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This volume's 598 documents span 22 April 1818 to 31 January 1819. Jefferson spends months preparing for a meeting to choose the site of the state university. He drafts the Rockfish Gap Report recommending the location of the University of Virginia at Charlottesville as well as legislation confirming this decision. Jefferson travels to Warm Springs to cure his rheumatism but instead contracts a painful infection on his buttocks. His enforced absence from Poplar Forest leads to detailed correspondence with plantation manager Joel Yancey. A work that Jefferson helped translate, Destutt de Tracy's Treatise on Political Economy, is finally published. Salma Hale visits Monticello and describes Jefferson's views on food, wine, and religion. In acknowledging an oration by Mordecai M. Noah, Jefferson remarks that the suffering of members of the Jewish faith "has furnished a remarkable proof of the universal spirit of religious intolerance." He receives long discussions of occult science and the nature of light by Robert Miller and Gabriel Crane. Abigail Adams dies, and Jefferson assures John Adams that their own demise will result in "an ecstatic meeting with the friends we have loved & lost and whom we shall still love and never lose again."

Jefferson, Thomas, --- A History of England. --- Aaron Burr. --- Abraham Gottlob Werner. --- Adelbert von Chamisso. --- Adjournment. --- Albert Gallatin. --- American Antiquarian Society. --- American Colonization Society. --- An Essay on the Principle of Population. --- Annals (Tacitus). --- Articles of Confederation. --- Battle of White Plains. --- Battles of Saratoga. --- Benjamin Vaughan. --- Bill of lading. --- Bushrod Washington. --- Button Gwinnett. --- Calculation. --- Cato the Elder. --- Charles Cotesworth Pinckney. --- Chemical Society. --- College of William & Mary. --- Confucius. --- Consideration. --- Continental Army. --- Dartmouth College. --- Dartmouth University. --- DeWitt Clinton. --- Democritus. --- Dormitory. --- Dutch West India Company. --- Edward Coles. --- Edward Rutledge. --- Future History (Heinlein). --- George Ticknor. --- George Wythe. --- Grammar school. --- Harvard University. --- Henry Dearborn. --- His Family. --- I Wish (manhwa). --- Institution. --- Invoice. --- J. (newspaper). --- James Maury. --- James Monroe. --- John A. Garraty. --- John Drayton. --- John Trumbull. --- Joseph Bonaparte. --- Joseph Priestley. --- Karl August Varnhagen von Ense. --- Letter of resignation. --- Loeb Classical Library. --- Lucretius. --- Martin Van Buren. --- Memoir. --- Mergenthaler Linotype Company. --- Mineralogy. --- N. (novella). --- Napoleon. --- Nathaniel Bowditch. --- New York Edition. --- Newspaper. --- Of Education. --- Oliver Evans. --- Pamphlet. --- Personal History. --- Political economy. --- Politique. --- Poplar Forest. --- President of the United States. --- Princeton University Press. --- Princeton University. --- Publication. --- Quantity. --- Quarterly Review. --- Red wine. --- Remittance. --- Republicanism. --- Richard Rush. --- Roman cement. --- Salary. --- Salutation. --- Statute. --- Stephen Greenblatt. --- Stephen Hopkins (Mayflower passenger). --- Surrender of Lord Cornwallis. --- Tax. --- Testimonial. --- The Philosopher. --- United States Naval Academy. --- University of Pennsylvania. --- University of Virginia. --- War pension. --- William Bartram. --- William Smith Shaw. --- William Wirt (Attorney General). --- Writing. --- Year.