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Drug resistance in microorganisms. --- Pathogenic microorganisms. --- Disease-causing microorganisms --- Micro-organisms, Pathogenic --- Pathogens --- Microorganisms --- Medical microbiology --- Virulence (Microbiology) --- Antibiotic resistance in microorganisms --- Antibiotics resistance in microorganisms --- Bacterial resistance to antibiotics --- Drug resistance in micro-organisms --- Microbial drug resistance --- Resistance to drugs in microorganisms --- Effect of drugs on --- Resistència als medicaments --- Microorganismes patògens
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Drug resistance in microorganisms. --- Antibiotic resistance in microorganisms --- Antibiotics resistance in microorganisms --- Bacterial resistance to antibiotics --- Drug resistance in micro-organisms --- Microbial drug resistance --- Resistance to drugs in microorganisms --- Microorganisms --- Effect of drugs on --- Resistència als medicaments. --- Malalties bacterianes grampositives --- Antibiòtics betalactàmics
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This book summarizes the emerging trends in the field of antibiotic resistance of various gram-negative and gram-positive bacterial species. The ability of different species of bacteria to resist the antimicrobial agent has become a global problem. As such, the book provides a comprehensive overview of the advances in our understanding of the origin and mechanism of resistance, discusses the modern concept of the biochemical and genetic basis of antibacterial resistance and highlights the clinical and economic implications of the increased prevalence of antimicrobial resistant pathogens and their ecotoxic effects. It also reviews various strategies to curtail the emergence and examines a number of innovative therapeutic approaches, such as CRISPR, phage therapy, nanoparticles and natural antimicrobials, to combat the spread of resistance.
Drug resistance. --- Infectious diseases. --- Bacteriology. --- Pharmaceutical technology. --- Drug Resistance. --- Infectious Diseases. --- Pharmaceutical Sciences/Technology. --- Pharmaceutical laboratory techniques --- Pharmaceutical laboratory technology --- Technology, Pharmaceutical --- Technology --- Microbiology --- Resistance to drugs --- Pharmacology --- Drug resistance in microorganisms. --- Antibiotic resistance in microorganisms --- Antibiotics resistance in microorganisms --- Bacterial resistance to antibiotics --- Drug resistance in micro-organisms --- Microbial drug resistance --- Resistance to drugs in microorganisms --- Microorganisms --- Effect of drugs on --- Resistència als medicaments --- Farmacoresistència --- Farmacologia --- Resistència a la insulina --- Efecte dels medicaments sobre els microorganismes
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Celebrating 100 years of HEP, this volume will discuss key pharmacological discoveries and concepts of the past 100 years. These discoveries have dramatically changed the medical treatment paradigms of many diseases and these concepts have and will continue to shape discovery of new medicinies. Newly evolving technologies will similarly be discussed as they will shape the future of the pharmacology and, accordingly, medical therapy.
Pharmacology, Experimental. --- Experimental pharmacology --- Therapeutics, Experimental --- Pharmacology. --- Pharmacology/Toxicology. --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemicals --- Chemotherapy --- Drugs --- Pharmacy --- Physiological effect --- Pharmacology --- Farmacologia --- Medicina --- Biofarmàcia --- Biotransformació (Metabolisme) --- Dermofarmacologia --- Desenvolupament de medicaments --- Estabilitat dels medicaments --- Farmacocinètica --- Farmacogenètica --- Farmacologia cardiovascular --- Farmacologia clínica --- Farmacologia dental --- Farmacologia geriàtrica --- Farmacologia molecular --- Farmacologia obstètrica --- Farmacologia ocular --- Farmacologia pediàtrica --- Farmacologia respiratòria --- Farmacologia renal --- Farmacologia veterinària --- Immunofarmacologia --- Isòtops radioactius en farmacologia --- Neurofarmacologia --- Psicofarmacologia --- Química farmacèutica --- Radiofàrmacs --- Resistència als medicaments --- Toxicologia --- Medicaments --- Quimioteràpia --- Fotofarmacologia
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This volume covers several aspects of rational drug design, such as synthesis of novel bioactive drugs; development and application of new methodologies; computational methods valuable for the establishment of new approaches in drug discovery; and the effects of physical-chemical and ADMET properties of the designed potential drugs. Chapters guide readers through amyloid deposits, Saturation Transfer Difference (STD) NMR, methods on bioguided design, the importance of lipophilicity in drug design, ADMET, FRET, structural biology, and homology modeling. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Rational Drug Design: Methods and Protocols aims to ensure successful results in the further study of this vital field.
