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Staphylococcus epidermidis --- Bacteremia --- Bacterial Typing Techniques --- Staphylococcal Infections --- Coagulase --- isolation & purification --- microbiology --- microbiology --- metabolism

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Microbiology --- Allergy and Immunology --- Immunity --- Infection --- Communicable Diseases --- Communicable diseases --- Microbiologie --- Immunité --- Maladies infectieuses --- Periodicals. --- Périodiques --- Microbiology. --- Allergy and Immunology. --- Immunity. --- Infection. --- Communicable Diseases. --- Communicable diseases. --- Agriculture Sciences --- Health Sciences --- Life Sciences --- Soil Chemistry, Microbiology, Fertility & Fertilizers --- Allergy --- Immunology --- Micro and Molecular Biology --- bacteremia --- pneumonia --- vancomycin --- infection --- mycobacterium --- General microbiology

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The worldwide dissemination of antimicrobial-resistant bacteria, particularly those resistant to last-resource antibiotics, is a common problem to which no immediate solution is foreseen. In 2017, the World Health Organization (WHO) published a list of antimicrobial-resistant "priority pathogens", which include a group of microorganisms with high-level resistance to multiple drugs, named ESKAPE pathogens, comprising vancomycin-resistant Enterococcus faecium (VRE), methicillin- and vancomycin-resistant Staphylococcus aureus (MRSA and VRSA), extended spectrum β-lactamase (ESBL) or carbapenem-resistant Klebsiella pneumoniae, carbapenem-resistant Acinetobacter baumannii, carbapenem-resistant Pseudomonas aeruginosa and extended spectrum β-lactamase (ESBL) or carbapenem-resistant Enterobacter spp. These bacteria also have the ability to produce several virulence factors, which have a major influence on the outcomes of infectious diseases. Bacterial resistance and virulence are interrelated, since antibiotics pressure may influence bacterial virulence gene expression and, consequently, infection pathogenesis. Additionally, some virulence factors contribute to an increased resistance ability, as observed in biofilm-producing strains. The surveillance of important resistant and virulent clones and associated mobile genetic elements is essential to decision making in terms of mitigation measures to be applied for the prevention of such infections in both human and veterinary medicine, being also relevant to address the role of natural environments as important components of the dissemination cycle of these strains.

Research & information: general --- Biology, life sciences --- Microbiology (non-medical) --- biocide --- antibiotic resistance --- cross-resistance --- aminoglycoside --- adaptation --- biofilm --- pyruvate cycle --- mastitis --- staphylococci --- virulence factors --- genes --- antimicrobial resistance --- infant --- newborn --- bacteremia --- Gram-negative bacteria --- drug resistance --- microbial --- mortality --- microcosm --- Aeromonas --- climate change --- temperature --- pH --- water --- Acinetobacter baumannii --- virulence --- whole-genome sequencing --- international high-risk clones --- genomic epidemiology --- dogs --- Escherichia coli --- ESBL --- CTX-M-15 --- CTX-M-1 --- CTX-M-32 --- CTX-M-55 --- CTX-M-14 --- qAmpC --- CMY-2 --- camel --- domestic --- milk --- virulence genes --- extended-spectrum β-lactamases --- biofilm formation --- Pseudomonas aeruginosa --- carbapenem resistance --- KPC-2 --- plasmid --- diabetic foot infections --- Staphylococcus aureus --- subinhibitory concentrations --- virulence-related genes

