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Familial Alzheimer's disease : molecular genetics and clinical perspectives
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ISBN: 082478068X Year: 1989 Publisher: New York M. Dekker

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Genetic structure and regulation of HIV
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ISBN: 0881678260 Year: 1991 Publisher: New York Raven Press

Hannah's heirs : the quest for the genetic origins of Alzheimer's disease
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ISBN: 0195068092 Year: 1993 Publisher: New York Oxford University Press

Advances in molecular biology and targeted treatment for AIDS : contains articles from the 10th international spring symposium in the health sciences, Washington, May 15-18, 1990
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ISBN: 0306439018 Year: 1991 Publisher: New York London Plenum Press

Prospects for antisense nucleic acid therapy of cancer and AIDS
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ISBN: 0471568805 Year: 1991 Publisher: New York Toronto Singapore Wiley-Liss

Stroke genomics : methods and reviews
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ISSN: 15431894 ISBN: 1280359757 9786610359752 1592598366 1588293335 Year: 2005 Volume: 104 Publisher: Totowa, N.J. : Humana Press,

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Although numerous genomic studies of stroke have examined such factors as stroke inheritance, chromosomal loci of risk, preclinical models of stroke, and differential gene expression of brain injury, repair, and recovery, much work to determine the precise role of gene function in human neurological pathophysiology remains ahead. In Stroke Genomics: Methods and Reviews, leading experts in the field explore the pragmatic application of the tools of genomic and molecular biology research to the treatment of stroke. Providing the reader with cutting-edge reviews of clinical and preclinical genomics, the authors relate changes in gene expression to physiological end points-such as functional imaging paradigms-to produce a more holistic approach in which molecular biology goes hand in hand with stroke pathophysiology. Topics of special interest include stem cell transplantation, gene therapy, clinical gene/gene interaction studies, and cytokine drug discovery. Readily reproducible techniques are provided, along with ancillary methods (imaging, animal models, human genetic study design, and transgenic animal production) that can be effectively applied to gene discovery. The protocols follow the successful Methods in Molecular Biology™ series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and highly practical, Stroke Genomics: Methods and Reviews shows how to successfully design, execute, and interpret preclinical and clinical molecular biological studies of stroke, work that will greatly advance its understanding, as well as rapid development of the next generation of stroke therapeutics.


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Emery's elements of medical genetics
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ISBN: 9780702066856 0702066850 Year: 2017 Publisher: [Philadelphia, PA] : Elsevier,

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"Everything a student needs to know about medical genetics is here in the 15th ediction of this award-winning textbook. Thoroughly updated and revised throughout to map a fast-moving area, the 15th edition continues Emery's enviable reputation for successfully balancing up-to-dateness in a rapidly developing field witha strong basis in practical clinical genetics for medical students." --Back Cover

Celiac disease : methods and protocols
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ISBN: 0896036502 9786610820726 1280820721 1592590829 Year: 2000 Publisher: Totowa, N.J. : Humana Press,

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With the recent development of powerful bioanalytical techniques, research on gluten sensitivity has entered an exciting new phase. In Celiac Disease: Methods and Protocols, Professor Michael N. Marsh, a recognized world authority on this condition, together with a team of other expert laboratory/clinical investigators from around the world present a collection of these state-of-the-art techniques for studying the biology and immunopathology of celiac disease. Both novice and experienced researcher will find in this collection detailed step-by-step methods for cloning lymphocytes, creating gene/peptide libraries, and performing genotyping, linkage, and positional cloning. Also included are techniques for determining the peptide structure of HLA-bound material (tandem mass spectroscopy), computerized morphometry, in situ hybridization, organ culture, and monoclonal AB assays. Comprehensive and cutting-edge, Celiac Disease: Methods and Protocols provides all experimental and clinical investigators with the essential core of readily reproducible methods necessary for successful work on celiac disease today.

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