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Quatrième de couverture : "La thérapie photodynamique (TPD) est une méthode de traitement des cancers localisés, basée sur une réaction photochimique entre une molécule activée par la lumière ou photosensibilisateur (PS), la lumière et l'oxygène moléculaire. Le choix correct du PS est d'une importance fondamentale pour l'efficacité de la TPD. Malgré de nombreuses études dans ce domaine, la plupart des PS connus présentent certains inconvénients, par exemple le manque de spécificité et d'agrégation en milieu aqueux. Par conséquent, la recherche d'une PS idéale est essentielle pour le développement ultérieur de la TPD. Nous passons ici en revue la classification et analysons les principales caractéristiques de différentes générations de PS et décrivent les mécanismes de leur action. Différentes méthodes d'administration ciblée de PS aux cellules tumorales sont examinées. Les avantages des nanoparticules de PS avec l'effet d'émission induite par agrégation (AIE) par rapport aux photosensibilisateurs classiques sont présentés. L'intelligence artificielle a été utilisée pour traduire ce livre."

Nanoparticles --- Nanotechnology --- Theranostic Nanomedicine --- Biomedical Engineering

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Nanostructures. --- Nanoscience --- Physics --- Theranostic Nanomedicine. --- Nanomaterials --- Nanostructured Materials --- Material, Nanostructured --- Materials, Nanostructured --- Nanomaterial --- Nanostructure --- Nanostructured Material --- Nanotechnology --- Molecular Imprinting --- Photothermal Theranostics --- Nanomedicine, Theranostic --- Nanomedicines, Theranostic --- Photothermal Theranostic --- Theranostic Nanomedicines

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Functionalized Carbon Nanomaterials for Theranostic Applications offers insights into the developments and trends that are progressing fast in the field of functionalized carbon nanomaterials-based devices as diagnostic tools for early stage detection of human diseases. The book provides information on how functionalized carbon nanomaterials are being used as the basis for products, such as early disease diagnostic kits, quantum dots for medical imaging and a growing list of other applications. Sections cover different mechanical, absorption, optical and electrical properties than those found in original nanomaterials. This is an important reference source that will be valuable to materials scientists, biomedical engineers and pharmaceutical scientists who are looking to increase their understanding on how functionalized carbon nanomaterials are being used for a variety of theranostic applications.

Nanostructured materials. --- Biomedical materials. --- Nanomedicine. --- Nanotechnology --- Nanomedicine --- Nanostructures --- Theranostic Nanomedicine --- Health aspects.

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The ability to genetically engineer oncolytic viruses in order to minimize side effects and improve the selective targeting of tumor cells has opened up novel opportunities for treating cancer. Understanding the mechanisms involved and the complex interaction between the viruses and the immune system will undoubtedly help guide the development of new strategies. Theranostic biomarkers to monitor these therapies in clinical trials serve an important need in this innovative field and demand further research.

theranostic nanomedicine --- cancer immunotherapy --- oncolytic viruses --- antitumor immunity --- oncoimmunology --- gene expression --- transgenes

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The aim of this Research Topic was to assemble a series of articles describing basic, preclinical and clinical research studies on radiopharmaceuticals and nuclear medicine. The articles were written by attendees of the third Nuclear Technologies for Health Symposium (NTHS, 10th-11th March 2015, Nantes, Frances) under the auspices of the IRON LabEx (Innovative Radiopharmaceuticals for Oncology and Neurology Laboratory of Excellence). This French network, gathering approximately 160 scientists from 12 academic research teams (Funded by “investissements d’Avenir”), fosters transdisciplinary projects between teams with expertise in chemistry, radiochemistry, radiopharmacy, formulation, biology, nuclear medicine and medical physics. The 12 articles within this resulting eBook present a series of comprehensive reviews and original research papers on multimodality imaging and targeted radionuclide therapy; illustrating the different facets of studies currently conducted in these domains.

multimodality imaging --- PET imaging --- targeted radionuclide therapy --- Radiopharmaceuticals --- theranostic --- Pretargeted radioimmunotherapy --- personalized medicine