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Poxvirus --- Poxviruses --- Poxvirussen --- Poxviridae --- Poxvirus. --- Genetics --- Poxviruses. --- Genetics.
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Medical microbiology, virology, parasitology --- Poxviruses. --- Poxviridae.
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Recombinant vaccinia viruses have become important in recent years, both as protein expression vectors, and-in the age of bioterrorism-as powerful tools for developing new smallpox vaccines, diagnostics, and understanding of poxvirus pathogenesis. In Vaccinia Virus and Poxvirology: Methods and Protocols, internationally recognized experts and leaders in poxvirology describe in step-by-step detail the successful techniques they have perfected to study and work with vaccinia virus and other poxviruses. They offer cutting-edge techniques for the construction and characterization of recombinant viruses; for the study of poxvirus gene transcription and DNA replication; and for the use of the virus in immunologic and cell-cell fusion assays. Other methods cover poxvirus bioinformatics, aspects of viral pathogenesis at both a protein and an animal model level, and the study of immune responses to poxvirus-the latter critical to the important role of vaccinia virus in smallpox vaccination and its potential role as a vaccine vector directed against infectious agents and cancer. The protocols presented follow the successful Methods in Molecular Biology™ series format, each one offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and timely, Vaccinia Virus and Poxvirology: Methods and Protocols offers virologists and vaccinologists an unequaled source of proven techniques for understanding poxviruses and developing defenses against their use as bioterrorist agents.
Recombinant poxviruses --- Vaccinia --- Cowpox --- Vaccina --- Cattle --- Poxvirus diseases --- Genetically engineered poxviruses --- Poxviruses --- Recombinant viruses --- Virus diseases --- Genetic engineering --- Microbiology. --- Microbial biology --- Biology --- Microorganisms
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The recent international alarm at the possible use of smallpox as weapon of bioterror has refocused the attention of the scientific community, public health policy makers and the public on poxviruses. In contrast to the threat posed by some of these viruses, other poxviruses show exciting beneficial potential including their use as valuable tools in biomedical research and in the delivery of vaccines. This monograph provides a comprehensive review of the poxvirus family with a particular emphasis on current developments. It includes the latest insights into poxviral molecular biology, diagnosis, therapy, vaccine development and the beneficial exploitation of these viruses in biomedical research. Each chapter is written by a leader in the field. The reviews present all aspects of the field, including historical perspectives, along with summaries of the latest advances. This combination makes the book relevant for graduate students, researchers new to the field and to experienced poxvirologists.
Poxviruses. --- Poxvirus diseases. --- Virus diseases --- Poxviridae --- DNA viruses --- Microbiology. --- Medical Microbiology. --- Microbial biology --- Biology --- Microorganisms --- Medical microbiology.
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Orthopoxviruses Pathogenic for Humans covers those viruses capable of causing disease in man, including monkeypox, smallpox, cowpox, and vaccinia. The coverage of each virus is comprehensive, covering the biology, molecular biology, and ecology of the virus as well as the clinical and epidemiological aspects of these viruses in humans and animals. In addition, this volume highlights developments in genetic engineering that are paving the way for potential therapeutic treatments of these viruses.
Orthopoxviruses. --- Poxviruses. --- Poxviruses --- Poxviridae --- DNA viruses --- Medical virology. --- Immunology. --- Microbiology. --- Emerging infectious diseases. --- Epidemiology. --- Virology. --- Infectious Diseases. --- Public Health. --- Diseases --- Public health --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Microbial biology --- Biology --- Microorganisms --- Immunobiology --- Life sciences --- Serology --- Medical microbiology --- Virology --- Virus diseases --- Infectious diseases. --- Public health. --- Community health --- Health services --- Hygiene, Public --- Hygiene, Social --- Public health services --- Public hygiene --- Social hygiene --- Health --- Human services --- Biosecurity --- Health literacy --- Medicine, Preventive --- National health services --- Sanitation --- Microbiology
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Though smallpox was eradicated from the planet two decades ago, recent terrorist acts have raised the horrific possibility that rogue states, laboratories, or terrorist groups are in possession of secret stockpiles of the virus that causes the disease, and may be preparing to unleash it on target populations.
