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Frontiers in laboratory medicine
ISSN: 25423649 Year: 2017 Publisher: Beijing, China Ke Ai


Book
Water and sanitation to reduce child mortality : The impact and cost of water and sanitation infrastructure
Authors: ---
Year: 2011 Publisher: Washington, D.C., The World Bank,

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Abstract

Using household survey data, this paper estimates the mortality impact of improved water and sanitation access in order to evaluate the potential contribution of water and sanitation investment toward achieving the child mortality targets defined in Millennium Development Goal 4. The authors find that the average mortality reduction achievable by investment in water and sanitation infrastructure is 25 deaths per 1,000 children born across countries, a difference that accounts for about 40 percent of the gap between current child mortality rates and the 2015 target set in the Millennium Development Goals. According to the estimates, full household coverage with water and sanitation infrastructure could lead to a total reduction of 2.2 million child deaths per year in the developing world. Combining this analysis with cost data for water and sanitation infrastructure, the authors estimate that the average cost per life-year saved ranges between 65 and 80 percent of developing countries' annual gross domestic product per capita. The results suggest that investment in water and sanitation is a highly cost-effective policy option, even when only the mortality benefits are taken into consideration. Taking into account the additional expected benefits, such as reduced morbidity, time spending, and environmental hazards, would further increase the benefit-cost ratio.


Book
Water and sanitation to reduce child mortality : The impact and cost of water and sanitation infrastructure
Authors: ---
Year: 2011 Publisher: Washington, D.C., The World Bank,

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Abstract

Using household survey data, this paper estimates the mortality impact of improved water and sanitation access in order to evaluate the potential contribution of water and sanitation investment toward achieving the child mortality targets defined in Millennium Development Goal 4. The authors find that the average mortality reduction achievable by investment in water and sanitation infrastructure is 25 deaths per 1,000 children born across countries, a difference that accounts for about 40 percent of the gap between current child mortality rates and the 2015 target set in the Millennium Development Goals. According to the estimates, full household coverage with water and sanitation infrastructure could lead to a total reduction of 2.2 million child deaths per year in the developing world. Combining this analysis with cost data for water and sanitation infrastructure, the authors estimate that the average cost per life-year saved ranges between 65 and 80 percent of developing countries' annual gross domestic product per capita. The results suggest that investment in water and sanitation is a highly cost-effective policy option, even when only the mortality benefits are taken into consideration. Taking into account the additional expected benefits, such as reduced morbidity, time spending, and environmental hazards, would further increase the benefit-cost ratio.


Book
Remote Sensing of Savannas and Woodlands
Author:
Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Savannas and woodlands are one of the most challenging targets for remote sensing. This book provides a current snapshot of the geographical focus and application of the latest sensors and sensor combinations in savannas and woodlands. It includes feature articles on terrestrial laser scanning and on the application of remote sensing to characterization of vegetation dynamics in the Mato Grosso, Cerrado and Caatinga of Brazil. It also contains studies focussed on savannas in Europe, North America, Africa and Australia. It should be important reading for environmental practitioners and scientists globally who are concerned with the sustainability of the global savanna and woodland biome.


Book
Remote Sensing of Savannas and Woodlands
Author:
Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

Savannas and woodlands are one of the most challenging targets for remote sensing. This book provides a current snapshot of the geographical focus and application of the latest sensors and sensor combinations in savannas and woodlands. It includes feature articles on terrestrial laser scanning and on the application of remote sensing to characterization of vegetation dynamics in the Mato Grosso, Cerrado and Caatinga of Brazil. It also contains studies focussed on savannas in Europe, North America, Africa and Australia. It should be important reading for environmental practitioners and scientists globally who are concerned with the sustainability of the global savanna and woodland biome.


Book
Remote Sensing of Savannas and Woodlands
Author:
Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

Savannas and woodlands are one of the most challenging targets for remote sensing. This book provides a current snapshot of the geographical focus and application of the latest sensors and sensor combinations in savannas and woodlands. It includes feature articles on terrestrial laser scanning and on the application of remote sensing to characterization of vegetation dynamics in the Mato Grosso, Cerrado and Caatinga of Brazil. It also contains studies focussed on savannas in Europe, North America, Africa and Australia. It should be important reading for environmental practitioners and scientists globally who are concerned with the sustainability of the global savanna and woodland biome.


