Narrow your search
Listing 1 - 10 of 13 << page
of 2
>>
Sort by

Book
Quelles sont les stratégies actuelles pour lutter contre les biofilms à S. epidermidis ?
Authors: --- ---
Year: 2018 Publisher: Bruxelles: UCL. Faculté de pharmacie et des sciences biomédicales,

Loading...
Export citation

Choose an application

Bookmark

Abstract

S. Epidermidis is commensal bacteria of the skin and mucous membranes. Biofilms refer to communities of microorganism that adhere to a support.The use of biomaterials can lead to infections and in some cases, lead to sepsis.The matrix produced by the bacteria confers protection against the action of immune system and antibiotic therapy. Several researchers are trying to put in place strategies against S. Epidermidis biofilms. These approaches are available in preventive and curative strategies. In prevention, the development of a vaccine or the use of chelating agents are proposed to target the biofilm. However, when the patients is infected, the researchers will target the components of the matrix. Techniques proposed are the use of bacteriophages and the inhibition of quorum sensing. Other teams have studied the interest of dispersing the biofilm and thus male the isolated bacteria again sensitive to the antibiotic. The use of enzymes, ultrasound using microbubbles and nanoparticles are techniques used in the dispersion of the matrix. A better understanding of host-pathogen relationships and elucidation of biofilm biology would reveal new targets for combating infections with S epidermidis biofilms. S. Epidermidis est une bactérie commensale de la peau et des muqueuses. Les biofilms désignent des communautés de microorganismes qui adhérent sur un support. L’usage de biomatériaux peut entraîner des infections et, dans certains cas, mener à des septicémies. La matrice produite par les bactéries confère une protection contre l’action du système immunitaire et l’antibiothérapie. Plusieurs équipes tentent de mettre en place des stratégies préventives et curatives. Actuellement, les alternatives thérapeutiques consistent au retrait du matériel et/ou à une antibiothérapie. Vu l’émergence de souches résistantes et l’impact clinique associées aux biofilms, de nombreuses pistes expérimentales sont développées. En prévention, le développement d’un vaccin ou l’usage d’agents chélateurs sont proposés pour cibler le biofilm. Cependant, quand le patient est infecté, les chercheurs vont cibler les composants de la matrice. Les techniques proposées sont l’usage de bactériophages et l’inhibition du quorum sensing. D’autres équipes ont étudié l’intérêt de disperser le biofilm et ainsi rendre les bactéries isolées à nouveau sensibles à l’antibiotique. L’emploi d’enzymes, les ultrasons à l’aide de microbulles et les nanoparticules sont les techniques utilisées dans la dispersion de la matrice. Une meilleure compréhension des relations hôte-pathogène et l’élucidation de la biologie du biofilm permettraient de dévoiler de nouvelles cibles pour combattre les infections des biofilms à S. epidermidis.


Dissertation
Evaluation d'un schéma posologique de la gentamicine au moyen d'un dosage microbiologique
Author:
Year: 1977 Publisher: Liège : Université de Liège. Faculté de médecine (ULg). Département de clinique et pathologie médicales,

Loading...
Export citation

Choose an application

Bookmark

Abstract


Dissertation
Coagulase-negative staphylococci in the hospital environment with emphasis on staphylococcus epidermidis
Authors: ---
ISBN: 9073118077 Year: 2002 Publisher: Leiden Universiteit Leiden

Loading...
Export citation

Choose an application

Bookmark

Abstract


Book
Recent Progress in Antimicrobial Nanomaterials
Author:
Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

Loading...
Export citation

Choose an application

Bookmark

Abstract

Based on a fundamental understanding of the interaction between bacteria and nanomaterials, this book highlights the latest research on the antimicrobial properties of nanomaterials and provides an invaluable blueprint for improving the antimicrobial performance of devices and products. This book introduces the reader to the progress being made in the field, followed by an outline of applications in different areas. Various methods and techniques of synthesis and characterization are detailed. The content provides insight into the ongoing research, current trends, and technical challenges in this rapidly progressing field. Therefore, this book is highly suitable for materials scientists, engineers, biologists, and technologists.


