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2022 (4)

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Book
Utility of Bromelain and N-Acetylcysteine in Treatment of Peritoneal Dissemination of Gastrointestinal Mucin-Producing Malignancies
Authors: --- ---
ISBN: 3319285688 331928570X Year: 2016 Publisher: Cham : Springer International Publishing : Imprint: Springer,

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This volume will describe both growth-inhibitory and mucin-depleting effects of bromelain and N-acetylcysteine, on their own or in combination, in cancer. It will coherently review the pathophysiological aspects of the mucin glycoproteins in malignancies and provide an updated account of the status of bromelain and N-acetylcysteine in cancer therapy. The volume will develop the idea of using these two drugs as a combination formulation for mucin-depleting effects. .


Book
Functional Polymers as Innovative Tools in the Delivery of Antimicrobial Agents
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Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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This Special Issue explored different topics concerning recent progress in the synthesis and characterization of suitable innovative macromolecular systems, proposed as carriers of specific antimicrobial molecules, to be employed in the biomedical and pharmaceutical fields. Many infectious diseases are induced by omnipresent micro-organisms, including bacteria, viruses, protozoa, fungi, and algae, and, consequently, are very common, accounting for a significant share of the global disease burden. Unfortunately, antimicrobial resistance, adverse effects, and the high cost of antimicrobials are crucial health challenges worldwide. One of the common efforts in addressing this issue lies in improving the existing antimicrobial delivery systems. In this regard, nanoparticles as well as three-dimensional hydrophilic systems represent valuable tools able to ensure excellent performances. Biocompatible polymeric particles, entrapping these bioactive molecules, are capable of releasing them over a desired period of time, thereby decreasing the frequency of their administration. At the same time, these systems are able to protect antimicrobial drugs from degradation, enhancing their bioavailability. This Special Issue serves to highlight and capture the contemporary progress recorded in this field.


Book
Functional Polymers as Innovative Tools in the Delivery of Antimicrobial Agents
Author:
Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

This Special Issue explored different topics concerning recent progress in the synthesis and characterization of suitable innovative macromolecular systems, proposed as carriers of specific antimicrobial molecules, to be employed in the biomedical and pharmaceutical fields. Many infectious diseases are induced by omnipresent micro-organisms, including bacteria, viruses, protozoa, fungi, and algae, and, consequently, are very common, accounting for a significant share of the global disease burden. Unfortunately, antimicrobial resistance, adverse effects, and the high cost of antimicrobials are crucial health challenges worldwide. One of the common efforts in addressing this issue lies in improving the existing antimicrobial delivery systems. In this regard, nanoparticles as well as three-dimensional hydrophilic systems represent valuable tools able to ensure excellent performances. Biocompatible polymeric particles, entrapping these bioactive molecules, are capable of releasing them over a desired period of time, thereby decreasing the frequency of their administration. At the same time, these systems are able to protect antimicrobial drugs from degradation, enhancing their bioavailability. This Special Issue serves to highlight and capture the contemporary progress recorded in this field.


Book
Functional Polymers as Innovative Tools in the Delivery of Antimicrobial Agents
Author:
Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

This Special Issue explored different topics concerning recent progress in the synthesis and characterization of suitable innovative macromolecular systems, proposed as carriers of specific antimicrobial molecules, to be employed in the biomedical and pharmaceutical fields. Many infectious diseases are induced by omnipresent micro-organisms, including bacteria, viruses, protozoa, fungi, and algae, and, consequently, are very common, accounting for a significant share of the global disease burden. Unfortunately, antimicrobial resistance, adverse effects, and the high cost of antimicrobials are crucial health challenges worldwide. One of the common efforts in addressing this issue lies in improving the existing antimicrobial delivery systems. In this regard, nanoparticles as well as three-dimensional hydrophilic systems represent valuable tools able to ensure excellent performances. Biocompatible polymeric particles, entrapping these bioactive molecules, are capable of releasing them over a desired period of time, thereby decreasing the frequency of their administration. At the same time, these systems are able to protect antimicrobial drugs from degradation, enhancing their bioavailability. This Special Issue serves to highlight and capture the contemporary progress recorded in this field.


