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In the Paradiso, Dante attempts to emphasize the heightened tension between the limits of human language and the need to put into words a content that deals with divine ineffability. It is a content-stuff that is not codified, and Dante is faced with the problem of narrating his experience that is not comprehensible to humans. The author will analyze those multimodal linguistic and non-linguistic strategies Dante utilizes to allow the reader to gain an idea of his ineffable journey in the afterlife precisely through his Florentine vernacular.

Multimorbidity.

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One of the main challenges in the healthcare sector in recent years has concerned the effort to ensure the healthcare sustainability in view of demographic change. Due to the progressive increasing of aging and chronic conditions, it is necessary to employ treatment methods with increasingly advanced and costly technological and care requirements that the Italian Health System has to deal with both from a health and economic standpoint. This critical issue also emerged during the COVID-19 pandemic, proving the need to reconsider the management of chronic conditions, which is still too focused on a specialist and/or hospital perspective, to make it more suitable for responding to patients' care issues while respecting available economic resources. In this regard, Outcome Research is of great interest as a research area based on Real World Evidences (RWE). Indeed, analyses of evidence produced in a Real-World context can confirm or not the value of political decision-making to improve governance and the quality of health-services provided.The aim of this work is to provide a detailed snapshot of the prevalence of chronic diseases and related comorbidities in Campania Region. At the same time, it also aims to be an effective knowledge tool for decision-makers involved in the planning of health policies and strategies. Una delle sfide che ha maggiormente segnato il dibattito pubblico degli ultimi anni ha riguardato lo sforzo di salvaguardare la sostenibilità dell’assistenza sanitaria in relazione al cambiamento demografico. Il progressivo invecchiamento della popolazione, nonché la tendenziale cronicizzazione delle malattie, richiede l’impiego di metodiche di cura con requisiti tecnologici-assistenziali sempre più avanzati e costosi, che in Italia gravano e mettono in difficoltà, sia da un punto di vista sanitario sia economico, il Sistema Sanitario Nazionale. Tale criticità è emersa anche durante la pandemia da COVID-19, comprovando la necessità di ripensare al modello di gestione della cronicità, ancora troppo centrato su una prospettiva specialistica e/o ospedaliera, per renderlo più idoneo a rispondere alle problematiche assistenziali dei pazienti nel rispetto delle risorse economiche disponibili. A questo proposito, può risultare di grande interesse l’Outcome Research, intesa come area di ricerca che si avvale della Real World Evidence (RWE), poiché dalle analisi delle evidenze prodotte nel mondo reale è possibile confermare o meno la validità delle decisioni politiche attuate al fine di migliorare la governance e la qualità dei servizi erogati.Questo lavoro intende proporre una fotografia dettagliata della prevalenza delle patologie croniche, e delle relative comorbidità, in Regione Campania ma, nel contempo, vuole anche essere un efficace strumento di conoscenze a disposizione di quei decisori impegnati nella programmazione delle politiche e delle strategie sanitarie.

Medicine --- Chronic conditions, Comorbidity, RWE, Multimorbidity clusters

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One of the main challenges in the healthcare sector in recent years has concerned the effort to ensure the healthcare sustainability in view of demographic change. Due to the progressive increasing of aging and chronic conditions, it is necessary to employ treatment methods with increasingly advanced and costly technological and care requirements that the Italian Health System has to deal with both from a health and economic standpoint. This critical issue also emerged during the COVID-19 pandemic, proving the need to reconsider the management of chronic conditions, which is still too focused on a specialist and/or hospital perspective, to make it more suitable for responding to patients' care issues while respecting available economic resources. In this regard, Outcome Research is of great interest as a research area based on Real World Evidences (RWE). Indeed, analyses of evidence produced in a Real-World context can confirm or not the value of political decision-making to improve governance and the quality of health-services provided.The aim of this work is to provide a detailed snapshot of the prevalence of chronic diseases and related comorbidities in Campania Region. At the same time, it also aims to be an effective knowledge tool for decision-makers involved in the planning of health policies and strategies. Una delle sfide che ha maggiormente segnato il dibattito pubblico degli ultimi anni ha riguardato lo sforzo di salvaguardare la sostenibilità dell’assistenza sanitaria in relazione al cambiamento demografico. Il progressivo invecchiamento della popolazione, nonché la tendenziale cronicizzazione delle malattie, richiede l’impiego di metodiche di cura con requisiti tecnologici-assistenziali sempre più avanzati e costosi, che in Italia gravano e mettono in difficoltà, sia da un punto di vista sanitario sia economico, il Sistema Sanitario Nazionale. Tale criticità è emersa anche durante la pandemia da COVID-19, comprovando la necessità di ripensare al modello di gestione della cronicità, ancora troppo centrato su una prospettiva specialistica e/o ospedaliera, per renderlo più idoneo a rispondere alle problematiche assistenziali dei pazienti nel rispetto delle risorse economiche disponibili. A questo proposito, può risultare di grande interesse l’Outcome Research, intesa come area di ricerca che si avvale della Real World Evidence (RWE), poiché dalle analisi delle evidenze prodotte nel mondo reale è possibile confermare o meno la validità delle decisioni politiche attuate al fine di migliorare la governance e la qualità dei servizi erogati.Questo lavoro intende proporre una fotografia dettagliata della prevalenza delle patologie croniche, e delle relative comorbidità, in Regione Campania ma, nel contempo, vuole anche essere un efficace strumento di conoscenze a disposizione di quei decisori impegnati nella programmazione delle politiche e delle strategie sanitarie.

Chronic conditions, Comorbidity, RWE, Multimorbidity clusters

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

Medicine --- Psychiatry --- Exercise --- physical activity --- Diet --- nutrition --- Sleep --- fitness --- physical health --- multimorbidity --- Digital technology --- smartphone

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Chronic diseases --- Comorbidity --- Primary health care --- Chronic Disease --- Chronic diseases. --- Comorbidity. --- Primary health care. --- PHC (Primary health care) --- Coexisting disease --- Coexisting illness --- Diseases, Chronic --- NCDs (Noncommunicable diseases) --- Non-communicable diseases --- Non-infectious diseases --- Noncommunicable diseases --- Chronically Ill --- Chronic Illness --- Chronic Diseases --- Chronic Illnesses --- Disease, Chronic --- Illness, Chronic --- Illnesses, Chronic --- Multimorbidity --- Comorbidities --- Multimorbidities --- Chronic Disease. --- comorbidity --- multimorbidity --- multiple chronic conditions --- Community health services --- Epidemiology --- Diseases --- Pain Management --- Human medicine