medicaments antineoplàstics --- Melanoma --- Leucèmia --- Sarcoma --- Carcinògens --- Cèl·lules canceroses --- Cirurgia oncològica --- Infermeria oncològica --- Malalts de càncer --- Metàstasi --- Oncologia --- Carcinomes --- Malalties neoplàstiques --- Neoplàsies --- Neoplasmes --- Patologia --- Feocromocitoma --- Fibromes --- Marcadors tumorals --- Mesotelioma --- Miomes --- Pòlips (Patologia) --- Sarcoïdosi --- Teratoma --- Tumors de parts toves --- Tumors en els animals --- Classificació de tumors --- Quistos
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This book provides a state-of-the-art compendium on the role of proteoglycans and glycosaminoglycans during development and in cancer. It also suggests directions for novel therapeutic and biotechnological applications in stem cell biology. Proteoglycans and glycosaminoglycans, as part of the extracellular matrix, are multifunctional modulators of growth factor, cytokine, integrin and morphogen signaling, which determine both self-renewal, senescence and/or differentiation of stem cells during development. Since proteoglycans modulate cell adhesion and migration they are important organizers of the extracellular matrix within the proper stem cell niche. A malfunctioning of proteoglycans and glycosaminoglycans contributes to the cancer stem cell phenotype, which is linked to therapeutic resistance and recurrence in malignant disease. This book is essential reading for anyone interested in the extracellular matrix and its role in development. The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology.
Developmental biology. --- Cancer research. --- Human physiology. --- Analytical chemistry. --- Developmental Biology. --- Cancer Research. --- Human Physiology. --- Analytical Chemistry. --- Analysis, Chemical --- Analytic chemistry --- Chemical analysis --- Chemistry, Analytic --- Chemistry --- Human biology --- Medical sciences --- Physiology --- Human body --- Cancer research --- Development (Biology) --- Biology --- Growth --- Ontogeny --- Proteoglycans. --- Glycosaminoglycans. --- Stem cells. --- Colony-forming units (Cells) --- Mother cells --- Progenitor cells --- Cells --- Mucopolysaccharides --- Glycoproteins --- Stem Cells. --- Proteoglycans --- Proteoglycan --- Proteoglycan Type H --- Colony-Forming Unit --- Colony-Forming Units --- Mother Cells --- Progenitor Cells --- Cell, Mother --- Cell, Progenitor --- Cell, Stem --- Cells, Mother --- Cells, Progenitor --- Cells, Stem --- Colony Forming Unit --- Colony Forming Units --- Mother Cell --- Progenitor Cell --- Stem Cell --- Cell Self Renewal --- Stem Cell Research --- Glicoproteïnes --- Biomolècules --- Cèl·lules mare --- Cèl·lules --- Cèl·lules mare embrionàries --- Molècules biològiques --- Molècules --- Àcids nucleics --- Biopolímers --- Metabòlits --- Proteïnes --- Biologia molecular --- Glucoprotèids --- Glucoproteïnes --- Glicoconjugats --- Antígens CD --- Integrines --- Interferó --- Laminina --- Mucoproteïnes
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