Book
Synthesis, Study and Utilization of Natural Products
Authors: ---
ISBN: 3039281534 3039281526 Year: 2020 Publisher: MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

Natural products and the preparations based on them play a stable and ever-increasing role in human and veterinary medicine, agriculture, in food and the cosmetic industry, and in an increasing number of other fields. Their importance is based on the fact that they are mostly bound to renewable sources, which in fact makes them valuable within a circular economy, inter alia. At the same time, natural products provide the origin of stereochemistry, optical activity, regioselectivity, chirality, and many other concepts and directions within science, development, and industry in a scope, which is indispensable. They serve as a constant powerful stimulus and model that inspires researchers to create new effective tools, similar to natural ones, for controlling bioregulation mechanisms and solving practical problems. This was the reason for organizing this Special Issue aimed at underlining the current developments in all the fields connected to natural products.

Keywords

varioxiranol A --- natural enantiomer --- n/a --- ribosomally synthesized --- triterpenoids --- apo-CpcB --- water resistance --- radical scavenger --- bardoxolone methyl --- antioxidant activity --- octadecanoid --- derivatives --- inhibitor --- chlorogenic acid --- biosynthesis --- microbial biosynthesis --- flow cytometry --- adhesive --- phycocyanin --- antioxidant --- anticancer drug --- resource chemistry --- ginkgolide --- anti-inflammation --- salt stress --- polyphenol --- synthesis of natural products --- rheumatoid arthritis --- PEGylated purpurin 18 --- photosensitizer --- RiPP --- isosorbide --- bioactivity --- cell opening --- stilbene --- tea tussock moth --- flavonoids --- flexible polyurethane foam --- gene expression --- genetical transformation --- research progress --- oleic acid-elicited --- pharmacokinetic features --- phenolic acid --- Plantago depressa --- platelet-activating factor receptor --- photodynamic therapy --- fatty acid --- soy protein isolate --- apoptosis --- HepG2 cells --- cancer cells --- live-cell fluorescence microscopy --- tomato --- caffeoylquinic acids --- pinocembrin --- insect sex pheromone --- 4-epi-varioxiranol A --- natural products --- singlet oxygen --- total synthesis --- lipid-lowering effects --- reversible urethane linkages --- cytotoxicity --- bromelain --- Ramulus mori --- polysaccharides --- SlCOMT1 --- pharmacological activities --- absolute structure --- natural product --- mitochondria --- Emericella variecolor --- triglycidylamine --- Spirulina --- viscosity --- post-translationally modified peptides --- phototoxicity --- melatonin


Book
A History of Burn Care
Authors: ---
Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Burn injuries are still one of the most common and devastating injuries in human and the treatment of major burns remains a major challenge for physicians worldwide. Modern burn care involves many components from initial first aid, burn size and burn depth assessment, fluid resuscitation, wound care, excision and grafting/ coverage, infection control and nutritional support. Progress in each of these areas has contributed significantly to the overall enhanced survival of burn victims of the past decades. Most major advances in burn care occurred in the past 50 years, spurred on by wars and great fires. The use of systemic antibiotics and topical antiinfective agents greatly reduced sepsis related mortality. This along with the improvement of new surgical and skin grafting techniques allowed the earlier excision and coverage of deep burns which resulted in greatly improved survival rates and better functional and aesthetic outcome. In this book we look back at how the treatment of burns has evolved over the past decades and hundreds of years. The advancement of burn care has been closely associated with our deeper understanding of its pathophysiology; we have now come to understand the impact that burn injuries have in the multiple fields of current medical science i.e. in metabolism and circulation, electrolyte balance and nutrition, immunology and infection, inflammation, pulmonary function and wound healing.


