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This innovative, introductory text is authored by key subject leaders in clinical neuroendocrinology with decades of research and teaching experience. Addressing the need for a concise description of human neuroendocrine systems, this important review of various significant basic science advances is relevant for all levels of experience. An indispensable resource for a variety of learners, this book will also enable biomedical science graduate students to extend their knowledge using its valuable clinical context. Beautifully illustrated, this text integrates basic scientific principles with clinical cases and includes several illustrated imaging studies, and in-depth discussions of basic principles and their interpretations. Extensive reference lists of clinical papers, teaching resources and a selection of review questions are included with each chapter, emphasizing the real-life importance of basic neuroendocrine principles in human health and disease. Clinical reviews are included to provide convenient links to more specialized texts, ensuring a successful springboard for learners worldwide.
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This book is designed as an introductory text in neuroendocrinology; the study of the interaction between the brain and endocrine system and the influence of this on behaviour. The endocrine glands, pituitary gland and hypothalamus and their interactions and hormones are discussed. The action of steroid and thyroid hormone receptors and the regulation of target cell response to hormones is examined. The function of neuropeptides is discussed with respect to the neuroendocrine system and behaviour. The neuroimmune system and lymphokines are described and the interaction between the neuroendocrine and neuroimmune systems discussed. Finally, methods for studying hormonal influences on behaviour are outlined. Each chapter has review and essay questions designed for advanced students and honours or graduate students with a background in neuroscience, respectively.
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How does the brain regulate sexual behavior, or control our body weight? How do we cope with stress? Addressing these questions and many more besides, this thoroughly revised new edition reflects the significant advances that have been made in the study of neuroendocrinology over the last twenty years. The text examines the importance of the hypothalamus in regulating hormone secretion from the endocrine glands, describing novel sites of hormone release including bone, heart, skeletal muscle and liver. The role of steroid hormone, neurotransmitter and peptide receptors, and the molecular responses of target tissues, is integrated into the discussion of the neuroendocrine brain, especially through changes in gene expression. Particular attention is attached to neuropeptides, including their profound influence on behavior. Complete with new full-color figures throughout, along with review and essay questions for each chapter, this is an ideal resource for undergraduate and graduate students of neuroscience, psychology, biology and physiology.
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