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CATTLE --- GENETICS --- CATTLE DISEASES --- GENETICS --- GENETIC PHENOMENA --- CHROMOSOME MAPPING --- LINKAGE DISEQUILIBRIUM --- QUANTITATIVE TRAIT, HERITABLE
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Cattle --- genetics --- Genome --- Quantitative trait loci --- Chromosome mapping --- X chromosome --- Linkage disequilibrium --- Phenotype
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As researchers continue to make enormous progress in mapping disease genes, exciting, novel, and complex analyses have emerged. In Linkage Disequilibrium and Association Mapping: Analysis and Applications, scientists from around the world, who are leaders in this field, contribute their vast experience and expertise to produce a comprehensive and fascinating text for researchers and clinicians alike. The volume comprises four general sections: the first presents an overview and historical basis of the subject. The second section considers the developing methodology and recent findings from studies which have characterized the genome-wide linkage disequilibrium structure in enormous detail. The following section examines all aspects of disease association mapping methodology, and the final two chapters review the early successes in mapping genes involved in two of the most important human diseases: asthma and type 2 diabetes.
Linkage Disequilibrium. --- Chromosome Mapping. --- Genomics --- Gene mapping. --- Génomique --- Cartes chromosomiques --- Statistical methods. --- Méthodes statistiques --- Gene mapping --- Linkage Disequilibrium --- Chromosome Mapping --- Statistical methods --- Electronic books. -- local. --- Genomics -- Statistical methods. --- Genetic Techniques --- Genetic Linkage --- Investigative Techniques --- Genetic Phenomena --- Phenomena and Processes --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Genetics --- Biology --- Health & Biological Sciences --- Chromosome mapping --- Genetic mapping --- Genome mapping --- Linkage mapping (Genetics) --- Mapping, Gene --- Genome research --- Genomes --- Research --- Molecular genetics --- Technique --- Human genetics. --- Cytology. --- Human Genetics. --- Cell Biology. --- Cell biology --- Cellular biology --- Cells --- Cytologists --- Heredity, Human --- Human biology --- Physical anthropology --- Genomics - Statistical methods
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To show the importance of stochastic processes in the change of gene frequencies, the authors discuss topics ranging from molecular evolution to two-locus problems in terms of diffusion models. Throughout their discussion, they come to grips with one of the most challenging problems in population genetics--the ways in which genetic variability is maintained in Mendelian populations.R.A. Fisher, J.B.S. Haldane, and Sewall Wright, in pioneering works, confirmed the usefulness of mathematical theory in population genetics. The synthesis their work achieved is recognized today as mathematical genetics, that branch of genetics whose aim is to investigate the laws governing the genetic structure of natural populations and, consequently, to clarify the mechanisms of evolution.For the benefit of population geneticists without advanced mathematical training, Professors Kimura and Ohta use verbal description rather than mathematical symbolism wherever practicable. A mathematical appendix is included.
Population genetics --- Mathematical models. --- F-statistics. --- G-C content. --- K distribution. --- Malthusian parameter. --- Ordovician. --- adaptive surface. --- apparent. --- breeding structure. --- chromosomal variation. --- darwin. --- evolutionary rates. --- fossils, living. --- insulins. --- lethal equivalent. --- linkage disequilibrium. --- mutation, advantageous. --- natural selection. --- quasi-equilibrium surface. --- rate of. --- selection. --- selective values. --- steady flux equation. --- viability polygenes.
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Traditionally a scientific theory is viewed as based on universal laws of nature that serve as axioms for logical deduction. In analyzing the logical structure of evolutionary biology, Elisabeth Lloyd argues that the semantic account is more appropriate and powerful. This book will be of interest to biologists and philosophers alike.
