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Oxytocin is a nonapeptide hormone with a central role in the regulation of parturition and lactation. Oxytocin receptors can be found in many tissues in humans. Oxytocin exerts a direct as well as an indirect effect on metabolism and energy balance. Considering the positive effects of oxytocin on the brain and the reproductive, immune, and autonomic nervous systems, it shows promise as a future treatment agent for anxiety, autism, personality disorders, and neurodegenerative disorders. This book focuses on oxytocin and health from the aspects of molecular and structure activity, physiological and pathological functions, and clinical applications.
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"Oxytocin is a neurohypophysial hormone that consists of nine amino acids which are synthesized in the paraventricular, supraoptic, and accessory nuclei of the hypothalamus. Oxytocin is released in systemic blood circulation through the posterior pituitary gland, where it acts as hormone, regulating a range of physiological functions. It is involved in learning and memory, sensory and motor regulation via the spinal cord and regulation of the reproductive system. The quality and stability of one's romantic relationship can impact overall well-being and health, leading researchers to search for the mechanisms that underlie the development of relationship discord versus those that foster satisfaction. Within this field, there has been recent attention towards biological variables, with oxytocin being at the forefront due to its established role in pair bonding in both animals and humans. A review is presented which suggests the involvement of the oxitocinergic system in the regulation of the hypothalamic-pituitary-gonadal-axis during pubertal development and social cognition in mammals. The closing study presents data which indicate that oxytocin has actions in different brain areas and is involved with spine-specific plastic effects, and modulates the dynamic neural sex steroid actions and the processing of context-dependent stimuli by adapting the neuronal and synaptic structure to the reproductive status and the social experience in mice"--
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Oxytocin is a nonapeptide hormone with a central role in the regulation of parturition and lactation. Oxytocin receptors can be found in many tissues in humans. Oxytocin exerts a direct as well as an indirect effect on metabolism and energy balance. Considering the positive effects of oxytocin on the brain and the reproductive, immune, and autonomic nervous systems, it shows promise as a future treatment agent for anxiety, autism, personality disorders, and neurodegenerative disorders. This book focuses on oxytocin and health from the aspects of molecular and structure activity, physiological and pathological functions, and clinical applications.
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Oxytocin is a nonapeptide hormone with a central role in the regulation of parturition and lactation. Oxytocin receptors can be found in many tissues in humans. Oxytocin exerts a direct as well as an indirect effect on metabolism and energy balance. Considering the positive effects of oxytocin on the brain and the reproductive, immune, and autonomic nervous systems, it shows promise as a future treatment agent for anxiety, autism, personality disorders, and neurodegenerative disorders. This book focuses on oxytocin and health from the aspects of molecular and structure activity, physiological and pathological functions, and clinical applications.
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Oxytocin --- Congresses --- Oxytocin - Congresses.
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Brain. --- Oxytocin. --- Oxytocin. --- Vasopressin. --- Vasopressins.
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This publication by the World Health Organization provides regulatory guidance for the assessment and management of applications for marketing authorization of oxytocin products. It addresses issues related to the quality of oxytocin, particularly in low and middle-income countries, where inferior quality products can lead to serious medical consequences, such as postpartum hemorrhage. The document outlines the technical information, stability, degradation, and production factors impacting oxytocin manufacturing. It is intended for healthcare authorities and stakeholders involved in pharmaceutical regulation, offering insights into ensuring the availability of high-quality oxytocin as a critical medication for maternal health.
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This publication by the World Health Organization (WHO) provides regulatory guidance for the assessment and management of applications for marketing authorization of oxytocin. It addresses quality issues related to oxytocin, a critical uterotonic used to manage postpartum hemorrhage, a leading cause of maternal mortality in low- and middle-income countries. The book outlines the consequences of substandard oxytocin, causes of quality issues, and emphasizes the importance of proper storage to maintain efficacy. It targets national medicines regulatory authorities, procurement agents, and health program leaders, aiming to ensure the availability of safe and effective oxytocin products in the market.
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Depuis les années 1950, le développement des plastiques a bouleversé l'histoire de la médecine. Les anesthésistes administraient autrefois des médicaments par inhalation. De nos jours, ils le font par l'intermédiaire de cathéters en plastique, en particulier par voies intraveineuse et péridurale. Aujourd'hui, la femme en travail a en général le bras relié à un sac en plastique par un tube en plastique, et un cathéter en plastique est introduit dans sa colonne vertébrale. Les plastiques ont transformé les disciplines médicales et permis l'émergence de nouveaux concepts médicaux, comme les unités de soins intensifs, et de nouvelles spécialités, comme la néonatologie. Analysant l'influence de la révolution des plastiques sur l'obstétrique, l'auteur pose des questions cruciales pour la naissance d'aujourd'hui et de demain, et démontre que nous sommes à un tournant de l'histoire de la naissance, mais aussi de l'humanité. Des composés chimiques nouveaux contenus dans les plastiques s'infiltrent dans l'organisme des individus, influençant leur développement… et celui de leurs descendants. L'ocytocine synthétique injectée en routine aux parturientes se substitue à l'ocytocine naturelle, véritable hormone de l'amour impliquée dans tous les aspects de la vie sociale, affective et sexuelle, et ce à une phase critique pour le développement du bébé et du lien mère-enfant. Quel est donc l'avenir d'une civilisation née sous ocytocine synthétique, privée de la libération d'un abondant flot d'hormones de l'amour au cours de périodes critiques de la vie humaine ? Comment créer les conditions optimales pour des accouchements naturels faciles et rapides, afin de rendre au système de l'ocytocine naturelle toute son utilité et de le préserver d'une dégénérescence progressive qui peut sembler inéluctable ? L'enjeu n'est rien de moins que notre aptitude, et plus encore celle de nos arrière-petits-enfants, à tisser des liens avec les autres membres de notre espèce.
Plastics --- Parturition --- Oxytocin --- Labor Pain
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