Book
Recent Progress in Antimicrobial Nanomaterials
Author:
Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

Loading...
Export citation

Choose an application

Bookmark

Abstract

Based on a fundamental understanding of the interaction between bacteria and nanomaterials, this book highlights the latest research on the antimicrobial properties of nanomaterials and provides an invaluable blueprint for improving the antimicrobial performance of devices and products. This book introduces the reader to the progress being made in the field, followed by an outline of applications in different areas. Various methods and techniques of synthesis and characterization are detailed. The content provides insight into the ongoing research, current trends, and technical challenges in this rapidly progressing field. Therefore, this book is highly suitable for materials scientists, engineers, biologists, and technologists.


Book
Recent Progress in Antimicrobial Nanomaterials
Author:
Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

Loading...
Export citation

Choose an application

Bookmark

Abstract

Based on a fundamental understanding of the interaction between bacteria and nanomaterials, this book highlights the latest research on the antimicrobial properties of nanomaterials and provides an invaluable blueprint for improving the antimicrobial performance of devices and products. This book introduces the reader to the progress being made in the field, followed by an outline of applications in different areas. Various methods and techniques of synthesis and characterization are detailed. The content provides insight into the ongoing research, current trends, and technical challenges in this rapidly progressing field. Therefore, this book is highly suitable for materials scientists, engineers, biologists, and technologists.


Book
Staphylococcal Infections (Host and Pathogenic Factors)
Author:
Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

Loading...
Export citation

Choose an application

Bookmark

Abstract

Although 30% of the healthy human population is colonized with various Staphylococcus species, some staphylococcal strains, referred to as opportunistic pathogens, can cause minor to life-threatening diseases. The pathogenicity of these bacteria depends on their virulence factors and the robustness of the regulatory networks expressing these virulence factors. Virulence factors of pathogenic Staphylococcus spp. consist of numerous toxins, enterotoxins (some of which act as superantigens), enzymes, and proteins (cytoplasmic, extracellular, and surface) that are regulated by two-component (TC) and quorum-sensing (QS) regulatory networks. To enter this niche, some other Staphylococcus species, such as Staphylococcus simulans, produce a potent endopeptidase called lysostaphin, which can inhibit the growth of pathogenic S. aureus. Some other Staphylococcus species produce autolysins and cationic peptides to win the intra- and inter-species competition. The outcome of this microbial invasion depends not only on pathogenic factors but also on the host’s internal and external defense mechanisms, including a healthy skin microbiome. A healthy skin microbiome population can prevent colonization by other major pathogens. As normal host microflora, these commensals establish a complex relationship with the host as well as the surrounding microbial communities. This Special Issue of Microorganisms is focused on studies and recent advancements in our understanding of staphylococcal virulence mechanisms that enable Staphylococcus spp. either to successfully establish themselves as a colonizer or to overcome the host’s defense system to cause infection along with our effort to make an anti-staphylococcal vaccine.

Keywords

Research & information: general --- Biology, life sciences --- biofilm --- MRSA --- silver ion --- silver sulfadiazine --- wound infections --- Staphylococcus aureus --- methicillin resistance --- human infection --- CC130 --- biomaterials --- medical devices --- HL-60 cells --- PMNs --- endotracheal tube --- titanium --- implantable devices --- nosocomial diseases --- Staphylococcus lugdunensis --- sortase A --- surface proteins --- LPXTG --- small colony variants --- influenza virus --- super-infection --- pro-inflammatory response --- rural Ghana --- molecular epidemiology --- chronic wounds --- invasive disease --- surgery-associated infection --- sepsis --- SA4Ag vaccine --- conjugated polysaccharide --- ClfA --- MntC --- protection --- animal models --- phase variation --- Staphylococcus epidermidis --- microbiota --- multidrug resistance --- genome sequencing --- phylogenetic analyses --- arthroplasty surgery --- methicillin-resistant Staphylococcus aureus (MRSA) --- community-associated MRSA (CA-MRSA) --- CA-MRSA strain USA300 --- murine skin infection model --- dermatopathology --- dermonecrosis --- neutrophil --- host antibacterial response --- cytokine --- chemokine --- physiology --- metabolism --- carbon catabolite repression --- CcpA --- HPr --- colonization --- mouse --- JSNZ --- aurintricarboxylic acid --- ATA --- adhesion inhibitor --- mupirocin --- nose --- superantigen --- mastitis --- food intoxication --- regulation --- sec variants --- CM lipids --- daptomycin resistance --- resensitization --- n/a