Population genetics --- Evolution (Biology) --- Philosophy. --- Adaptation. --- Additivity definition. --- Aggregate properties. --- Altruism. --- Axiomatization. --- Beckner, Morton. --- Brandon, Robert. --- Buss, Leo. --- Causes. --- Colonization. --- Contextual analysis. --- Covering-law view. --- Darwin, Charles. --- Deterministic models. --- Effect hypothesis. --- Emergent properties. --- Environment. --- Experimental design. --- Family-structured models. --- Fertility selection. --- Fitness. --- Futuyma, Douglas. --- Game theory. --- Gametic selection. --- Genic fitnesses. --- Group effect. --- Haystack model. --- Heterozygote superiority. --- Hymenoptera. --- Independent assortment. --- Interrelation of models. --- Island biogeography. --- Isomorphism. --- Kimura, Motoo. --- Laws. --- Levels of selection. --- Linkage disequilibrium. --- Logical positivism. --- Macroevolution. --- Mangrove islands. --- Model type. --- Modifier genes. --- Mutation. --- Natural selection. --- Optimization models. --- Organelle selection. --- Organismic selection. --- Parameters. --- Phytoplankton. --- Population size. --- Random mating. --- Realism.
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To meet the global food demand of an increasing population, food production has to be increased by 60% by 2050. The main production constraints, such as climate change, biotic stresses, abiotic stresses, soil nutrition deficiency problems, problematic soils, etc., have to be addressed on an urgent basis. More than 50% of human calories are from three major cereals: rice, wheat, and maize. The harnessing of genetic diversity by novel allele mining assisted by recent advances in biotechnological and bioinformatics tools will enhance the utilization of the hidden treasures in the gene bank. Technological advances in plant breeding will provide some solutions for the biofortification, stress resistance, yield potential, and quality improvement in staple crops. The elucidation of the genetic, physiological, and molecular basis of useful traits and the improvement of the improved donors containing multiple traits are key activities for variety development. High-throughput genotyping systems assisted by bioinformatics and data science provide efficient and easy tools for geneticists and breeders. Recently, new breeding techniques applied in some food crops have become game-changers in the global food crop market. With this background, we invited 18 eminent researchers working on food crops from across the world to contribute their high-quality original research manuscripts. The research studies covered modern food crop genetics and breeding.
Research & information: general --- Biology, life sciences --- Technology, engineering, agriculture --- dry direct-seeded rice --- early vigor --- QTL --- candidate gene --- phenotyping --- EMS --- MutMap --- mutagenesis --- CLE7 --- tropical maize --- fasciation --- mapping --- radish --- microspore culture --- regeneration rate --- outcrossing --- two-way pseudo-testcross model --- Oryza sativa L. --- PPDK --- flo4-5 --- floury endosperm --- rice --- allelopathy --- yield --- HYV --- Tongil --- indica --- japonica --- SNP --- molecular breeding --- wheat quality --- wheat milling --- wheat hardness --- puroindolines --- water absorption capacity --- crop genetics --- Solanum tuberosum --- abiotic stress --- phenylpropanoids --- essential amino acid --- transcriptome --- small RNA --- comparative genomics --- nutrition --- days to heading --- Hd1 --- Ghd7 --- Hd16 --- chromosome segment substitution lines (CSSLs) --- quantitative trait locus (QTL) --- marker-assisted selection (MAS) --- cold tolerance (CT) --- gene editing --- genetically modified --- genetically modified organism (GMO) --- crop breeding --- ribonucleoprotein complex (RNP) --- genetic screening --- landraces --- genetic diversity --- population structure --- West Africa --- maize improvement --- DArTseq markers --- co-expression network --- drought-tolerant-yield --- reproductive-stage drought --- qDTYs --- transcriptomics --- watermelon --- pentatricopeptide-repeat (PPR) gene family --- comprehensive analysis --- expression profiling --- flesh color --- canola --- Brassica napus --- genetics --- gene technology --- genomics --- disease resistance --- CSSLs --- drought stress --- ‘KDML105’ rice --- low-temperature germinability --- interspecific cross --- interaction --- peanut --- core collection --- genome-wide association study --- linkage disequilibrium
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Since the 1980s, agriculture and plant breeding have changed with the development of molecular marker technology. In recent decades, different types of molecular markers have been used for different purposes: mapping, marker-assisted selection, characterization of genetic resources, etc. These have produced effective genotyping, but the results have been costly and time-consuming due to the small number of markers that could be tested simultaneously. Recent advances in molecular marker technologies such as the development of high-throughput genotyping platforms, genotyping by sequencing, and the release of the genome sequences of major crop plants have opened new possibilities for advancing crop improvement. This Special Issue collects 16 research studies, including the application of molecular markers in 11 crop species, from the generation of linkage maps and diversity studies to the application of marker-assisted selection and genomic prediction.