Book
Energy and Seismic Renovation Strategies for Sustainable Cities
Author:
ISBN: 3038979457 3038979449 Year: 2019 Publisher: MDPI - Multidisciplinary Digital Publishing Institute

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The principle of sustainability should be strictly connected with safety, since both aim to conserve resources: in the case of sustainability, the resources are typically thought of as environmental, while in the case of safety, the resources are basically human. In spite of this common ground, discussions on sustainability usually give insufficient attention to safety. In the last years the EU has made large investments to increase the energy efficiency of the existing building stock, paving the way for a low-carbon future; however, less effort has been made to enhance its seismic resilience. Therefore, the safety and, consequently, the sustainability of towns situated in earthquake-prone countries remain inadequate. In such countries, energy renovation actions should be combined with seismic retrofitting. However, a number of barriers considerably limit the real possibility of extensively undertaking combined retrofit actions, especially for multi-owner housing and high-rise buildings. These barriers are of different kinds: technical (e.g., unfeasibility and/or ineffectiveness of conventional retrofit solutions), financial (e.g., high renovation costs, insufficient incentives/subsidies), organizational (e.g., occupants’ disruption and relocation, renovation consensus by condominium ownerships), and cultural/social (insufficient information and skills, lack of adequate policy measures for promoting renovation actions). This book aims to overcome these barriers and to bridge the gap between sustainability and safety, so to conserve both human and environmental resources.


Book
Oncologic Thermoradiotherapy: Need for Evidence, Harmonisation, and Innovation
Authors: --- ---
Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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The road of acceptance of oncologic thermotherapy/hyperthermia as a synergistic modality in combination with standard oncologic therapies is still bumpy. This is partially due to the lack of level I evidence from international, multicentric, randomized clinical trials including large patient numbers and a long term follow-up. Therefore we need more level I EVIDENCE from clinical trials, we need HARMONISATION and global acceptance for existing technologies and a common language understood by all stakeholders and we need INNOVATION in the fields of biology, clinics and technology to move thermotherapy/hyperthermia forward. This is the main focus of this reprint. In this reprintyou find carefully selected and peer-reviewed contributions from Africa, America, Asia, and Europe. The published papers from leading scientists from all over the world covering a broad range of timely research topics might also help to strengthen thermotherapy on a global level.

Keywords

Medicine --- Oncology --- perfusion estimation --- temperature monitoring --- conductivity reconstruction --- systems medicine --- immune system in silico --- perceptron --- antigen pattern --- danger signal --- fractionation --- immune response --- head and neck cancer --- hyperthermia --- reirradiation --- treatment outcome --- hyperthermia treatment planning --- adaptive planning --- temperature optimization --- low-middle-income group countries --- cancer --- radiotherapy --- chemotherapy --- recurrent breast cancers --- cervical cancer --- head and neck cancers --- cost-effective --- meta-analysis --- intensity-modulated radiotherapy --- prostate cancer --- thermal dose --- thermometric parameters --- preclinical data --- clinical evidence --- modulated electro-hyperthermia --- abscopal effect --- locally advanced cervical cancer --- resource-constrained setting --- radiosensitiser --- rectal cancer --- chemoradiotherapy --- tumour control --- loco-regional hyperthermia --- oncology --- cellular selection --- bioelectromagnetics --- complexity --- immune-effects --- moderate hyperthermia --- deep hyperthermia --- radiative hyperthermia --- patterns of care --- reimbursement --- regional hyperthermia --- neoadjuvant chemoradiation --- survival --- induced --- brachytherapy --- prostatic neoplasms --- interstitial hyperthermia --- treatment plan optimization --- prostate --- thermoradiotherapy --- linear quadratic model --- biological modeling --- thermal dosimetry --- hypoxia --- radiation therapy --- reoxygenation --- perfusion --- oxygen consumption rate --- local tumor control --- biomarker --- immune phenotype --- hyperthermia treatment sequence --- breast cancer --- immune checkpoint molecules --- dendritic cell activation --- n/a


Book
Oncologic Thermoradiotherapy: Need for Evidence, Harmonisation, and Innovation
Authors: --- ---
Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

The road of acceptance of oncologic thermotherapy/hyperthermia as a synergistic modality in combination with standard oncologic therapies is still bumpy. This is partially due to the lack of level I evidence from international, multicentric, randomized clinical trials including large patient numbers and a long term follow-up. Therefore we need more level I EVIDENCE from clinical trials, we need HARMONISATION and global acceptance for existing technologies and a common language understood by all stakeholders and we need INNOVATION in the fields of biology, clinics and technology to move thermotherapy/hyperthermia forward. This is the main focus of this reprint. In this reprintyou find carefully selected and peer-reviewed contributions from Africa, America, Asia, and Europe. The published papers from leading scientists from all over the world covering a broad range of timely research topics might also help to strengthen thermotherapy on a global level.