Book
Staphylococcal Infections (Host and Pathogenic Factors)
Author:
Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

Loading...
Export citation

Choose an application

Bookmark

Abstract

Although 30% of the healthy human population is colonized with various Staphylococcus species, some staphylococcal strains, referred to as opportunistic pathogens, can cause minor to life-threatening diseases. The pathogenicity of these bacteria depends on their virulence factors and the robustness of the regulatory networks expressing these virulence factors. Virulence factors of pathogenic Staphylococcus spp. consist of numerous toxins, enterotoxins (some of which act as superantigens), enzymes, and proteins (cytoplasmic, extracellular, and surface) that are regulated by two-component (TC) and quorum-sensing (QS) regulatory networks. To enter this niche, some other Staphylococcus species, such as Staphylococcus simulans, produce a potent endopeptidase called lysostaphin, which can inhibit the growth of pathogenic S. aureus. Some other Staphylococcus species produce autolysins and cationic peptides to win the intra- and inter-species competition. The outcome of this microbial invasion depends not only on pathogenic factors but also on the host’s internal and external defense mechanisms, including a healthy skin microbiome. A healthy skin microbiome population can prevent colonization by other major pathogens. As normal host microflora, these commensals establish a complex relationship with the host as well as the surrounding microbial communities. This Special Issue of Microorganisms is focused on studies and recent advancements in our understanding of staphylococcal virulence mechanisms that enable Staphylococcus spp. either to successfully establish themselves as a colonizer or to overcome the host’s defense system to cause infection along with our effort to make an anti-staphylococcal vaccine.

Keywords

Research & information: general --- Biology, life sciences --- biofilm --- MRSA --- silver ion --- silver sulfadiazine --- wound infections --- Staphylococcus aureus --- methicillin resistance --- human infection --- CC130 --- biomaterials --- medical devices --- HL-60 cells --- PMNs --- endotracheal tube --- titanium --- implantable devices --- nosocomial diseases --- Staphylococcus lugdunensis --- sortase A --- surface proteins --- LPXTG --- small colony variants --- influenza virus --- super-infection --- pro-inflammatory response --- rural Ghana --- molecular epidemiology --- chronic wounds --- invasive disease --- surgery-associated infection --- sepsis --- SA4Ag vaccine --- conjugated polysaccharide --- ClfA --- MntC --- protection --- animal models --- phase variation --- Staphylococcus epidermidis --- microbiota --- multidrug resistance --- genome sequencing --- phylogenetic analyses --- arthroplasty surgery --- methicillin-resistant Staphylococcus aureus (MRSA) --- community-associated MRSA (CA-MRSA) --- CA-MRSA strain USA300 --- murine skin infection model --- dermatopathology --- dermonecrosis --- neutrophil --- host antibacterial response --- cytokine --- chemokine --- physiology --- metabolism --- carbon catabolite repression --- CcpA --- HPr --- colonization --- mouse --- JSNZ --- aurintricarboxylic acid --- ATA --- adhesion inhibitor --- mupirocin --- nose --- superantigen --- mastitis --- food intoxication --- regulation --- sec variants --- CM lipids --- daptomycin resistance --- resensitization --- n/a


Book
Staphylococcal Infections (Host and Pathogenic Factors)
Author:
Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