Research & information: general --- Biology, life sciences --- durum wheat --- landraces --- marker-trait association --- root system architecture --- sugarcane --- parental line --- population structure --- plant breeding --- genetic diversity --- simple sequence repeats (SSR) --- Persea americana --- SMRT sequencing --- simple sequence repeat --- genetic relationship --- flavonoid biosynthesis --- fruit coloration --- marker-assisted selection --- microsatellites --- Rubus --- gene prioritization --- linkage disequilibrium --- tropical maize --- brown rice recovery --- milled rice recovery --- head rice recovery --- milling yield traits --- QTL mapping --- rice (Oryza sativa L.) --- tetraploid potato --- SNP markers --- SLAF-seq technology --- high-density genetic linkage map --- genome wide association study --- GWAS water use --- agronomic traits --- MTAs --- candidate genes --- TKW --- sedimentation volume --- SDS --- YR --- drought stress --- association mapping --- QTL hotspot --- seminal root --- gene pyramiding --- aroma --- QTL --- chromosome --- selection --- introgression line --- maize (Zea mays L.) --- Striga resistance/tolerance --- F2:3 biparental mapping --- Marker-assisted selection --- persimmon --- sex determination --- fruit astringency --- molecular markers --- genomics --- genomic selection --- genomic prediction --- whole genome regression --- grain quality --- near infra-red spectroscopy --- cereal crop --- sorghum --- multi-trait --- Triticum aestivum --- mapping population --- leaf rust --- stem rust --- pathogen races --- disease resistance --- apricot --- MAS --- breeding --- MATH --- PPV resistance --- agarose --- ParPMC --- ParPMC2-del --- high resolution melting --- ISBP markers --- drought --- MQTL --- wheat variability --- crop breeding --- genetic maps --- GWAS --- marker assisted selection --- DNA sequencing
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To meet the global food demand of an increasing population, food production has to be increased by 60% by 2050. The main production constraints, such as climate change, biotic stresses, abiotic stresses, soil nutrition deficiency problems, problematic soils, etc., have to be addressed on an urgent basis. More than 50% of human calories are from three major cereals: rice, wheat, and maize. The harnessing of genetic diversity by novel allele mining assisted by recent advances in biotechnological and bioinformatics tools will enhance the utilization of the hidden treasures in the gene bank. Technological advances in plant breeding will provide some solutions for the biofortification, stress resistance, yield potential, and quality improvement in staple crops. The elucidation of the genetic, physiological, and molecular basis of useful traits and the improvement of the improved donors containing multiple traits are key activities for variety development. High-throughput genotyping systems assisted by bioinformatics and data science provide efficient and easy tools for geneticists and breeders. Recently, new breeding techniques applied in some food crops have become game-changers in the global food crop market. With this background, we invited 18 eminent researchers working on food crops from across the world to contribute their high-quality original research manuscripts. The research studies covered modern food crop genetics and breeding.