Book
A History of Burn Care
Authors: ---
Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

Burn injuries are still one of the most common and devastating injuries in human and the treatment of major burns remains a major challenge for physicians worldwide. Modern burn care involves many components from initial first aid, burn size and burn depth assessment, fluid resuscitation, wound care, excision and grafting/ coverage, infection control and nutritional support. Progress in each of these areas has contributed significantly to the overall enhanced survival of burn victims of the past decades. Most major advances in burn care occurred in the past 50 years, spurred on by wars and great fires. The use of systemic antibiotics and topical antiinfective agents greatly reduced sepsis related mortality. This along with the improvement of new surgical and skin grafting techniques allowed the earlier excision and coverage of deep burns which resulted in greatly improved survival rates and better functional and aesthetic outcome. In this book we look back at how the treatment of burns has evolved over the past decades and hundreds of years. The advancement of burn care has been closely associated with our deeper understanding of its pathophysiology; we have now come to understand the impact that burn injuries have in the multiple fields of current medical science i.e. in metabolism and circulation, electrolyte balance and nutrition, immunology and infection, inflammation, pulmonary function and wound healing.


Book
A History of Burn Care
Authors: ---
Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

Burn injuries are still one of the most common and devastating injuries in human and the treatment of major burns remains a major challenge for physicians worldwide. Modern burn care involves many components from initial first aid, burn size and burn depth assessment, fluid resuscitation, wound care, excision and grafting/ coverage, infection control and nutritional support. Progress in each of these areas has contributed significantly to the overall enhanced survival of burn victims of the past decades. Most major advances in burn care occurred in the past 50 years, spurred on by wars and great fires. The use of systemic antibiotics and topical antiinfective agents greatly reduced sepsis related mortality. This along with the improvement of new surgical and skin grafting techniques allowed the earlier excision and coverage of deep burns which resulted in greatly improved survival rates and better functional and aesthetic outcome. In this book we look back at how the treatment of burns has evolved over the past decades and hundreds of years. The advancement of burn care has been closely associated with our deeper understanding of its pathophysiology; we have now come to understand the impact that burn injuries have in the multiple fields of current medical science i.e. in metabolism and circulation, electrolyte balance and nutrition, immunology and infection, inflammation, pulmonary function and wound healing.


Book
Valorization of Food Processing By-Products
Authors: --- ---
ISBN: 3036559507 3036559493 Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

The papers published in this Special Issue report on recent studies investigating the exploitation of by-products produced by the food industry. The topics investigated include the extraction setups used for valuable food waste by-products and their applications as adjuncts to food preparation; the appropriate selection of solvents and extraction processes; and the interactions between extracted fractions and supplementary foods. The papers evaluate a wide variety of foodstuffs and provide results regarding the extension their shelf-lives and activities as functional foods.

Keywords

Research & information: general --- Biology, life sciences --- Technology, engineering, agriculture --- by-product --- rheological properties --- optimization --- melting profile --- antioxidant activity --- mayonnaise --- olive mill wastewater --- oxidative stability --- phenolic extract --- pork --- fatty acid --- amino acid --- mineral --- meat --- sustainability --- spent biomass --- prebiotic potential --- enzymatic digestion --- biorefinery --- circular economy --- by-products --- ovine scotta --- bioactive peptides --- bromelain --- pancreatin --- dipeptidyl peptidase IV inhibition --- ovine second whey cheese --- enzymatic hydrolysis --- wasted bread --- bioprocessing --- lactic acid bacteria --- soil amendment --- byproducts --- vegetable oil industry --- phenolics --- flavonoids --- photochemiluminescence --- cold-pressed oil by-product --- gum --- thixotropic behavior --- low-fat vegan mayonnaise --- thickeners --- gelling agents --- tomato pomace --- lycopene --- β-carotene --- extraction --- food by-products --- deep eutectic solvents --- non-thermal drying --- stilbene --- vine shoots --- viticulture waste --- trans-resveratrol --- ε-viniferin --- Italian varieties --- no-waste --- omega-3 --- smart sensors --- reuse --- fish oil industry --- recovery --- chemometrics --- lipid profile --- aquafaba --- cold-pressed oils --- confocal laser scanning microscopy --- egg replacement --- physicochemical properties --- radical scavenging activity --- vegan mayonnaise --- Amberlite resin --- hazelnut skin --- polyphenols --- Pinot noir pomace --- solid–liquid extraction --- valorization --- fatty acids --- derivatization --- cranberry pomace --- dietary fiber --- technological properties --- kiwi byproducts --- probiotic --- prebiotic --- Lactobacillus casei --- ingredients --- functional foods --- microbial spoilage --- lipidic oxidation --- antioxidant --- predictive microbiology --- food preservation --- food safety --- sustainable strategy --- by-product reuse --- kinetic parameters --- Olea europaea --- waste reuse --- inulin --- high polymerization degree --- functional pasta --- glycemic index --- prebiotics growth --- n/a --- solid-liquid extraction


