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The benefit of cohort studies and registers in patient-oriented collaborative research depends largely on the quality of the data recorded there. Supply and quality research depend on scientifically proven methods and procedures to ensure high data quality. This guideline contains corresponding recommendations for the management of data quality in registers, cohort studies and data repositories. In the second edition, a significantly expanded set of indicators is provided and the use of the indicators is described as an example for different types of empirical research projects. The guideline is rounded off by a current literature review and analysis. It is therefore an important part of the range of measures to improve and ensure data quality in medical research.
Medicine --- Research --- Methodology. --- Health Workforce --- Epidemiology & medical statistics --- data repository --- source data verification --- cohort study --- quality indicators
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Measles --- Communicable diseases --- Vaccination. --- Prevention. --- Clinical medicine --- Cohort study --- Epidemiology --- Health --- Health care --- Health sciences --- Immunization --- Immunology --- Medical humanities
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Pneumonia --- Outcome assessment (Medical care) --- Diagnosis. --- Streptococcal infections --- Antibiotics --- Bias --- Clinical medicine --- Clinical trial --- Cohort study --- Evidence-based medicine --- Experiment --- Health --- Health care --- Health sciences
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Bone cements. --- Total hip replacement. --- Total knee replacement. --- Antibiotics. --- Adverse effect --- Akaike information criterion --- Antibiotics --- Bias --- Clinical trial --- Cohort study --- Comorbidity --- Confidence interval --- Confounding --- Evaluation
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Outcome assessment (Medical care) --- Valganciclovir --- Cytomegalovirus infections --- Chronic fatigue syndrome --- Clinical medicine --- Cohort study --- Confounding --- External validity --- Ganciclovir --- Glioblastoma --- Health --- Health care --- Health sciences --- Therapeutic use. --- Chemotherapy.
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Cardiac catheterization. --- Aortic valve --- Heart valve prosthesis. --- Aortic Valve Stenosis --- Heart Valve Prosthesis Implantation. --- Heart Catheterization. --- Aortic Valve --- Aortic stenosis --- Blinded experiment --- Clinical trial --- Cohort study --- Health --- Health care --- Health sciences --- Medicine --- Medline --- Stenosis --- surgery. --- transplantation.
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"Research questions. 1. What is the clinical effectiveness of autologous fat grafting for reconstructive surgery? 2. What is the cost-effectiveness of autologous fat grafting for reconstructive surgery?"--Page 2.
Breast --- Breast implants. --- Cancer. --- Mammaplasty --- Adipose tissues --- Adipose Tissue --- Cost-Benefit Analysis. --- Breast augmentation --- Breast cancer --- Breast implant --- Breast reconstruction --- Cancer --- Clinical trial --- Cohort study --- Health --- Health sciences --- Mastectomy --- Complications --- Transplantation. --- Cost effectiveness. --- methods. --- transplantation.
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"Research questions. 1. What is the comparative clinical evidence for dental examinations every 12 months compared with other intervals for the prevention of oral disease? 2. What is the cost-effectiveness of dental examinations every 12 months compared with other intervals for the prevention of oral disease? 3. What are the evidence-based guidelines regarding the frequency of routine dental examinations for prevention of oral disease?"--Page 2.
Dental therapeutics. --- Dental care. --- Preventive dentistry --- Preventive Dentistry --- Cost-Benefit Analysis. --- Clinical trial --- Cohort study --- Dentistry --- Evidence-based medicine --- Health --- Health care --- Health sciences --- Human tooth --- Medical specialties --- Medicine --- Evaluation. --- Cost effectiveness. --- methods. --- economics.
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Reviews the evidence on the risk of cancer associated with CT exposure and recommended threshold of radiation doses.
Radiation --- Dosage. --- Tomography --- Tomography, X-Ray Computed. --- Radiation Dosage. --- Risk Assessment. --- Absorbed dose --- Cancer --- Clinical medicine --- Cohort study --- Ct scan --- Health --- Health sciences --- Ionizing radiation --- Medical imaging --- Medical specialties --- Safety measures.
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Debridement is the removal of necrotic tissue, foreign debris, bacterial growth, callus, wound edge, and wound bed tissue from chronic wounds in order to stimulate the wound healing process. Stimulation of wound healing mediated by debridement is thought to occur by the conversion of a chronic non-healing wound environment to an acute healing environment through the removal of cells that are not responsive to endogenous healing stimuli. Debridement is used commonly in standard wound treatment of diabetic foot ulcers (DFUs). Methods of debridement include surgery (sharp debridement), chemical debridement (antiseptics, polysaccharide beads, pastes), autolytic (hydrogels, hydrocolloids and transparent films), biosurgery (maggots), mechanical (hydrodebridement), and biochemical debridement (enzyme preparations). Callus is a buildup of keratinized skin formed under conditions of repeated pressure or friction and may contribute to ulcer formation by creating focal areas of high plantar pressure. The debridement of callus has been proposed to be relevant for both treatment and prevention of DFU. The purpose of this report is to retrieve and review existing evidence of comparative clinical effectiveness of different methods of debridement for the treatment of DFUs. Additionally examined in this report is the clinical effectiveness for treatment and prevention of DFU using callus debridement. Cost-effectiveness, and existing debridement guidelines for the treatment of DFUs will also be reviewed.
Diabetic Foot --- Debridement --- Treatment Outcome --- Cost-Benefit Analysis --- surgery. --- economics. --- methods. --- Canada --- Foot --- Debridement. --- Diabetes --- Wireless communication systems --- Patient monitoring --- Foot Ulcer --- Diabetes Complications --- Chronic wound --- Clinical medicine --- Clinical trial --- Cohort study --- Diabetic foot ulcer --- Health --- Health care --- Health sciences --- Medical guideline --- Ulcers --- Complications --- Safety measures. --- Equipment and supplies. --- therapy.
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