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A full awareness of the role played by a healthy diet, as part of a healthy lifestyle, in countering or slowing-down chronic and degenerative diseases has strongly increased the interest in food bioactives and the return of ancient foods that are nowadays considered functional. In fact, these dietary substances, to which nutraceutical attributes are increasingly entrusted, could display disease-preventing effects on animals and humans. In this context, polyphenols, which are widespread and mostly copious in dietary plant sources, have gained a lot of attention thanks to their potential ability to halt or reverse oxidative stress-related diseases. Indeed, food could contain, beyond health-promoting compounds, toxicants which are naturally occurring or process-induced dietary compounds with adverse effects on human health. The presence and abundance of bioactives are strictly related to their food source. Edible plant components largely contain beneficial secondary metabolites, but understanding them fully is still an important challenge as complex biotic and abiotic interactions are involved in their biosynthesis. Analytical methods, which are increasingly powerful, could enhance our knowledge of food bioactives, whereas the deep investigation of their bioactivity and bioavailability could make them particularly useful.

Medicine --- Urtica dioica --- natural products bioactivity --- food bioactives --- nutraceuticals --- cancer therapy --- breast cancer --- Aloe vera --- Aloe vera polysaccharides --- in vitro fermentation --- SCFAs --- antioxidant capacity --- food waste recovery --- grape leaves --- UHPLC-HR-MS/MS analysis --- flavonol glycuronides recovery --- linoleic acid peroxidation products --- hexane --- gastric cells --- metabolomics --- cDNA microarray --- avocado --- LC/MS --- fat-soluble vitamins --- carotenoids --- Cannabis sativa L. --- phenylamides --- lignanamides --- hemp seeds --- high resolution tandem mass spectrometry --- U-87 glioblastoma cells --- cytotoxicity --- Pistacia vera --- antioxidant --- quality --- tocopherol --- FTIR --- discriminant analysis --- pistacia (Pistacia vera) hulls --- anticancer --- bacterial resistance --- efflux pumps --- terpenoids --- thymol --- carvacrol --- Rosmarinus officinalis L. --- fresh young shoots tincture --- polyphenols --- terpenes --- hepatoprotective --- n/a

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A full awareness of the role played by a healthy diet, as part of a healthy lifestyle, in countering or slowing-down chronic and degenerative diseases has strongly increased the interest in food bioactives and the return of ancient foods that are nowadays considered functional. In fact, these dietary substances, to which nutraceutical attributes are increasingly entrusted, could display disease-preventing effects on animals and humans. In this context, polyphenols, which are widespread and mostly copious in dietary plant sources, have gained a lot of attention thanks to their potential ability to halt or reverse oxidative stress-related diseases. Indeed, food could contain, beyond health-promoting compounds, toxicants which are naturally occurring or process-induced dietary compounds with adverse effects on human health. The presence and abundance of bioactives are strictly related to their food source. Edible plant components largely contain beneficial secondary metabolites, but understanding them fully is still an important challenge as complex biotic and abiotic interactions are involved in their biosynthesis. Analytical methods, which are increasingly powerful, could enhance our knowledge of food bioactives, whereas the deep investigation of their bioactivity and bioavailability could make them particularly useful.

Urtica dioica --- natural products bioactivity --- food bioactives --- nutraceuticals --- cancer therapy --- breast cancer --- Aloe vera --- Aloe vera polysaccharides --- in vitro fermentation --- SCFAs --- antioxidant capacity --- food waste recovery --- grape leaves --- UHPLC-HR-MS/MS analysis --- flavonol glycuronides recovery --- linoleic acid peroxidation products --- hexane --- gastric cells --- metabolomics --- cDNA microarray --- avocado --- LC/MS --- fat-soluble vitamins --- carotenoids --- Cannabis sativa L. --- phenylamides --- lignanamides --- hemp seeds --- high resolution tandem mass spectrometry --- U-87 glioblastoma cells --- cytotoxicity --- Pistacia vera --- antioxidant --- quality --- tocopherol --- FTIR --- discriminant analysis --- pistacia (Pistacia vera) hulls --- anticancer --- bacterial resistance --- efflux pumps --- terpenoids --- thymol --- carvacrol --- Rosmarinus officinalis L. --- fresh young shoots tincture --- polyphenols --- terpenes --- hepatoprotective --- n/a

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A study of the analogies between alchemy, Christian dogma, and psychological symbolism. Revised translation, with new bibliography and index.