Toxicology. --- Pharmacology/Toxicology. --- Chemicals --- Medicine --- Pharmacology --- Poisoning --- Poisons --- Toxicology --- Disseny de medicaments --- Farmacologia --- Manuals de laboratori --- Tècniques de laboratori --- Medicina --- Biofarmàcia --- Biotransformació (Metabolisme) --- Dermofarmacologia --- Desenvolupament de medicaments --- Estabilitat dels medicaments --- Farmacocinètica --- Farmacogenètica --- Farmacologia cardiovascular --- Farmacologia clínica --- Farmacologia dental --- Farmacologia geriàtrica --- Farmacologia molecular --- Farmacologia obstètrica --- Farmacologia ocular --- Farmacologia pediàtrica --- Farmacologia respiratòria --- Farmacologia renal --- Farmacologia veterinària --- Immunofarmacologia --- Isòtops radioactius en farmacologia --- Neurofarmacologia --- Psicofarmacologia --- Química farmacèutica --- Radiofàrmacs --- Resistència als medicaments --- Toxicologia --- Medicaments --- Quimioteràpia --- Disseny de fàrmacs --- Disseny farmacèutic --- Fotofarmacologia
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Antiviral agents --- Development. --- Antiviral drugs --- Antivirals --- Anti-infective agents --- Virus diseases --- Virus inhibitors --- Chemotherapy --- Antiretrovirals --- Farmacologia --- Medicina --- Biofarmàcia --- Biotransformació (Metabolisme) --- Dermofarmacologia --- Desenvolupament de medicaments --- Estabilitat dels medicaments --- Farmacocinètica --- Farmacogenètica --- Farmacologia cardiovascular --- Farmacologia clínica --- Farmacologia dental --- Farmacologia geriàtrica --- Farmacologia molecular --- Farmacologia obstètrica --- Farmacologia ocular --- Farmacologia pediàtrica --- Farmacologia respiratòria --- Farmacologia renal --- Farmacologia veterinària --- Fotofarmacologia --- Immunofarmacologia --- Isòtops radioactius en farmacologia --- Neurofarmacologia --- Psicofarmacologia --- Química farmacèutica --- Radiofàrmacs --- Resistència als medicaments --- Toxicologia --- Medicaments --- Quimioteràpia --- Agents antiretrovirals --- Fàrmacs antiretrovirals --- Medicaments antiretrovirals --- Medicaments antivírics
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Drug resistance in cancer cells. --- Multiple myeloma --- Treatment. --- Kahler's disease --- Plasma cell myeloma --- B cells --- Monoclonal gammopathies --- Plasmacytoma --- Antitumor drug resistance --- Cancer drug resistance --- Drug resistance in cancer --- Drug resistance in tumor cells --- Cancer cells --- Tumors --- Mieloma múltiple --- Resistència als medicaments --- Farmacoresistència --- Farmacologia --- Resistència a la insulina --- Efecte dels medicaments sobre els microorganismes --- Malaltia de Bozzolo --- Malaltia de Kahler --- Mieloma de cèl·lules plasmàtiques --- Mielomatosi --- Osteomieloma
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Pharmacy. --- Bioinformatics. --- Bio-informatics --- Biological informatics --- Biology --- Information science --- Computational biology --- Systems biology --- Chemistry --- Medicine --- Drugs --- Materia medica --- Pharmacology --- Data processing --- Farmacologia --- Bioinformàtica --- Informàtica biològica --- Ciències de la informació --- Biologia computacional --- Medicina --- Biofarmàcia --- Biotransformació (Metabolisme) --- Dermofarmacologia --- Desenvolupament de medicaments --- Estabilitat dels medicaments --- Farmacocinètica --- Farmacogenètica --- Farmacologia cardiovascular --- Farmacologia clínica --- Farmacologia dental --- Farmacologia geriàtrica --- Farmacologia molecular --- Farmacologia obstètrica --- Farmacologia ocular --- Farmacologia pediàtrica --- Farmacologia respiratòria --- Farmacologia renal --- Farmacologia veterinària --- Fotofarmacologia --- Immunofarmacologia --- Isòtops radioactius en farmacologia --- Neurofarmacologia --- Psicofarmacologia --- Química farmacèutica --- Radiofàrmacs --- Resistència als medicaments --- Toxicologia --- Medicaments --- Quimioteràpia
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Potassium channels. --- Channels, Potassium --- Ion channels --- Canals de potassi --- Farmacologia --- Medicina --- Biofarmàcia --- Biotransformació (Metabolisme) --- Dermofarmacologia --- Desenvolupament de medicaments --- Estabilitat dels medicaments --- Farmacocinètica --- Farmacogenètica --- Farmacologia cardiovascular --- Farmacologia clínica --- Farmacologia dental --- Farmacologia geriàtrica --- Farmacologia molecular --- Farmacologia obstètrica --- Farmacologia ocular --- Farmacologia pediàtrica --- Farmacologia respiratòria --- Farmacologia renal --- Farmacologia veterinària --- Fotofarmacologia --- Immunofarmacologia --- Isòtops radioactius en farmacologia --- Neurofarmacologia --- Psicofarmacologia --- Química farmacèutica --- Radiofàrmacs --- Resistència als medicaments --- Toxicologia --- Medicaments --- Quimioteràpia --- Canals potàssics --- Canals iònics
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Farmacologia --- Medicina --- Biofarmàcia --- Biotransformació (Metabolisme) --- Dermofarmacologia --- Desenvolupament de medicaments --- Estabilitat dels medicaments --- Farmacocinètica --- Farmacogenètica --- Farmacologia cardiovascular --- Farmacologia clínica --- Farmacologia dental --- Farmacologia geriàtrica --- Farmacologia molecular --- Farmacologia obstètrica --- Farmacologia ocular --- Farmacologia pediàtrica --- Farmacologia respiratòria --- Farmacologia renal --- Farmacologia veterinària --- Immunofarmacologia --- Isòtops radioactius en farmacologia --- Neurofarmacologia --- Psicofarmacologia --- Química farmacèutica --- Radiofàrmacs --- Resistència als medicaments --- Toxicologia --- Medicaments --- Quimioteràpia --- Wnt proteins. --- Neuropharmacology. --- Pharmacology. --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemicals --- Chemotherapy --- Drugs --- Pharmacy --- Nervous system --- Neurotropic drugs --- Neurosciences --- Pharmacology --- Glycoproteins --- Growth factors --- Physiological effect --- Effect of drugs on --- Fotofarmacologia
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