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Social interaction. --- Social interaction

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"As Ragnar Rommetveit put it forty years ago, dialogue is "the architecture of intersubjectivity": a tool for not only mantaining yet also constantly transforming our life-worlds. The volume advances and empirically illustrates the role of talk-in-interaction in displaying, ratifying, creating yet also defying the crucial dimensions of the world we live in. This process is particularly noticeable in children's primary social worlds, i.e. home and school where they are socialized to becoming competent members of the communities they (will) live in. Drawing on fifty years of research on children socialization through language and social interaction, the volume provides new multidisciplinary insights and updated empirical data on the process through which cultures, identities, and knowledge are brought into being through the everyday dialogues that animate children's life at home and school. The volume addresses a specialized readership, its interdisciplinary framework ensures that it will be of great interest to scholars from different academic fields, e.g. social and developmental psychology, anthropology, education, developmental linguistics, sociolinguistics and developmental pragmatics"--

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In 1900, Paul Ehrlich, who was studying ricin and abrin at the time, discovered antibodies and paved the way for immunotherapy. After 120 years, Ehrlich's insight into the therapeutic potential of immunotargeting is still a source of inspiration for many scientists. One of the most studied antibody-based targeting strategies is the carrying of powerful toxins. The generated molecules are immunotoxins, i.e., chimeric proteins obtained by coupling bacterial or plant toxins and antibodies through chemical linking or genetic engineering. Immunotoxins are functionally designed to eliminate the cells responsible for pathological conditions, and they find applications in several fields, ranging from cancer to immunological diseases or pain control. Despite the lack of specificity, even native toxins find clinical application, but the use of unconjugated toxins is limited to loco-regional treatments. A fundamental requirement for the medical application of toxins and their immunoconjugates is in-depth knowledge of their interaction with target cells in terms of binding, uptake, intracellular routing, and substrate specificity. This Special Issue focuses on toxins and immunotoxins that have clinical potential. We hope to give the reader a comprehensive overview of new toxin delivery strategies and toxin-based experimental disease models, both in vitro and in vivo.

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Growing evidence supports the important role of nutrition in health and performance. Nutritional interventions, alone or in combination with physical exercise, have proven effective for reducing the incidence of different chronic diseases and their associated risk factors (e.g., obesity, diabetes, hypertension, hypercholesterolemia). A healthy diet also seems to prevent many of the detrimental consequences of aging, notably sarcopenia and frailty. On the other hand, diet has been reported to influence physical performance, with nutrition, including nutritional supplements, being a cornerstone in the armamentarium of athletes. The role of nutrition seems, therefore, wide; however, although research is rapidly growing, controversy and debate still exists as to the optimal nutritional strategies for disease prevention and sports performance enhancement. The present Special Issue aimed to report recent findings on the role of nutrition in disease prevention and sports performance enhancement, as well as to summarize current evidence on these topics.

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