Research & information: general --- Biology, life sciences --- Technology, engineering, agriculture --- dry direct-seeded rice --- early vigor --- QTL --- candidate gene --- phenotyping --- EMS --- MutMap --- mutagenesis --- CLE7 --- tropical maize --- fasciation --- mapping --- radish --- microspore culture --- regeneration rate --- outcrossing --- two-way pseudo-testcross model --- Oryza sativa L. --- PPDK --- flo4-5 --- floury endosperm --- rice --- allelopathy --- yield --- HYV --- Tongil --- indica --- japonica --- SNP --- molecular breeding --- wheat quality --- wheat milling --- wheat hardness --- puroindolines --- water absorption capacity --- crop genetics --- Solanum tuberosum --- abiotic stress --- phenylpropanoids --- essential amino acid --- transcriptome --- small RNA --- comparative genomics --- nutrition --- days to heading --- Hd1 --- Ghd7 --- Hd16 --- chromosome segment substitution lines (CSSLs) --- quantitative trait locus (QTL) --- marker-assisted selection (MAS) --- cold tolerance (CT) --- gene editing --- genetically modified --- genetically modified organism (GMO) --- crop breeding --- ribonucleoprotein complex (RNP) --- genetic screening --- landraces --- genetic diversity --- population structure --- West Africa --- maize improvement --- DArTseq markers --- co-expression network --- drought-tolerant-yield --- reproductive-stage drought --- qDTYs --- transcriptomics --- watermelon --- pentatricopeptide-repeat (PPR) gene family --- comprehensive analysis --- expression profiling --- flesh color --- canola --- Brassica napus --- genetics --- gene technology --- genomics --- disease resistance --- CSSLs --- drought stress --- ‘KDML105’ rice --- low-temperature germinability --- interspecific cross --- interaction --- peanut --- core collection --- genome-wide association study --- linkage disequilibrium
Choose an application
Since the 1980s, agriculture and plant breeding have changed with the development of molecular marker technology. In recent decades, different types of molecular markers have been used for different purposes: mapping, marker-assisted selection, characterization of genetic resources, etc. These have produced effective genotyping, but the results have been costly and time-consuming due to the small number of markers that could be tested simultaneously. Recent advances in molecular marker technologies such as the development of high-throughput genotyping platforms, genotyping by sequencing, and the release of the genome sequences of major crop plants have opened new possibilities for advancing crop improvement. This Special Issue collects 16 research studies, including the application of molecular markers in 11 crop species, from the generation of linkage maps and diversity studies to the application of marker-assisted selection and genomic prediction.
Research & information: general --- Biology, life sciences --- durum wheat --- landraces --- marker-trait association --- root system architecture --- sugarcane --- parental line --- population structure --- plant breeding --- genetic diversity --- simple sequence repeats (SSR) --- Persea americana --- SMRT sequencing --- simple sequence repeat --- genetic relationship --- flavonoid biosynthesis --- fruit coloration --- marker-assisted selection --- microsatellites --- Rubus --- gene prioritization --- linkage disequilibrium --- tropical maize --- brown rice recovery --- milled rice recovery --- head rice recovery --- milling yield traits --- QTL mapping --- rice (Oryza sativa L.) --- tetraploid potato --- SNP markers --- SLAF-seq technology --- high-density genetic linkage map --- genome wide association study --- GWAS water use --- agronomic traits --- MTAs --- candidate genes --- TKW --- sedimentation volume --- SDS --- YR --- drought stress --- association mapping --- QTL hotspot --- seminal root --- gene pyramiding --- aroma --- QTL --- chromosome --- selection --- introgression line --- maize (Zea mays L.) --- Striga resistance/tolerance --- F2:3 biparental mapping --- Marker-assisted selection --- persimmon --- sex determination --- fruit astringency --- molecular markers --- genomics --- genomic selection --- genomic prediction --- whole genome regression --- grain quality --- near infra-red spectroscopy --- cereal crop --- sorghum --- multi-trait --- Triticum aestivum --- mapping population --- leaf rust --- stem rust --- pathogen races --- disease resistance --- apricot --- MAS --- breeding --- MATH --- PPV resistance --- agarose --- ParPMC --- ParPMC2-del --- high resolution melting --- ISBP markers --- drought --- MQTL --- wheat variability --- crop breeding --- genetic maps --- GWAS --- marker assisted selection --- DNA sequencing
