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Marine biotoxins may pose a threat to the human consumption of seafood and seafood products. The increasing global trade and higher demand for seafood products worldwide represents a challenge for food safety authorities, policy makers, food business operators, and the scientific community, in particular, researchers devoted to environmental sciences, toxicology, and analytical chemistry. In addition, due to changes in climate conditions and technological developments, new and emerging marine toxins are being detected in regions where they were previously unknown. This Special Issue highlight studies aiming to the develop detection methods for marine biotoxins for better understanding the dynamics of accumulation/elimination of marine biotoxins and their effects on marine organisms, as well as toxin exposure studies that aim to evaluate the risks associated with the consumption of contaminated seafood.
mass mortality --- marine biotoxin --- n/a --- alamethicin --- synergy --- seafood toxin --- patulin --- Paralytic shellfish toxin --- greater blue-ringed octopus --- Alexandrium catenella --- paralytic toxicity --- Ishigaki Island --- depuration --- okadaic acid --- serum biomarker --- ecotoxicological responses --- Hapalochlaena lunulata --- sydowinin A --- purification --- PSP outbreak --- southern Chile --- posterior salivary gland --- saxitoxin --- harmful algal blooms --- gliotoxin --- seafood safety --- uptake --- immunoaffinity column --- Alexandrium --- sydowinol --- chronic exposure --- environmental neurotoxin --- assimilation --- shellfish --- LC-MS --- biotransformation --- Perna viridis --- domoic acid --- fish --- algal toxin --- warming --- tetrodotoxin --- Mesodesma donacium --- combination index --- ultrahigh high performance liquid chromatography tandem mass spectrometry
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Mycotoxins are a Public Health concern that in last year have reached the top 10 food and product hazard categories in the Rapid Alert System for Food and Feed (RASFF), with almost six hundred notifications. The toxicological effects of mycotoxins are evaluated through the extrapolation of results from in vivo and in vitro assays. Studies of mycotoxins’ effects at the cellular level precede those in organs and systems. All these studies are key steps for risk assessment and following legislation for mycotoxins. This Special Issue of Toxins comprises 10 original contributions and two reviews. The Issue reports new findings regarding toxic mechanisms, the use of innovative techniques to study the potential toxicity of mycotoxins not only individually but in combination, reflecting a real scenario according to current studies of mycotoxins.
Medicine --- Destruxin A --- Bombyx mori --- binding protein --- BmTudor-sn --- Bm12 cell --- Ochratoxin A (OTA) --- human Stem Cells --- mycotoxins --- cells --- cytotoxicity --- cell culture --- T-2 toxin --- HT-2 toxin --- apoptosis --- autophagy --- endophyte --- fungi --- neurotoxin --- lolitrems --- ochratoxin A --- beauvericin --- mixtures --- HepG2 cells --- genotoxicity --- cell cycle --- Fusarium --- Aspergillus --- Penicillium --- Alternaria --- emerging mycotoxin --- in vitro --- IPEC-J2 --- occurrence data --- trichothecene --- biosynthetic pathway --- acetyltransferase --- deacetylase --- deoxynivalenol --- 3-acetyldeoxynivalenol --- isotrichodermol --- isotrichodermin --- differentiated Caco-2 cells --- cell apoptosis --- transcriptome analysis --- hepatocyte --- chicken --- acute toxicity --- combined toxicity --- cell protection --- silibinin --- in silico prediction --- co-culture models --- mycotoxin interaction --- Loewe additivity --- combination index --- isobologram --- Chou-Talalay method --- MixLow --- IPEC-J2 cells --- RNA-seq --- inflammation --- MAPKs --- n/a --- Medicine.
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Mycotoxins are a Public Health concern that in last year have reached the top 10 food and product hazard categories in the Rapid Alert System for Food and Feed (RASFF), with almost six hundred notifications. The toxicological effects of mycotoxins are evaluated through the extrapolation of results from in vivo and in vitro assays. Studies of mycotoxins’ effects at the cellular level precede those in organs and systems. All these studies are key steps for risk assessment and following legislation for mycotoxins. This Special Issue of Toxins comprises 10 original contributions and two reviews. The Issue reports new findings regarding toxic mechanisms, the use of innovative techniques to study the potential toxicity of mycotoxins not only individually but in combination, reflecting a real scenario according to current studies of mycotoxins.
Medicine --- Destruxin A --- Bombyx mori --- binding protein --- BmTudor-sn --- Bm12 cell --- Ochratoxin A (OTA) --- human Stem Cells --- mycotoxins --- cells --- cytotoxicity --- cell culture --- T-2 toxin --- HT-2 toxin --- apoptosis --- autophagy --- endophyte --- fungi --- neurotoxin --- lolitrems --- ochratoxin A --- beauvericin --- mixtures --- HepG2 cells --- genotoxicity --- cell cycle --- Fusarium --- Aspergillus --- Penicillium --- Alternaria --- emerging mycotoxin --- in vitro --- IPEC-J2 --- occurrence data --- trichothecene --- biosynthetic pathway --- acetyltransferase --- deacetylase --- deoxynivalenol --- 3-acetyldeoxynivalenol --- isotrichodermol --- isotrichodermin --- differentiated Caco-2 cells --- cell apoptosis --- transcriptome analysis --- hepatocyte --- chicken --- acute toxicity --- combined toxicity --- cell protection --- silibinin --- in silico prediction --- co-culture models --- mycotoxin interaction --- Loewe additivity --- combination index --- isobologram --- Chou-Talalay method --- MixLow --- IPEC-J2 cells --- RNA-seq --- inflammation --- MAPKs --- n/a --- Medicine.
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Mycotoxins are a Public Health concern that in last year have reached the top 10 food and product hazard categories in the Rapid Alert System for Food and Feed (RASFF), with almost six hundred notifications. The toxicological effects of mycotoxins are evaluated through the extrapolation of results from in vivo and in vitro assays. Studies of mycotoxins’ effects at the cellular level precede those in organs and systems. All these studies are key steps for risk assessment and following legislation for mycotoxins. This Special Issue of Toxins comprises 10 original contributions and two reviews. The Issue reports new findings regarding toxic mechanisms, the use of innovative techniques to study the potential toxicity of mycotoxins not only individually but in combination, reflecting a real scenario according to current studies of mycotoxins.
Destruxin A --- Bombyx mori --- binding protein --- BmTudor-sn --- Bm12 cell --- Ochratoxin A (OTA) --- human Stem Cells --- mycotoxins --- cells --- cytotoxicity --- cell culture --- T-2 toxin --- HT-2 toxin --- apoptosis --- autophagy --- endophyte --- fungi --- neurotoxin --- lolitrems --- ochratoxin A --- beauvericin --- mixtures --- HepG2 cells --- genotoxicity --- cell cycle --- Fusarium --- Aspergillus --- Penicillium --- Alternaria --- emerging mycotoxin --- in vitro --- IPEC-J2 --- occurrence data --- trichothecene --- biosynthetic pathway --- acetyltransferase --- deacetylase --- deoxynivalenol --- 3-acetyldeoxynivalenol --- isotrichodermol --- isotrichodermin --- differentiated Caco-2 cells --- cell apoptosis --- transcriptome analysis --- hepatocyte --- chicken --- acute toxicity --- combined toxicity --- cell protection --- silibinin --- in silico prediction --- co-culture models --- mycotoxin interaction --- Loewe additivity --- combination index --- isobologram --- Chou-Talalay method --- MixLow --- IPEC-J2 cells --- RNA-seq --- inflammation --- MAPKs --- n/a --- Medicine.
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