Psychoanalysis. --- Psychology --- Religious aspects. --- Albertus Magnus. --- Alchemical symbol. --- Alchemy. --- All things. --- Allegory. --- Allusion. --- Analogy. --- Analytical psychology. --- Anima mundi. --- Antinomy. --- Antithesis. --- Archetype. --- Astrology. --- Aurora consurgens. --- Author. --- Axiom. --- Bibliography. --- Buddhism. --- Christian apologetics. --- Christianity. --- Church Fathers. --- Classical element. --- Concept. --- Conscience. --- Consciousness. --- Deity. --- Demiurge. --- Edition (book). --- Emblem. --- Exaltation (astrology). --- Explanation. --- Filius philosophorum. --- Geber. --- Gnosticism. --- God the Father. --- God-man (Christianity). --- God. --- Good and evil. --- Heimarmene. --- Hermaphroditus. --- Hermes Trismegistus. --- Hermetica. --- Hermeticism. --- Ibid (short story). --- Illustration. --- Individuation. --- Instance (computer science). --- Invisibility. --- Lecture. --- Leprosy. --- Literature. --- Michael Maier. --- Mrs. --- Musaeum Hermeticum. --- Mutus Liber. --- Natural science. --- Nekyia. --- Nigredo. --- Nous. --- Ouroboros. --- Paganism. --- Paracelsus. --- Phenomenon. --- Philosopher. --- Philosophy. --- Physis. --- Prima materia. --- Probabilism. --- Professor. --- Pseudo-Aristotle. --- Psyche (psychology). --- Psychological Types. --- Psychology of the Unconscious. --- Psychology. --- Qilin. --- Reality. --- Rebis. --- Religion. --- Rite. --- Soul and Body. --- Spirituality. --- Splendor Solis. --- Summum bonum. --- Symptom. --- Tertullian. --- The Philosopher. --- Theology. --- Theory. --- Thomas Aquinas. --- Thought. --- Tincture (heraldry). --- Transubstantiation. --- Treatise. --- Understanding. --- Upanishads. --- V. --- Volume. --- Wise old man. --- Writing. --- Yale University Library.

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Natural products hold a prominent position in the current discovery and development of drugs and have diverse indications for both human and animal health. Plants, in particular, play a leading role as a source of specialized metabolites with medical effects. Other organisms, such as marine and terrestrial animals and microorganisms, produce very important drug candidate molecules. Specialized metabolites from these varied natural sources can be used directly as bioactive compounds or drug precursors. In addition, due to their broad chemical diversity, they can act as drug prototypes and/or be used as pharmacological tools for different targets. Some examples of natural metabolites that have been developed into useful medical drug are cardiotonic digoxin from Digitalis sp., antimalarial artemisinin from Artemisia annua, anti-cancer taxol from Taxus sp., or podophyllotoxin from Podophyllum peltatum, which served as a synthetic model for the anti-cancer etoposide. The study of natural products is still attracting great scientific attention and their current importance, as a valuable lead for drug discovery, is undebatable. I cordially invite authors to contribute original articles, as well as survey articles, that give the readers of Molecules **MOLECULES NEEDS TO BE ITALICIZED** updated and new perspectives on natural products in drug discovery, including but not limited to natural sources, identification and separation of bioactive phytochemicals, standardization, new biological targets, pre-clinical and clinical trials, pharmacological effects/side effects, and bioassays.