Keywords

Medicine --- Oncology --- perfusion estimation --- temperature monitoring --- conductivity reconstruction --- systems medicine --- immune system in silico --- perceptron --- antigen pattern --- danger signal --- fractionation --- immune response --- head and neck cancer --- hyperthermia --- reirradiation --- treatment outcome --- hyperthermia treatment planning --- adaptive planning --- temperature optimization --- low-middle-income group countries --- cancer --- radiotherapy --- chemotherapy --- recurrent breast cancers --- cervical cancer --- head and neck cancers --- cost-effective --- meta-analysis --- intensity-modulated radiotherapy --- prostate cancer --- thermal dose --- thermometric parameters --- preclinical data --- clinical evidence --- modulated electro-hyperthermia --- abscopal effect --- locally advanced cervical cancer --- resource-constrained setting --- radiosensitiser --- rectal cancer --- chemoradiotherapy --- tumour control --- loco-regional hyperthermia --- oncology --- cellular selection --- bioelectromagnetics --- complexity --- immune-effects --- moderate hyperthermia --- deep hyperthermia --- radiative hyperthermia --- patterns of care --- reimbursement --- regional hyperthermia --- neoadjuvant chemoradiation --- survival --- induced --- brachytherapy --- prostatic neoplasms --- interstitial hyperthermia --- treatment plan optimization --- prostate --- thermoradiotherapy --- linear quadratic model --- biological modeling --- thermal dosimetry --- hypoxia --- radiation therapy --- reoxygenation --- perfusion --- oxygen consumption rate --- local tumor control --- biomarker --- immune phenotype --- hyperthermia treatment sequence --- breast cancer --- immune checkpoint molecules --- dendritic cell activation --- n/a


Book
Oncologic Thermoradiotherapy: Need for Evidence, Harmonisation, and Innovation
Authors: --- ---
Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

Loading...
Export citation

Choose an application

Bookmark

Abstract

The road of acceptance of oncologic thermotherapy/hyperthermia as a synergistic modality in combination with standard oncologic therapies is still bumpy. This is partially due to the lack of level I evidence from international, multicentric, randomized clinical trials including large patient numbers and a long term follow-up. Therefore we need more level I EVIDENCE from clinical trials, we need HARMONISATION and global acceptance for existing technologies and a common language understood by all stakeholders and we need INNOVATION in the fields of biology, clinics and technology to move thermotherapy/hyperthermia forward. This is the main focus of this reprint. In this reprintyou find carefully selected and peer-reviewed contributions from Africa, America, Asia, and Europe. The published papers from leading scientists from all over the world covering a broad range of timely research topics might also help to strengthen thermotherapy on a global level.

Keywords

perfusion estimation --- temperature monitoring --- conductivity reconstruction --- systems medicine --- immune system in silico --- perceptron --- antigen pattern --- danger signal --- fractionation --- immune response --- head and neck cancer --- hyperthermia --- reirradiation --- treatment outcome --- hyperthermia treatment planning --- adaptive planning --- temperature optimization --- low-middle-income group countries --- cancer --- radiotherapy --- chemotherapy --- recurrent breast cancers --- cervical cancer --- head and neck cancers --- cost-effective --- meta-analysis --- intensity-modulated radiotherapy --- prostate cancer --- thermal dose --- thermometric parameters --- preclinical data --- clinical evidence --- modulated electro-hyperthermia --- abscopal effect --- locally advanced cervical cancer --- resource-constrained setting --- radiosensitiser --- rectal cancer --- chemoradiotherapy --- tumour control --- loco-regional hyperthermia --- oncology --- cellular selection --- bioelectromagnetics --- complexity --- immune-effects --- moderate hyperthermia --- deep hyperthermia --- radiative hyperthermia --- patterns of care --- reimbursement --- regional hyperthermia --- neoadjuvant chemoradiation --- survival --- induced --- brachytherapy --- prostatic neoplasms --- interstitial hyperthermia --- treatment plan optimization --- prostate --- thermoradiotherapy --- linear quadratic model --- biological modeling --- thermal dosimetry --- hypoxia --- radiation therapy --- reoxygenation --- perfusion --- oxygen consumption rate --- local tumor control --- biomarker --- immune phenotype --- hyperthermia treatment sequence --- breast cancer --- immune checkpoint molecules --- dendritic cell activation --- n/a

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