Loading...
Export citation

Choose an application

Bookmark

Abstract

Although 30% of the healthy human population is colonized with various Staphylococcus species, some staphylococcal strains, referred to as opportunistic pathogens, can cause minor to life-threatening diseases. The pathogenicity of these bacteria depends on their virulence factors and the robustness of the regulatory networks expressing these virulence factors. Virulence factors of pathogenic Staphylococcus spp. consist of numerous toxins, enterotoxins (some of which act as superantigens), enzymes, and proteins (cytoplasmic, extracellular, and surface) that are regulated by two-component (TC) and quorum-sensing (QS) regulatory networks. To enter this niche, some other Staphylococcus species, such as Staphylococcus simulans, produce a potent endopeptidase called lysostaphin, which can inhibit the growth of pathogenic S. aureus. Some other Staphylococcus species produce autolysins and cationic peptides to win the intra- and inter-species competition. The outcome of this microbial invasion depends not only on pathogenic factors but also on the host’s internal and external defense mechanisms, including a healthy skin microbiome. A healthy skin microbiome population can prevent colonization by other major pathogens. As normal host microflora, these commensals establish a complex relationship with the host as well as the surrounding microbial communities. This Special Issue of Microorganisms is focused on studies and recent advancements in our understanding of staphylococcal virulence mechanisms that enable Staphylococcus spp. either to successfully establish themselves as a colonizer or to overcome the host’s defense system to cause infection along with our effort to make an anti-staphylococcal vaccine.


Book
Marine Chitin 2019
Authors: ---
ISBN: 3039360736 3039360728 Year: 2020 Publisher: MDPI - Multidisciplinary Digital Publishing Institute

Loading...
Export citation

Choose an application

Bookmark

Abstract

In 2019, we sent out a call for submissions to a Special Issue of Marine Drugs entitled “Marine Chitin 2019”, and we are pleased that this issue has now been published. Over 16 high-impact papers were included in this issue, which we now plan to publish as a book. In addition, we now seek to publish a further Special Issue of Marine Drugs, “Marine Chitin 2020–2021”. As before, we plan to produce an authoritative and exciting issue that will encompass breakthroughs in scientific and industrial chitin and chitosan research. Significant advances in chitin and chitosan research have been made since the 1970s, and current overviews in recent publications involving chitin and chitosan research advances are in need of an update.

Keywords

chitosan hydrogel --- chitosan --- biotechnology --- RAW264.7 macrophage --- ?-glucosidase inhibitor --- bromotyrosines --- layer-by-layer film --- amphiphilic polymer --- conjugation --- marine resources --- antioxidant activity --- chitooligosaccharides --- methylene blue --- nanoparticles --- bulk density --- Eudragit® S100 --- lytic polysaccharide monooxygenase --- chitosan oleate salt --- curcumin --- RAW 264.7 cells --- antioxidant --- crude oil --- ball milling --- anti-inflammatory action --- enzymatic modification --- dissolution --- vaginal infections --- Hausner ratio --- crushing strength --- Staphylococcus epidermidis --- mucoadhesive film --- Caco-2 cell culture --- chitosan lactate --- 2D correlation spectroscopy --- chitosan citrate --- direct compression --- chitosan oligomers --- chitin deacetylase --- Pseudomonas aeruginosa --- collagen --- blood --- express method --- sodium carbonate --- HIV sexual transmission --- streptomycin --- antibacterial activity --- pork sausage --- nanocomposites --- chitosanase --- Clostridium perfringens --- chitinase --- mucoadhesion --- chitosan oligosaccharides --- chitosan tartrate --- Staphylococcus aureus --- immunostimulatory activity --- derivatization --- pH responsive release --- soluble chitosan complex --- chitin --- polymer film --- compression work --- wound treatment --- biofilms --- roller compaction --- mitogen-activated protein kinases (MAPK) --- Paenibacillus --- chitooligosaccharide --- mechanical property --- protease --- Polybius henslowii --- scaffolds --- electrospinning --- chitosan-coated liposomes --- phosphoinositide 3-kinases (PI3K)/Akt --- cytotoxicity --- polymorph --- vaginal preexposure prophylaxis --- Aplysina archeri --- antifungal activity --- PLGA --- Kawakita analysis --- marine sponges --- Tenofovir controlled release --- nile red

Listing 1 - 10 of 13 << page
of 2
>>
Sort by