Cultures and culture media. --- Epidemiology. --- Health Policy. --- International cooperation. --- Prevention. --- prevention & control. --- Smallpox. --- Variola virus. --- Smallpox --- Orthopoxvirus --- Public Policy --- North America --- Internationality --- Europe, Eastern --- Poxviridae Infections --- Social Sciences --- DNA Virus Infections --- Social Control Policies --- Americas --- Chordopoxvirinae --- Europe --- Social Control, Formal --- Policy --- Poxviridae --- Virus Diseases --- Geographic Locations --- Anthropology, Education, Sociology and Social Phenomena --- Sociology --- DNA Viruses --- Health Care Economics and Organizations --- Diseases --- Geographicals --- Health Care --- Viruses --- Vertebrate Viruses --- Organisms --- International Cooperation --- Health Policy --- Variola virus --- Russia --- United States --- Public Health --- Health & Biological Sciences --- Communicable Diseases --- Healthcare Policy --- National Health Policy --- Health Policies --- Health Policy, National --- Healthcare Policies --- National Health Policies --- Policy, Health --- Policy, Healthcare --- Policy, National Health --- Policy Making --- Alastrim --- Variola --- Variola Minor --- Minor, Variola --- Minors, Variola --- Variola Minors --- Variolas --- Poxvirus variolae --- Smallpox Virus --- Smallpox Viruses --- Variola viruses --- Treaties --- Foreign Aid --- Aid, Foreign --- Cooperation, International --- Treaty --- Animal Viruses --- Zoophaginae --- Animal Virus --- Virus --- Virus, Animal --- Viruses, Animal --- Genetic Vectors --- Microbiology --- Community-Based Distribution --- Contraceptive Distribution --- Delivery of Healthcare --- Dental Care Delivery --- Distribution, Non-Clinical --- Distribution, Nonclinical --- Distributional Activities --- Healthcare --- Healthcare Delivery --- Healthcare Systems --- Non-Clinical Distribution --- Nonclinical Distribution --- Delivery of Dental Care --- Health Care Delivery --- Health Care Systems --- Activities, Distributional --- Activity, Distributional --- Care, Health --- Community Based Distribution --- Community-Based Distributions --- Contraceptive Distributions --- Deliveries, Healthcare --- Delivery, Dental Care --- Delivery, Health Care --- Delivery, Healthcare --- Distribution, Community-Based --- Distribution, Contraceptive --- Distribution, Non Clinical --- Distributional Activity --- Distributions, Community-Based --- Distributions, Contraceptive --- Distributions, Non-Clinical --- Distributions, Nonclinical --- Health Care System --- Healthcare Deliveries --- Healthcare System --- Non Clinical Distribution --- Non-Clinical Distributions --- Nonclinical Distributions --- System, Health Care --- System, Healthcare --- Systems, Health Care --- Systems, Healthcare --- Healthcare Economics and Organizations --- Health Care Economics --- Health Economics --- Healthcare Economics --- Care Economic, Health --- Economic, Health --- Economic, Health Care --- Economic, Healthcare --- Economics, Health Care --- Health Care Economic --- Health Economic --- Healthcare Economic --- DNA Virus --- Virus, DNA --- Viruses, DNA --- General Social Development and Population --- Viral Diseases --- Viral Infections --- Virus Infections --- Disease, Viral --- Disease, Virus --- Diseases, Viral --- Diseases, Virus --- Infection, Viral --- Infection, Virus --- Infections, Viral --- Infections, Virus --- Viral Disease --- Viral Infection --- Virus Disease --- Virus Infection --- Poxviruses --- Policies --- Regulation --- Social Control --- Control, Social --- Controls, Social --- Formal Social Control --- Formal Social Controls --- Regulations --- Social Controls --- Control Policies, Social --- Control Policy, Social --- Policies, Social Control --- Policy, Social Control --- Social Control Policy --- Infections, DNA Virus --- DNA Virus Infection --- Infection, DNA Virus --- Virus Infection, DNA --- Virus Infections, DNA --- Science, Social --- Sciences, Social --- Social Science --- Globalization --- International Aspects --- International Perspectives --- International Relations --- Multinational Aspects --- Multinational Perspectives --- Aspect, International --- Aspect, Multinational --- Aspects, International --- Aspects, Multinational --- International Aspect --- International Perspective --- Multinational Aspect --- Multinational Perspective --- Perspective, International --- Perspective, Multinational --- Perspectives, International --- Perspectives, Multinational --- Relations, International --- International Law --- Infections, Poxviridae --- Infections, Poxvirus --- Milker's Nodes --- Poxvirus Infections --- Infection, Poxviridae --- Infection, Poxvirus --- Milker Nodes --- Milker's Node --- Milkers Nodes --- Node, Milker's --- Nodes, Milker's --- Poxviridae Infection --- Poxvirus Infection --- Affirmative Action --- Migration Policy --- Population Policy --- Social Protection --- Social Policy --- Action, Affirmative --- Migration Policies --- Policies, Migration --- Policies, Population --- Policies, Public --- Policies, Social --- Policy, Migration --- Policy, Population --- Policy, Public --- Policy, Social --- Population Policies --- Protection, Social --- Public Policies --- Social Policies --- Camelpox virus --- Horsepox virus --- Raccoonpox virus --- Skunkpox virus --- Taterapox virus --- Volepox virus --- Camelpox viruses --- Horsepox viruses --- Orthopoxviruses --- Raccoonpox viruses --- Skunkpox viruses --- Taterapox viruses --- Volepox viruses --- virus, Camelpox --- virus, Horsepox --- virus, Raccoonpox --- virus, Skunkpox --- virus, Taterapox --- virus, Volepox --- Small pox --- Varioloid --- Poxvirus diseases --- Prevention --- Epidemiology --- Cultures and culture media --- Vertebrates --- virology --- Russian Federation (Europe) --- Russian SFSR --- Russian S.F.S.R. --- Geographic Location --- Northern Europe --- Southern Europe --- Western Europe --- America --- Eastern Europe --- Northern America --- Health Care Policies --- Care Policies, Health --- Health Care Policy --- Policies, Health --- Policies, Health Care --- Policies, Healthcare --- Policy, Health Care
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