dihydrochalcones --- cytotoxicity-guided --- n/a --- harpagoside --- biotechnology --- synergy --- Imperata cylindrica --- 5?-dimethylchalcone (DMC) --- antioxidant activity --- marine resources --- phenolic derivatives --- secondary metabolites --- antimicrobial agents --- antimicrobial resistance --- metabolomics --- Humulus lupulus --- chromatography --- stereochemistry --- FSE --- cytokines --- cytotoxic activity --- glutamate --- angiogenesis --- traditional medicine --- Ca2+ --- L6 cell --- human colon cancer cell lines --- siphonous green algae --- anti-inflammatory activity --- Phyllanthus chamacristoides --- spectroscopic analysis --- Physcomitrella patens --- Leishmania mexicana mexicana --- dementia --- prenylated phenolic compounds --- T2DM --- HPLC-ESI-microTOF-Q-MS/MS --- Eruca sativa --- Dryopteris fragrans --- chemosystematics --- 2? --- cerebellum --- Cleistocalyx operculatus --- inflammation --- multivariate data analysis --- Phyllanthus orbicularis --- HPLC --- cardiovascular disease --- Kv7 potassium channels --- marine peptides --- proliferation --- sulfated coumarins --- Orobanche s.l. --- phenylpropanoid glycosides --- Harpagophytum procumbens --- sesquiterpenoids --- TRPV1 --- Fideloside --- phenylethanoid glycosides --- Cuba --- molecular network --- NMR --- ketamine --- aging --- GLUT4 --- diabetes --- oxidative stress --- Lamiales --- circular dichroism --- psychosis --- antinociceptive --- immuno-regulation activity --- terpenoids --- NADPH oxidases --- diabetic neuropathy --- spagyric tincture --- H2S --- celastrol --- isolation and quantification --- 4?-dihydroxy-6?-methoxy-3? --- Leea indica --- C-glycoside --- neuropathic pain --- PANC-1 --- glucosinolates --- flavonoids --- bioactivities of natural products --- cardamonin --- isoflavones --- terpenes --- methicillin-resistant Staphylococcus aureus --- malaria --- artemisinin --- natural products --- devil’s claw --- ACE inhibitory peptide --- pPancreatic cancer --- growth inhibitory activity --- mass spectrometry --- flavonoid --- phenolics --- Astragalus boeticus L. --- proanthocyanidins --- opioid --- Trifolium --- Trypanosoma brucei brucei --- acetylated astragalosides --- Fabaceae --- bioactive peptides --- LC-MS --- Dasycladus vermicularis --- Orobanchaceae --- migration --- glucoerucin --- ESI-MS/MS --- cancer --- zebrafish --- antihypertensive --- Bacopa monnieri --- chemical derivatization --- hypertension --- devil's claw

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secret societies --- religious societies --- political societies --- religious secret societies --- high mental development --- primitive culture --- mystic teaching --- mysteries --- astronomy --- dogma --- ancient mysteries --- the Magi --- Magus --- Zoroaster --- initiation --- the myth of Rustam --- the Mithraics --- Mithras --- Thammuz --- Brahmins and Gymnosophists --- India --- Hindoo cosmogony --- Buddhism --- asceticism --- Aum --- the Lingam --- the Lotus --- the Jains --- Egyptian mysteries --- Egyptian civilisation --- Egyptian mythology --- Serapis --- Osiris --- Isis --- Crata Repoa --- Balahate --- Propheta --- the Legend of Isis --- Sabazian mysteries --- mysteries of the Cabiri --- Eleusinian mysteries --- the Thesmophoria --- Grecian mysteries --- Chinese and Japanese mysteries --- Chinese metaphysics --- Buddhism and Christianity --- Lau-Tze --- the Lama --- Mexican and Peruvian mysteries --- American aborigines --- Mexican deities --- human sacrifices --- Druids --- Scandinavian mysteries --- Drottes --- Emanationists --- the Cabbala --- Ezekiel --- Sons of the Widow --- Religion of Love --- Manes --- Manicheism --- Gnosticism --- the Essenes --- sects --- Christian intiations --- myth of Horus --- Christian mysteries --- Pagan rites --- Christian symbols --- Pagan symbols --- Judaism and Gnosticism --- Christianity --- Prometheus --- the Apocalypse --- the Lodge of Wisdom --- Legend of the Mahdi --- Abdallah, the first Pontiff --- Quarmatites --- Fatimite Dynasty --- the Lodge of Cairo --- the Assassins --- Hassan --- the Rosheniah --- the Rosheniah sect --- Bayezid --- the Druses --- Hakem --- Druses and Maronites --- the Ansaireeh or Nuseiriyeh --- the Dervishes --- Shiites and Sunnites --- heretics --- ancient and modern secret societies --- the Circumcellians --- the Albigenses --- the Cathari --- the Waldenses or Vaudois --- Luciferians --- devil-worship --- religion of the Troubadours --- Courts of Love --- chivalry --- Knights the Military Apostles of the Religion of Love --- the Templars --- Commanderies --- Grand Master --- burning of Knights --- James de Molay --- mysteries of the Knights Templars --- the Temple and the Church --- cursing and spitting on the cross --- Baphomet --- the Holy Vehm --- the Beati Paoli --- the Inquisition --- the Auto-da-fé --- the false Nuncio --- mystics --- Alchymists --- astrology --- secret heresy --- alchymy --- tincture --- alchymistic language --- Jacob Böhme --- the Philadelphians --- Emanuel Swedenborg --- the New Jerusalem --- Swedenborgian sects --- Illuminati of Avignon --- Illuminated Theosophists --- philosophic scotch rite --- rite of the Philalethes --- rite of Swedenborg --- universal aurora --- Martinism --- Martinez Paschalis --- Saint-Martin --- Rosicrucians --- Rosicrucian literature --- Rosicrucianism in England --- The Hague Lodge --- the Duke of Saxe-Weimar --- Asiatic brethren --- Melchisedek --- Freemasons --- anti-social societies --- the Thugs --- Thuggism --- the Chauffeurs --- the Burners --- The Garduna --- the Camorra --- Mala Vita --- the mafia --- the Jesuits --- Jesuitism and Freemasonry --- Secreta Monita --- Jesuitic morality --- the Skopzi --- Russian sects --- the legend of Selivanoff --- the Muckers --- Eva von Buttler --- Dionysiac or Bacchic mysteries --- Ishmaelites --- the Canters --- Schönherr's sect --- social regeneration --- Illuminati --- Illuminati in France --- the German Union --- French Workmen's Union --- German Workmen's Unions --- Huntsman's phraseology --- initiation of Cooper --- Guilds --- Kalends Brethren --- Knights of Labour --- ancestry of Hiram Abiff --- Solomon --- the Queen of Sheba --- murder of Hiram --- Masonic customs --- Masonic alphabet --- genuine and spurious Masonry --- ceremonies of initiation --- the raising of Osiris --- the Blazing Star --- the Holy Royal Arch --- Grand Master Architect --- Grand Elect Knight of Kadosh --- Prince of Rose-Croix --- the rites of Misraim and Memphis --- anomalies of the rite of Misraim --- rite of Memphis --- modern Knights Templars --- the Leviticon --- Freemasonry in England and Scotland --- modern Freemasonry --- Freemasonry in France --- Chevalier Ramsay --- the Duke de Chartres --- the Chapter of Clermont and the strict observance --- the relaxed observance --- German Lodges --- rite of Zinzendorf --- the Congress of Wilhelmsbad --- Frederick William III --- Masonry and Napoleonism --- anti-Napoleonic Freemasonry --- the society of 'France Regenerated' --- Freemasonry and Napoleon III --- Freemasonry in Italy --- Illuminati