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This book, now published in its second edition, covers a wide range of topics relating to the use of radiopharmaceuticals. The basics of nuclear chemistry, radiochemistry, and radiopharmacology are considered in detail, regulatory issues are reviewed, and potential applications in drug development, translational medicine, clinical diagnostics, and targeted therapy are discussed. Compared with the first edition, the chapters on targeted therapy with alpha- and beta-emitting radiopharmaceuticals and theranostics are completely new. Other chapters have been updated and revised as necessary. Radioisotope-based molecular imaging probes (radiopharmaceuticals) provide unprecedented insights into biochemistry and function in both normal and diseased states of living systems, with unbiased in vivo measurements of regional radiotracer activities offering very high specificity and sensitivity. No other molecular imaging technology, including functional magnetic resonance imaging, can provide such high sensitivity and specificity at a tracer level. This book, written by an experienced radiochemist and scientist, offers valuable insights into the full range of applications of this technology.

Nuclear medicine. --- Oncology. --- Neurology. --- Nuclear Medicine. --- Medicine --- Nervous system --- Neuropsychiatry --- Tumors --- Atomic medicine --- Radioisotopes in medicine --- Medical radiology --- Radioactive tracers --- Radioactivity --- Diseases --- Physiological effect --- Diagnostic imaging. --- Molecular diagnosis. --- Radiopharmaceuticals. --- Tomography, Emission. --- Computerized emission tomography --- Emission tomography --- PET (Tomography) --- PET-CT (Tomography) --- Positron emission tomography --- Positron emission transaxial tomography --- Radionuclide tomography --- Scintigraphy, Tomographic --- Tomography, Radionuclide --- Diagnosis --- Diagnostic imaging --- Positrons --- Radioisotope scanning --- Radiopharmaceutical agents --- Pharmacology --- Molecular diagnostics --- Molecular biology --- Clinical imaging --- Imaging, Diagnostic --- Medical diagnostic imaging --- Medical imaging --- Noninvasive medical imaging --- Diagnosis, Noninvasive --- Imaging systems in medicine --- Data processing --- Emission --- Molecular aspects --- Molecular Imaging. --- Radiotherapy. --- Radionuclide Imaging. --- Positron-Emission Tomography. --- PET Imaging --- PET Scan --- Positron-Emission Tomography Imaging --- Tomography, Positron-Emission --- Imaging, PET --- Imaging, Positron-Emission Tomography --- PET Imagings --- PET Scans --- Positron Emission Tomography --- Positron Emission Tomography Imaging --- Positron-Emission Tomography Imagings --- Scan, PET --- Tomography Imaging, Positron-Emission --- Tomography, Positron Emission --- Gamma Camera Imaging --- Radioisotope Scanning --- Scanning, Radioisotope --- Scintigraphy --- Scintiphotography --- Imaging, Gamma Camera --- Imaging, Radionuclide --- Radiation Therapy --- Radiation Therapy, Targeted --- Radiation Treatment --- Targeted Radiation Therapy --- Radiotherapy, Targeted --- Targeted Radiotherapy --- Radiation Therapies --- Radiation Therapies, Targeted --- Radiation Treatments --- Radiotherapies --- Radiotherapies, Targeted --- Targeted Radiation Therapies --- Targeted Radiotherapies --- Therapies, Radiation --- Therapies, Targeted Radiation --- Therapy, Radiation --- Therapy, Targeted Radiation --- Treatment, Radiation --- Disease --- Radiation --- Imaging, Molecular --- Radiopharmaceutical --- radiotherapy --- therapeutic use

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This brand new book discusses the most relevant technique or combination thereof for each disease and provides guidance on which modality to use -It is a disease oriented reference meant for interpreting integrated imaging studies. While it focuses on PET-CT and SPECT-CT, it also integrates PET-MR were applicable. Features: Allows clinical hybrid imaging users to compare modalities and decide whether to use PET/CT, PET/MR or SPECT/CT to solve a clinical question. Focus on clinical applications sans technological & radiopharmaceutical details. Inclusion of emerging field of PET/MR. New PART III on workflow and normal scans with various clinical tracers. Only book that incorporates PET/MR in a systematic way.

