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Thanks to their rich chemodiversity, marine natural products represent a unique source of new bioactive metabolites. As the new leading compounds in drug discovery and development, these molecules may represent challenges for the treatment of a number of human diseases, attracting the attention of many researchers during their chemical and biological studies. This Special Issue covers all fields of drugs research in which marine natural products are involved, including their isolation and characterization, biological activities, and medicinal applications as well as synthetic approaches and their related analogues. The cover picture shows “The Nudibranch mollusk Godiva quadricolor on a sponge, reflected under the surface during the low tide. Fusaro Lagoon, Bacoli (Naples)”.

Research & information: general --- Biology, life sciences --- Biochemistry --- alginate --- Sargassum duplicatum --- okra --- antioxidant --- diabetic --- wound healing --- sulfavant --- sulfoquinovosyldiacylglycerols --- sulfoglycolipids --- mass spectrometry --- UHPLC-MS --- lipids --- cancer therapy --- gold nanoparticles --- marine products --- natural products --- photosensitizer --- purpurin 18 --- reactive oxygen species --- seaweed --- biosilica --- diatom frustule --- sustainable production --- drug delivery --- Sargassum ilicifolium --- mangosteen rind --- diabetic mice --- Aquimarina sp. --- diketopiperazine --- N-phenethylacetamide --- epithelial-mesenchymal transition (EMT) --- A549 cells --- n/a

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• Reference Manager
• EndNote
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Thanks to their rich chemodiversity, marine natural products represent a unique source of new bioactive metabolites. As the new leading compounds in drug discovery and development, these molecules may represent challenges for the treatment of a number of human diseases, attracting the attention of many researchers during their chemical and biological studies. This Special Issue covers all fields of drugs research in which marine natural products are involved, including their isolation and characterization, biological activities, and medicinal applications as well as synthetic approaches and their related analogues. The cover picture shows “The Nudibranch mollusk Godiva quadricolor on a sponge, reflected under the surface during the low tide. Fusaro Lagoon, Bacoli (Naples)”.

Research & information: general --- Biology, life sciences --- Biochemistry --- alginate --- Sargassum duplicatum --- okra --- antioxidant --- diabetic --- wound healing --- sulfavant --- sulfoquinovosyldiacylglycerols --- sulfoglycolipids --- mass spectrometry --- UHPLC-MS --- lipids --- cancer therapy --- gold nanoparticles --- marine products --- natural products --- photosensitizer --- purpurin 18 --- reactive oxygen species --- seaweed --- biosilica --- diatom frustule --- sustainable production --- drug delivery --- Sargassum ilicifolium --- mangosteen rind --- diabetic mice --- Aquimarina sp. --- diketopiperazine --- N-phenethylacetamide --- epithelial-mesenchymal transition (EMT) --- A549 cells --- alginate --- Sargassum duplicatum --- okra --- antioxidant --- diabetic --- wound healing --- sulfavant --- sulfoquinovosyldiacylglycerols --- sulfoglycolipids --- mass spectrometry --- UHPLC-MS --- lipids --- cancer therapy --- gold nanoparticles --- marine products --- natural products --- photosensitizer --- purpurin 18 --- reactive oxygen species --- seaweed --- biosilica --- diatom frustule --- sustainable production --- drug delivery --- Sargassum ilicifolium --- mangosteen rind --- diabetic mice --- Aquimarina sp. --- diketopiperazine --- N-phenethylacetamide --- epithelial-mesenchymal transition (EMT) --- A549 cells

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This reprint contains original research and review articles describing recent advances in our understanding of the transcriptional regulation of cardiac development and disease mechanisms. All articles were originally published in the International Journal of Molecular Sciences (IJMS).

Research & information: general --- Biology, life sciences --- Biochemistry --- pluripotent stem cells --- cardiomyocytes --- cardiac tissue engineering --- human heart --- tissue maturation --- Wilms' tumor suppressor 1 --- cardiomyocyte differentiation --- mouse embryonic stem cells --- myocardial infarction --- YAP --- TEAD1 --- Toll-like receptor --- heart --- TLR4 --- cardiomyocyte --- innate immune responses --- Wilms' tumor suppressor 1 (Wt1) --- cardiac development --- coronary vessel formation --- transcriptional regulation --- cardiac malformation --- epicardium --- epicardial derived cells (EPDCs) --- epithelial mesenchymal transition (EMT) --- cardiac cell fate --- regeneration --- arrhythmogenic cardiomyopathy (ACM) --- lamin A/C --- atomic force microscopy (AFM) --- cell-cell adhesion --- neonatal rat ventricular fibroblasts (NRVF) --- tunneling nanotubes (TNT) --- gene therapy --- cardiovascular diseases --- cardiac regeneration --- cardiac reprogramming --- therapeutic angiogenesis --- growth factors --- reactive oxygen species --- apoptosis --- Bmp signaling --- Hand1 --- Smad --- heart development --- SH3BGR --- cardiac hypertrophy --- SRF signaling --- Hippo signaling --- cardiomyogenic differentiation --- cardiac mesenchymal stromal cell --- hydrogels --- histone deacetylase inhibitors --- translational studies --- gene expression and regulation --- cardiomyopathy --- heart failure --- reverse remodelling --- left ventricular assist device --- pluripotent stem cells --- cardiomyocytes --- cardiac tissue engineering --- human heart --- tissue maturation --- Wilms' tumor suppressor 1 --- cardiomyocyte differentiation --- mouse embryonic stem cells --- myocardial infarction --- YAP --- TEAD1 --- Toll-like receptor --- heart --- TLR4 --- cardiomyocyte --- innate immune responses --- Wilms' tumor suppressor 1 (Wt1) --- cardiac development --- coronary vessel formation --- transcriptional regulation --- cardiac malformation --- epicardium --- epicardial derived cells (EPDCs) --- epithelial mesenchymal transition (EMT) --- cardiac cell fate --- regeneration --- arrhythmogenic cardiomyopathy (ACM) --- lamin A/C --- atomic force microscopy (AFM) --- cell-cell adhesion --- neonatal rat ventricular fibroblasts (NRVF) --- tunneling nanotubes (TNT) --- gene therapy --- cardiovascular diseases --- cardiac regeneration --- cardiac reprogramming --- therapeutic angiogenesis --- growth factors --- reactive oxygen species --- apoptosis --- Bmp signaling --- Hand1 --- Smad --- heart development --- SH3BGR --- cardiac hypertrophy --- SRF signaling --- Hippo signaling --- cardiomyogenic differentiation --- cardiac mesenchymal stromal cell --- hydrogels --- histone deacetylase inhibitors --- translational studies --- gene expression and regulation --- cardiomyopathy --- heart failure --- reverse remodelling --- left ventricular assist device