in Italy --- Cagliostro and Egyptian Masonry --- Cagliostro's hydromancy --- androgynous masonry --- androgynous societies --- Knights and Nymphs of the Rose --- German Order of the Rose --- schismatic rites and sects --- Farmassoni --- the Gorgomones --- the Noachites --- Noachidae --- Argonauts --- the Grand Orient and Atheism --- persecutions of Freemasonry --- anti-Masonic publications --- Masonic literature --- the Quatuor Coronati Lodge --- the International --- Anarchists --- political secret societies --- Seal of the Hung League --- the Ko lao Hui --- the Comuneros --- clerical societies --- the Hetairia --- the Hetairia of 1812 --- the Hetairia of 1814 --- Galatis --- Ipsilanti --- Georgakis --- Farmakis --- the Carbonari --- the Vendita --- the Ausonian Republic --- De Witt --- Carbonaro Charter --- Carbonarism and Murat --- Carbonarism and the Bourbons --- Carbonarism and the Church --- Giardiniere --- Guelphic Knights --- Guelphs and Carbonari --- the Latini --- Ciro Annichiarico --- the Decisi --- the Calderari --- the Delphic priesthood --- Egyptian Lodges --- Mazzini and Young Italy --- assassiniation of Rossi --- the Consistorials --- the Roman Catholic Apostolic Congregation --- Sanfedisti --- Napoleonic and anti-Napoleonic societies --- the Rays --- Secret League in Tirol --- the Accoltellatori --- the Acting Company --- Communistic societies --- Polish patriotism --- revolutionary sects --- the Omladika --- the Panslavists --- Young Turkey --- Armenian Society --- the Union of Safety --- the Nihilists --- Nihilism --- Sergei Nechayeff --- Sophia Bardina --- the Party of Terror --- Vera Zassulic --- Nihilist trials --- General Tcherevin --- Colonel Sudelkin --- Gatshina --- Trial of the Fourteen --- the Nihilist Party --- secret press --- Nihilistic literature --- the Mosel Club --- Tugendbund --- the Babis --- Bab --- Babism --- Babi doctrine --- the White-Boys --- Right-Boys and Oak-Boys --- Hearts-of-Steel --- Threshers --- Break-of-Day-Boys --- Defenders --- United Irishmen --- Ribbonmen --- Saint Patrick Boys --- the Orangemen --- Molly Maguires --- Ancient Order of Hibernians --- Fenianism --- Fenian Litany --- General Cluseret --- Phoenix Park Murders --- the National League --- the A B C Friends --- Abelites --- Academy of the Ancients --- Almusseri --- Anonymous Society --- Anti-Masonic Party --- Knights of the Apocalypse --- Areoiti --- Avengers --- Vendicatori --- Belly Paaro --- Californian Society --- Cambridge Secret Society --- Order of Charlottenburg --- Church Masons --- the Congourde --- Duk-Duk --- Egbo Society --- Fraticelli --- the Goats --- Grand Army of the Republic --- Green Island --- Harugari --- African Hemp-smokers --- Heroine of Jericho --- Human Leopards --- Huséanawer --- the Invisibles --- Society of Jehu --- Karpokratians --- Klöbbergöll --- the Order of Knights --- Know-Nothings --- Ku-Klux-Klan --- Kurnai Initiation --- Knights of Liberty --- Knights of the Lion --- the Sleeping Lion --- Ludlam's Cave --- Mad Councillors --- Maharajas --- Mano Negra --- Melanesian societies --- Mumbo-Jumbo --- Odd Fellows --- O-Kee-Pa --- Pantheists --- Patriotic Order Sons of America --- Phi-Beta-Kappa --- the Purrah --- Knights of Pythias --- Rebeccaites --- Order of Redemption --- Red Men --- Society of Universal Regeneration --- Saltpetrers --- Sikh fanatics --- Knights of the Silver Circle --- Sonderbare Gesellen --- Sophisiens --- Star of Bethlehem --- the Thirteen --- Tobaccological Society --- Society of the Turf --- Utopia --- Wahabees