Tomography, Emission-Computed --- Investigative Techniques --- Image Interpretation, Computer-Assisted --- Radionuclide Imaging --- Image Enhancement --- Tomography --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Diagnostic Imaging --- Photography --- Diagnostic Techniques, Radioisotope --- Diagnostic Techniques and Procedures --- Diagnosis --- Positron-Emission Tomography --- Tomography, Emission-Computed, Single-Photon --- Methods --- Medicine --- Health & Biological Sciences --- Radiology, MRI, Ultrasonography & Medical Physics --- Methodological Studies --- Methodological Study --- Procedures --- Studies, Methodological --- Study, Methodological --- Method --- Procedure --- Single-Photon Emission CT Scan --- Single-Photon Emission Computer-Assisted Tomography --- Single-Photon Emission Computerized Tomography --- CAT Scan, Single-Photon Emission --- CT Scan, Single-Photon Emission --- Radionuclide Tomography, Single-Photon Emission-Computed --- SPECT --- Single-Photon Emission-Computed Tomography --- Tomography, Single-Photon, Emission-Computed --- CAT Scan, Single Photon Emission --- CT Scan, Single Photon Emission --- Emission-Computed Tomography, Single-Photon --- Radionuclide Tomography, Single Photon Emission Computed --- Single Photon Emission CT Scan --- Single Photon Emission Computed Tomography --- Single Photon Emission Computer Assisted Tomography --- Single Photon Emission Computerized Tomography --- Tomography, Single-Photon Emission-Computed --- PET Imaging --- PET Scan --- Positron-Emission Tomography Imaging --- Tomography, Positron-Emission --- Imaging, PET --- Imaging, Positron-Emission Tomography --- PET Imagings --- PET Scans --- Positron Emission Tomography --- Positron Emission Tomography Imaging --- Positron-Emission Tomography Imagings --- Scan, PET --- Tomography Imaging, Positron-Emission --- Tomography, Positron Emission --- Antemortem Diagnosis --- Diagnoses and Examinations --- Examinations and Diagnoses --- Postmortem Diagnosis --- Diagnose --- Antemortem Diagnoses --- Diagnoses --- Diagnoses, Antemortem --- Diagnoses, Postmortem --- Diagnosis, Antemortem --- Diagnosis, Postmortem --- Postmortem Diagnoses --- Disease --- Diagnostic Technics and Procedures --- Technics and Procedures, Diagnostic --- Techniques and Procedures, Diagnostic --- Diagnostic Testing --- Testing, Diagnostic --- Sensitivity and Specificity --- Diagnostic Technic, Radioisotope --- Diagnostic Technics, Radioisotope --- Diagnostic Technique, Radioisotope --- Radioisotope Diagnostic Technic --- Radioisotope Diagnostic Technics --- Radioisotope Diagnostic Technique --- Radioisotope Diagnostic Techniques --- Technic, Radioisotope Diagnostic --- Technics, Radioisotope Diagnostic --- Technique, Radioisotope Diagnostic --- Techniques, Radioisotope Diagnostic --- Photographies --- Imaging, Diagnostic --- Imaging, Medical --- Medical Imaging --- Radiologic and Imaging Nursing --- Image Processing, Computer-Assisted --- Tomographies --- Anatomy, Cross-Sectional --- Image Quality Enhancement --- Enhancement, Image --- Enhancement, Image Quality --- Enhancements, Image --- Enhancements, Image Quality --- Image Enhancements --- Image Quality Enhancements --- Quality Enhancement, Image --- Quality Enhancements, Image --- Gamma Camera Imaging --- Radioisotope Scanning --- Scanning, Radioisotope --- Scintigraphy --- Scintiphotography --- Imaging, Gamma Camera --- Imaging, Radionuclide --- Image Interpretation, Computer Assisted --- Computer-Assisted Image Interpretation --- Computer-Assisted Image Interpretations --- Image Interpretations, Computer-Assisted --- Interpretation, Computer-Assisted Image --- Interpretations, Computer-Assisted Image --- Investigative Technics --- Investigative Technic --- Investigative Technique --- Technic, Investigative --- Technics, Investigative --- Technique, Investigative --- Techniques, Investigative --- Computed Tomographic Scintigraphy --- Emission-Computed Tomography --- Radionuclide Computer-Assisted Tomography --- Radionuclide Computerized Tomography --- Radionuclide-Computed Tomography --- Radionuclide-Emission Computed Tomography --- Tomography, Computerized Emission --- CAT Scan, Radionuclide --- CT Scan, Radionuclide --- Computerized Emission Tomography --- Radionuclide Tomography, Computed --- Scintigraphy, Computed Tomographic --- Tomography, Radionuclide-Computed --- CAT Scans, Radionuclide --- CT Scans, Radionuclide --- Computed Radionuclide Tomography --- Computed Tomography, Radionuclide-Emission --- Computer-Assisted Tomographies, Radionuclide --- Computer-Assisted Tomography, Radionuclide --- Computerized Tomography, Radionuclide --- Emission Computed Tomography --- Emission Tomography, Computerized --- Radionuclide CAT Scan --- Radionuclide CAT Scans --- Radionuclide CT Scan --- Radionuclide CT Scans --- Radionuclide Computed Tomography --- Radionuclide Computer Assisted Tomography --- Radionuclide Computer-Assisted Tomographies --- Radionuclide Emission Computed Tomography --- Scan, Radionuclide CAT --- Scan, Radionuclide CT --- Scans, Radionuclide CAT --- Scans, Radionuclide CT --- Tomographic Scintigraphy, Computed --- Tomographies, Radionuclide Computer-Assisted --- Tomography, Computed Radionuclide --- Tomography, Emission Computed --- Tomography, Radionuclide Computed --- Tomography, Radionuclide Computer-Assisted --- Tomography, Radionuclide Computerized --- Tomography, Radionuclide-Emission Computed --- diagnosis --- methods --- Tomography, Emission --- Methodology. --- Computerized emission tomography --- Emission tomography --- PET (Tomography) --- PET-CT (Tomography) --- Positron emission tomography --- Positron emission transaxial tomography --- Radionuclide tomography --- Scintigraphy, Tomographic --- Tomography, Radionuclide --- Diagnostic imaging --- Positrons --- Radioisotope scanning --- Data processing --- Emission