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Datenqualität in der medizinischen Forschung
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ISBN: 3954663740 3954661217 Year: 2014 Publisher: Berlin MWV Medizinisch Wissenschaftliche Verlagsgeschellschaft

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The benefit of cohort studies and registers in patient-oriented collaborative research depends largely on the quality of the data recorded there. Supply and quality research depend on scientifically proven methods and procedures to ensure high data quality. This guideline contains corresponding recommendations for the management of data quality in registers, cohort studies and data repositories. In the second edition, a significantly expanded set of indicators is provided and the use of the indicators is described as an example for different types of empirical research projects. The guideline is rounded off by a current literature review and analysis. It is therefore an important part of the range of measures to improve and ensure data quality in medical research.


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Public health interventions to reduce the secondary spread of measles
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Year: 2015 Publisher: Ottawa, ON : Canadian Agency for Drugs and Technologies in Health,

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Streptococcal antigen test for pneumonia detection : a review of clinical and cost-effectiveness and guidelines
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Year: 2015 Publisher: Ottawa, ON : Canadian Agency for Drugs and Technologies in Health,

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Antibiotic impregnated cement for primary hip or knee arthroplasty : a review of the clinical and cost-effectiveness
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Year: 2015 Publisher: Ottawa (ON) : Canadian Agency for Drugs and Technologies in Health,

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Valganciclovir for off-label indications : a review of clinical effectiveness
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Year: 2015 Publisher: Ottawa (ON) : Canadian Agency for Drugs and Technologies in Health,


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Transcatheter aortic valve replacement in severe aortic stenosis : a review of comparative durability and clinical effectiveness beyond 12 months
Authors: --- ---
Year: 2013 Publisher: Ottawa (ON) : Canadian Agency for Drugs and Technologies in Health,


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Autologous fat grafting for reconstructive surgery : a review of the clinical and cost-effectiveness
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Year: 2014 Publisher: Ottawa, Ontario : Canadian Agency for Drugs and Technologies in Health,

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"Research questions. 1. What is the clinical effectiveness of autologous fat grafting for reconstructive surgery? 2. What is the cost-effectiveness of autologous fat grafting for reconstructive surgery?"--Page 2.


Book
Periodic dental examinations for oral health : a review of clinical effectiveness, cost effectiveness, and guidelines
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Year: 2014 Publisher: Ottawa, Ontario : Canadian Agency for Drugs and Technologies in Health,

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"Research questions. 1. What is the comparative clinical evidence for dental examinations every 12 months compared with other intervals for the prevention of oral disease? 2. What is the cost-effectiveness of dental examinations every 12 months compared with other intervals for the prevention of oral disease? 3. What are the evidence-based guidelines regarding the frequency of routine dental examinations for prevention of oral disease?"--Page 2.


Book
Radiation emissions from computed tomography : a review of the risk of cancer and guidelines
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Year: 2014 Publisher: Ottawa, Ontario : Canadian Agency for Drugs and Technologies in Health,

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Reviews the evidence on the risk of cancer associated with CT exposure and recommended threshold of radiation doses.


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Debridement procedures for managing diabetic foot ulcers : a review of clinical effectiveness, cost-effectiveness, and guidelines
Authors: ---
Year: 2014 Publisher: [Ottawa, Ontario] : Canadian Agency for Drugs and Technologies in Health,

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Debridement is the removal of necrotic tissue, foreign debris, bacterial growth, callus, wound edge, and wound bed tissue from chronic wounds in order to stimulate the wound healing process. Stimulation of wound healing mediated by debridement is thought to occur by the conversion of a chronic non-healing wound environment to an acute healing environment through the removal of cells that are not responsive to endogenous healing stimuli. Debridement is used commonly in standard wound treatment of diabetic foot ulcers (DFUs). Methods of debridement include surgery (sharp debridement), chemical debridement (antiseptics, polysaccharide beads, pastes), autolytic (hydrogels, hydrocolloids and transparent films), biosurgery (maggots), mechanical (hydrodebridement), and biochemical debridement (enzyme preparations). Callus is a buildup of keratinized skin formed under conditions of repeated pressure or friction and may contribute to ulcer formation by creating focal areas of high plantar pressure. The debridement of callus has been proposed to be relevant for both treatment and prevention of DFU. The purpose of this report is to retrieve and review existing evidence of comparative clinical effectiveness of different methods of debridement for the treatment of DFUs. Additionally examined in this report is the clinical effectiveness for treatment and prevention of DFU using callus debridement. Cost-effectiveness, and existing debridement guidelines for the treatment of DFUs will also be reviewed.

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