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Sequential analysis --- 519.244 --- Mathematical statistics --- Statistical decision --- 519.244 Sequential methods. Optimal stopping. Cusum technique (cumulative sum technique) --- Sequential methods. Optimal stopping. Cusum technique (cumulative sum technique)

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519.244 --- 519.2 --- 519.2 Probability. Mathematical statistics --- Probability. Mathematical statistics --- 519.244 Sequential methods. Optimal stopping. Cusum technique (cumulative sum technique) --- Sequential methods. Optimal stopping. Cusum technique (cumulative sum technique) --- Mathematical statistics

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This book describes group sequential stopping rules designed to reduce average study length and control Type I and Type II error probabilities. The authors present one-sided and two-sided tests, introduce several families of group sequential tests, and explain how to choose the most appropriate test and interim analysis schedule. Their topics include placebo-controlled randomized trials, bio-equivalence testing, crossover and longitudinal studies, and linear and generalized linear models. Group Sequential Methods with Applications to Clinical Trials effectively surveys and extends modern methods for planning and conducting interim analyses.

Mathematical statistics --- Clinical trials --- Decision Theory --- Statistics as Topic --- Clinical Trials as Topic --- Models, Statistical --- Etudes cliniques --- Statistical methods. --- methods --- Méthodes statistiques --- 519.244 --- -Controlled clinical trials --- Patient trials of new treatments --- Randomized clinical trials --- Trials, Clinical --- Clinical medicine --- Human experimentation in medicine --- Sequential methods. Optimal stopping. Cusum technique (cumulative sum technique) --- Statistical methods --- Research --- Decision Theory. --- Statistics --- Clinical Trials --- Models, Statistical. --- methods. --- -Sequential methods. Optimal stopping. Cusum technique (cumulative sum technique) --- 519.244 Sequential methods. Optimal stopping. Cusum technique (cumulative sum technique) --- -519.244 Sequential methods. Optimal stopping. Cusum technique (cumulative sum technique) --- Controlled clinical trials --- Clinical trials - Statistical methods. --- Statistics as Topic - methods --- Clinical Trials as Topic - methods --- Etudes cliniques - Méthodes statistiques

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Mathematical statistics --- Quality control --- Statistique mathématique --- Qualité --- Contrôle --- 519.244 --- Mathematics --- Statistical inference --- Statistics, Mathematical --- Statistics --- Probabilities --- Sampling (Statistics) --- Factory management --- Industrial engineering --- Reliability (Engineering) --- Standardization --- Quality assurance --- Quality of products --- Sequential methods. Optimal stopping. Cusum technique (cumulative sum technique) --- Statistical methods --- Mathematical statistics. --- Quality control. --- 519.244 Sequential methods. Optimal stopping. Cusum technique (cumulative sum technique) --- Statistique mathématique --- Qualité --- Contrôle --- Statistique mathematique --- Controle de qualite

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Confidence intervals --- Sequential analysis --- Statistical hypothesis testing --- Intervalles de confiance --- Dualité, théorie de la (Mathématiques) --- Tests d'hypothèses (Statistique) --- 519.244 --- Hypothesis testing (Statistics) --- Significance testing (Statistics) --- Statistical significance testing --- Testing statistical hypotheses --- Distribution (Probability theory) --- Hypothesis --- Mathematical statistics --- Statistical decision --- Confidence limits --- Confidence regions --- Intervals, Confidence --- Limits, Confidence --- Regions, Confidence --- Sampling (Statistics) --- Statistical tolerance regions --- Sequential methods. Optimal stopping. Cusum technique (cumulative sum technique) --- Confidence intervals. --- Sequential analysis. --- Statistical hypothesis testing. --- 519.244 Sequential methods. Optimal stopping. Cusum technique (cumulative sum technique) --- Dualité, théorie de la (Mathématiques) --- Tests d'hypothèses (Statistique)