Book
Physicochemical, Sensory and Nutritional Properties of Foods Affected by Processing and Storage
Authors: ---
Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Processing and storage can cause changes and interactions in food components that have effects on nutritional value, organoleptic characteristics or even food safety. This book includes 19 research works showing important and interesting advances, as well as new approaches, in this research topic. Four articles are dedicated to studying the effect of canning conditions (filling media and some ingredients) on the diverse parameters of quality for fish and pet foods. Three articles are devoted to studying the effects of dehydration (pre-treatments and drying procedures). One article is dedicated to monitoring the elaboration of a fermented and dehydrated product (sausage) using a portable NIRS device. The ninth article of this book studies the effect of low-dose electron beam irradiation on cooking quality, moisture migration, and thermodynamics, as well as the digestion properties of the isolated starches in newly harvested and dried rice. The next contribution studies the use of different preservatives to avoid the formation of undesirable volatile organic compounds in stracciatella cheese. Another article examines the impact of source material, kibble size, temperature, and duration on the efficiency of the aqueous extraction of sugars and phenolics from carob kibbles by conventional heat-assisted (HAE) and ultrasound-assisted (UAE) methods. In two articles, marinating with different extracts, alone or combined with other seasoning/conditioning methods, was essayed to tenderize beef or to improve the sensory quality of chicken leg and breast meat. The effect of various cooking methods on the quality, structure, pasting, water distribution and protein oxidation of fish and meat-based snacks is studied in the fourteenth article. The last five articles are dedicated to the study of the effects of storage on several foods (olive oil, blueberry, beetroot and Atlantic mackerel).

Keywords

Research & information: general --- Electron Beam Irradiation --- rice --- moisture --- physicochemical properties --- rabbiteye blueberry --- postharvest storage --- firmness --- aroma compounds --- off-odor --- dry-fermented sausages --- near infrared spectroscopy --- portable device --- PLS-DA --- Scomber colias --- prior chilling --- Fucus spiralis --- packaging medium --- canning --- lipid damage --- colour --- trimethylamine --- quality --- carob kibbles --- carob juice --- aqueous extraction --- sugars --- phenolics --- free amino acids --- biogenic amines --- filling medium --- European eels --- stracciatella cheese --- volatile organic compounds --- sensory characteristics --- natural preservatives --- cheese storage --- pineapple by-products --- hydrostatic pressure --- bromelain --- enzyme activity --- marinade --- meat --- texture --- water status and distribution --- microstructure --- secondary structure of protein --- Atlantic mackerel --- saffron quality --- secondary metabolites --- drying --- high performance liquid chromatography-diode array detection (HPLC-DAD) --- spectrophotometry --- canned eels --- olive oil --- sunflower oil --- oxidation --- antioxidants --- total phenols --- vitamin E --- fresh wet noodles --- humidity-controlled dehydration --- microorganisms --- shelf-life --- noodle quality --- “Rocha” pear --- ultrasound --- microwave --- quality characteristics --- empirical models --- beetroot --- organic farming --- storage --- bioactive compounds --- betalain --- nitrate --- sugar --- phenolic compounds --- total dry matter --- chicken meat --- sensory evaluation --- superheated steam --- marination --- hot smoking --- storage effect --- extra virgin olive oil --- phenols --- sterols --- tocopherols --- temperature --- argon --- freeze-thaw cycles --- anthocyanins --- gas chromatography-mass spectrometry --- aroma profiles --- hot-air drying --- blueberry --- cooking methods --- fish meat snacks --- LF-NMR --- SEM --- protein oxidation --- expressible moisture --- gel --- gum --- heat penetration --- thermally processed --- wet pet food --- n/a --- "Rocha" pear

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