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The worldwide dissemination of antimicrobial-resistant bacteria, particularly those resistant to last-resource antibiotics, is a common problem to which no immediate solution is foreseen. In 2017, the World Health Organization (WHO) published a list of antimicrobial-resistant "priority pathogens", which include a group of microorganisms with high-level resistance to multiple drugs, named ESKAPE pathogens, comprising vancomycin-resistant Enterococcus faecium (VRE), methicillin- and vancomycin-resistant Staphylococcus aureus (MRSA and VRSA), extended spectrum β-lactamase (ESBL) or carbapenem-resistant Klebsiella pneumoniae, carbapenem-resistant Acinetobacter baumannii, carbapenem-resistant Pseudomonas aeruginosa and extended spectrum β-lactamase (ESBL) or carbapenem-resistant Enterobacter spp. These bacteria also have the ability to produce several virulence factors, which have a major influence on the outcomes of infectious diseases. Bacterial resistance and virulence are interrelated, since antibiotics pressure may influence bacterial virulence gene expression and, consequently, infection pathogenesis. Additionally, some virulence factors contribute to an increased resistance ability, as observed in biofilm-producing strains. The surveillance of important resistant and virulent clones and associated mobile genetic elements is essential to decision making in terms of mitigation measures to be applied for the prevention of such infections in both human and veterinary medicine, being also relevant to address the role of natural environments as important components of the dissemination cycle of these strains.

biocide --- antibiotic resistance --- cross-resistance --- aminoglycoside --- adaptation --- biofilm --- pyruvate cycle --- mastitis --- staphylococci --- virulence factors --- genes --- antimicrobial resistance --- infant --- newborn --- bacteremia --- Gram-negative bacteria --- drug resistance --- microbial --- mortality --- microcosm --- Aeromonas --- climate change --- temperature --- pH --- water --- Acinetobacter baumannii --- virulence --- whole-genome sequencing --- international high-risk clones --- genomic epidemiology --- dogs --- Escherichia coli --- ESBL --- CTX-M-15 --- CTX-M-1 --- CTX-M-32 --- CTX-M-55 --- CTX-M-14 --- qAmpC --- CMY-2 --- camel --- domestic --- milk --- virulence genes --- extended-spectrum β-lactamases --- biofilm formation --- Pseudomonas aeruginosa --- carbapenem resistance --- KPC-2 --- plasmid --- diabetic foot infections --- Staphylococcus aureus --- subinhibitory concentrations --- virulence-related genes

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A screenshot of some the most rapidly evolving fields in Neonatology and Pediatrics with articles reviewing some metabolic dysregulations as well as non-oncologic diseases that may occur in infancy, childhood, youth. The illustrative material with original photographs and drawings highlighting some pathogenetic concepts are keystones of this book.

interferon signature score --- interferonopathies --- n/a --- rat model --- pulmonary hypertension --- neurological symptoms --- early-onset sarcoidosis --- sialidosis --- sialidosis I --- children --- mediastinitis --- bilirubin encephalopathy --- Blau syndrome --- myocardial dysfunction --- cardiopulmonary bypass --- neuropathology --- bacteremia --- tissue doppler imaging --- HD-OCT --- biostatistics --- continuous insulin infusion system --- infants --- RNFL --- biomarkers --- diagnosis --- somatosensory evoked potential --- Paediatric sarcoidosis --- diabetic retinopathy --- brain damage --- tonsillectomy --- hybrid closed-loop system --- cytopathology --- neuraminidase --- subcutaneous emphysema --- continuous glucose monitor --- respiratory syncytial virus --- data sharing --- complication --- lysosomal storage disease --- echocardiography --- ONH --- systemic lupus erythematosus --- NT-proBNP --- preterm brain --- head and neck --- inter-laboratory variability --- GSH --- insulin pump --- high-risk sarcoidosis --- type 1 diabetes --- hypoxia-ischemia --- Tei index --- sialidosis II --- mediastinal emphysema --- newborn --- diabetes technology --- diagnostics --- lysosomal exocytosis --- kernicterus --- cerebral palsy --- choroidal thickness --- oxidative stress --- Children --- Pediatrics. --- Diseases. --- Paediatrics --- Pediatric medicine --- Medicine --- Childhood diseases --- Children's diseases --- Diseases of children --- Juvenile diseases --- Pediatrics --- Diseases --- Health and hygiene