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Drugs --- Drug Screening --- Testing --- Methodology. --- methods.

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Drug Screening. --- Drugs --- Toxicology. --- Poisoning --- Médicaments --- Toxicologie --- Empoisonnement --- Drug Evaluation, Preclinical. --- Médicaments

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Toxicity testing --- Toxicity Tests --- Cells, Cultured --- Drug Screening --- Tissue Culture. --- In vitro. --- methods. --- drug effects. --- Tissue culture.

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Cancer --- Drug Evaluation --- Drug Screening --- Drug evaluation --- Drugs --- Interferon Type I --- Interferon --- Chemotherapy --- Evaluation --- Congresses. --- congresses. --- congresses. --- Congresses. --- Testing --- Congresses. --- congresses. --- Therapeutic use --- Congresses.

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This reference book contains a comprehensive selection of the most frequently used assays for reliably detecting pharmacological effects of potential drugs, including tests for cardiovascular, analgesic, psychotropic, metabolic, endocrine, respiratory, renal, and immunomodulatory activities. Each of the over 700 assays comprises a detailed protocol with the purpose and rationale of the method, a description of the experimental procedure, a critical assessment of the results and their pharmacological and clinical relevance, and pertinent references. Identification of specific tests is facilitated by the enclosed CD-ROM which allows for a quick and full text research. An appendix with guidelines and legal regulations for animal experiments in various countries will help to plan these experiments properly in accordance with the welfare of laboratory animals.

Biopharmaco-efficiency. Pharmacokinetics --- Pharmacosynthesis. Pharmacochemistry --- Drug Design --- Drug Screening --- Pharmacology, Experimental --- Pharmacologie expérimentale --- Pharmacologie expérimentale --- Drug Design. --- Drug Evaluation. --- Drug Evaluation, Preclinical. --- Pharmacology. --- Pharmacy. --- Biochemistry. --- Pharmacology/Toxicology. --- Biochemistry, general. --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemicals --- Chemotherapy --- Drugs --- Pharmacy --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medicine --- Materia medica --- Pharmacology --- Physiological effect --- Composition --- Testing. --- Clinical drug trials --- Clinical trials of drugs --- Drug bioscreening --- Drug trials --- Clinical pharmacology --- Drug development --- Clinical trials --- Effectiveness --- Testing --- Evaluation --- Drug evaluation --- Drug screening