Listing 1 - 10 of 17 | << page >> |
Sort by
|
Choose an application
Choose an application
Insulin-like grow factor-binding proteins --- Somatomedin --- Somatomedin --- Pathophysiology --- Physiological effect
Choose an application
Pathological endocrinology --- Paediatrics --- Growth disorders. --- Somatomedin. --- Somatostatin. --- Somatotropin. --- Growth Disorders.
Choose an application
Insulin-like growth factor-binding proteins --- Somatomedins --- Congresses. --- congresses. --- Protein binding --- Congresses --- Somatomedin
Choose an application
Somatomedin --- Congresses --- Insulin-like growth factor-binding proteins --- Insulin --- Receptors, endogenous substances --- Receptors, insulin --- Somatomedins
Choose an application
Somatotropin --- Somatomedin --- Somatostatin --- Growth Hormone-Releasing Hormone --- Growth Hormone --- Growth Disorders
Choose an application
Animal embryology and growth --- Pathological endocrinology --- Human physiology --- Somatomedin --- Mammals --- Congresses --- Growth --- Somatomedins --- Growth and Development --- Development and Growth --- Developmental Biology --- Insulin Like Growth Factors --- Insulin-Like Growth Factors --- Sulfation Factor --- Factor, Sulfation --- Factors, Insulin-Like Growth --- Growth Factors, Insulin-Like --- Insulin-Like Growth Factor --- Factor, Insulin-Like Growth --- Growth Factor, Insulin-Like --- Insulin Like Growth Factor --- Somatomedin - Congresses --- Mammals - Growth - Congresses
Choose an application
Somatomedin --- Mechanism of action --- Congresses --- Insulin-like growth factor-binding proteins --- Insulin --- Somatomedin - Mechanism of action - Congresses. --- Insulin-like growth factor-binding proteins - Congresses. --- Insulin - Mechanism of action - Congresses. --- CENTRAL NERVOUS SYSTEM --- INSULIN --- INSULIN-LIKE GROWTH FACTOR I --- INSULIN-LIKE GROWTH FACTOR II --- RECEPTORS, INSULIN --- PHYSIOLOGY --- CONGRESSES --- CONGRESS
Choose an application
Insulin-like growth factors (IGFs), their binding proteins and their receptors play important roles in regulating growth, metabolism, proliferation and survival for many cells and tissues throughout lifespan in humans and other species. Circulating IGF1 is known to be an endocrine regulator, with metabolic effects related to, and partly convergent with, insulin signalling. IGF1 also mediates many of the growth promoting effects of GH, and there is an ongoing debate as to the relative contributions of endocrine-, vs locally-derived IGF1 for systemic growth. More recently however, it has become clear that IGFs may be key local growth and cellular survival factors for many different tissues, active from early in embryonic development, essential for normal maturation and growth during foetal life. IGFs continue to play important roles throughout adult life in many diverse processes such as tissue repair, cellular proliferation, tissue remodelling and metabolic regulation. IGF systems are tightly regulated; orderly control of cellular repair and metabolism is central to healthy ageing, whilst uncontrolled proliferation can lead to cancer.
Insulin-like growth factor-binding proteins. --- Somatomedin. --- Somatomedin --- Insulin-like growth factor-binding proteins --- Blood Proteins --- Intercellular Signaling Peptides and Proteins --- Carrier Proteins --- Publication Formats --- Somatomedins --- Insulin-Like Growth Factor Binding Proteins --- Congresses --- Publication Characteristics --- Biological Factors --- Peptides --- Proteins --- Chemicals and Drugs --- Amino Acids, Peptides, and Proteins --- Human Anatomy & Physiology --- Medicine --- Animal Biochemistry --- Neuroscience --- Clinical Endocrinology --- Health & Biological Sciences --- IGF-binding proteins --- Somatomedin-binding proteins --- Insulin-like growth factor --- Nonsuppressible insulinlike activity --- Sulfation factor --- Sulphation factor --- Thymidine factor --- Medicine. --- Medical genetics. --- Human physiology. --- Endocrinology. --- Medicine & Public Health. --- Human Physiology. --- Gene Function. --- Carrier proteins --- Growth factors --- Somatotropin
Choose an application
The insulin-like growth factor system has been shown to play a critical role in cancer development and progression. Insulin-like Growth Factors and Cancer: From Basic Biology to Therapeutics, specifically brings these aspects to the reader. The volume covers the epidemiological aspects of the relationships between circulating insulin and IGF-1 levels and the risk for cancer and cancer-related mortality and in particularly in disease states such as obesity and Type 2 diabetes. It then addresses the basic biology of the system and how the ligands, receptors and IGF-binding proteins affect cancer cell biology and cancer progression. Finally, it discusses the therapeutic potential of inhibiting the receptors using various newly discovered monoclonal antibodies and tyrosine kinase inhibitors that are in preclinical and clinical trials.
Cancer -- Endocrine aspects. --- Somatomedin. --- Tumors -- Growth. --- Somatomedin --- Insulin-like growth factor-binding proteins --- Cancer --- Tumors --- Intercellular Signaling Peptides and Proteins --- Carrier Proteins --- Blood Proteins --- Diseases --- Biological Factors --- Proteins --- Peptides --- Chemicals and Drugs --- Amino Acids, Peptides, and Proteins --- Somatomedins --- Neoplasms --- Insulin-Like Growth Factor Binding Proteins --- Medicine --- Human Anatomy & Physiology --- Health & Biological Sciences --- Oncology --- Animal Biochemistry --- Endocrine aspects --- Growth --- Insulin-like growth factor-binding proteins. --- Cancer. --- Cancers --- Carcinoma --- Malignancy (Cancer) --- Malignant tumors --- IGF-binding proteins --- Somatomedin-binding proteins --- Medicine. --- Cancer research. --- Pharmacology. --- Biomedicine. --- Cancer Research. --- Pharmacology/Toxicology. --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemicals --- Chemotherapy --- Drugs --- Pharmacy --- Cancer research --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Pathology --- Physicians --- Physiological effect --- Carrier proteins --- Oncology. --- Toxicology. --- Pharmacology --- Poisoning --- Poisons --- Toxicology
Listing 1 - 10 of 17 | << page >> |
Sort by
|