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The origin of species has fascinated both biologists and the general public since the publication of Darwin's Origin of Species in 1859. Significant progress in understanding the process was achieved in the "modern synthesis," when Theodosius Dobzhansky, Ernst Mayr, and others reconciled Mendelian genetics with Darwin's natural selection. Although evolutionary biologists have developed significant new theory and data about speciation in the years since the modern synthesis, this book represents the first systematic attempt to summarize and generalize what mathematical models tell us about the dynamics of speciation. Fitness Landscapes and the Origin of Species presents both an overview of the forty years of previous theoretical research and the author's new results. Sergey Gavrilets uses a unified framework based on the notion of fitness landscapes introduced by Sewall Wright in 1932, generalizing this notion to explore the consequences of the huge dimensionality of fitness landscapes that correspond to biological systems. In contrast to previous theoretical work, which was based largely on numerical simulations, Gavrilets develops simple mathematical models that allow for analytical investigation and clear interpretation in biological terms. Covering controversial topics, including sympatric speciation and the effects of sexual conflict on speciation, this book builds for the first time a general, quantitative theory for the origin of species.
Models, Genetic. --- Population Genetics. --- Evolution. --- Population biology. --- Species diversity. --- Population genetics --- Evolution (Biology) --- Species --- Mathematical models. --- Adaptive radiation. --- Allele frequency. --- Allele. --- Allopatric speciation. --- Assortative mating. --- Biodiversity. --- Character displacement. --- Charles Darwin. --- Digamma function. --- Directional selection. --- Disruptive selection. --- Ecological niche. --- Ecological selection. --- Ecology. --- Ecotype. --- Error threshold (evolution). --- Evolution of dominance. --- Evolutionary biology. --- Evolutionary dynamics. --- Evolutionary ecology. --- Evolutionary radiation. --- Fisher's fundamental theorem of natural selection. --- Fisherian runaway. --- Fitness (biology). --- Fitness function. --- Fitness landscape. --- Fitness model (network theory). --- Founder effect. --- Frequency-dependent selection. --- G-test. --- Gene flow. --- Gene. --- Genetic architecture. --- Genetic association. --- Genetic correlation. --- Genetic distance. --- Genetic divergence. --- Genetic drift. --- Genetic heterogeneity. --- Genetic structure. --- Genetic variability. --- Genetic variance. --- Genetic variation. --- Genetics and the Origin of Species. --- Genotype frequency. --- Genotype-phenotype distinction. --- Genotype. --- Group selection. --- Haldane's rule. --- Haplotype. --- Hardy–Weinberg principle. --- Hybrid (biology). --- Hybrid speciation. --- Hybrid zone. --- Inbreeding. --- Linkage disequilibrium. --- Local adaptation. --- Logarithm. --- Macroevolution. --- Mate choice. --- Mating preferences. --- Mating. --- Model organism. --- Modern evolutionary synthesis. --- Mutation rate. --- Mutation–selection balance. --- Natural selection. --- Nearly neutral theory of molecular evolution. --- Neutral network (evolution). --- On the Origin of Species. --- Order statistic. --- Parapatric speciation. --- Peripatric speciation. --- Phenotype. --- Phenotypic trait. --- Polymorphism (biology). --- Population ecology. --- Population genetics. --- Population size. --- Probability. --- Quantitative genetics. --- Quantitative trait locus. --- Rate of evolution. --- Reproductive isolation. --- Reproductive success. --- Ring species. --- Segregate (taxonomy). --- Selection coefficient. --- Sexual selection. --- Spatial ecology. --- Speciation (genetic algorithm). --- Speciation. --- Species complex. --- Species–area curve. --- Stepwise mutation model. --- Sympatric speciation. --- Taxonomy (biology). --- Trait theory.
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