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Medische genetica
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ISBN: 9063484534 Year: 1985 Publisher: Utrecht Bunge

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Medical genetics at a glance
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ISBN: 0632063726 Year: 2003 Publisher: Oxford Blackwell

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Studie naar de transcriptionele regulatie van het SOST gen: genereren van luciferase reportergen constructen
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Year: 2006 Publisher: Hoboken KdG.IWT

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Onderzoek naar de identificatie van genen betrokken bij de regulatie van botdichtheid
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Year: 2008 Publisher: Hoboken KDG.IWT

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Decoding the language of genetics
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ISBN: 9781621820925 1621820920 Year: 2015 Publisher: Cold Spring Harbor, N.Y. Cold Spring Harbor Laboratory Press

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"In this book, the distinguished geneticist David Botstein offers help and advice to scientists and physicians daunted by the arcane technical terms that flourish in his discipline. As knowledge of gene function has progressed over the past century, it has acquired a vocabulary of specialized, sometimes confusing, terms to explain some of its fundamental principles; how traits and diseases are inherited; how genes are organized and regulated in the genome; and how the genetic code is read and translated by cells. These terms often prevent the less expert from fully understanding the concepts that underlie the power of genetic studies. This is not just a theoretical handicap. As more and more individuals learn about their genomes, the information these sequences contain cannot be understood or explained without reference to the basic ideas of genetics. Botstein draws on his long experience as a teacher and pioneering scientist to explain and illuminate what many genetic terms mean and how they entered common usage. To colleagues in the field, his message is one of encouragement, to "make our work more generally accessible by modernizing, clarifying, and simplifying the language we use and teach." "This is a book about the conceptual language of genetics. There is a need for special words and terms to deal with some of the essential abstractions in genetics; these are the focus of this book. It is intended to help readers with diverse interests and experience to think about genetic analysis in a more sophisticated and creative way"


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Computational Genetics and Genomics : Tools for Understanding Disease
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ISBN: 9781592599301 Year: 2005 Publisher: Totowa NJ Humana Press

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Despite ever-increasing investments in genetic research, the translation of genetic discoveries into new therapies has been a slow process. In Computational Genetics and Genomics: Tools for Understanding Disease, well-recognized computational geneticists review and assess both currently available and developing tools for the rapid identification of the genetic basis for susceptibility to disease. The authors introduce a new computational approach that makes it possible to identify the genetic basis for differences in physiological or pathological responses among inbred mouse strains, thus facilitating more rapid genetic discovery. The focus is on the haplotype-based computational genetic analysis method and its application to inbred mouse strains. Reviewing murine models of asthma, lung disease, osteoporosis, and substance abuse, the contributors provide an overview of available mouse models, what has been learned from them, and which new models must be developed to advance our understanding of these diseases. They also describe how genetic analysis of human populations has yielded information on the genetic basis for susceptibility to asthma and other inflammatory diseases. Authoritative and path-breaking, Computational Genetics and Genomics: Tools for Understanding Disease surveys and assesses both currently available and powerful new computational genetic mapping methods that can be used to quickly analyze genetic models of biomedically important traits. This information provides a basis for uncovering the genetic factors regulating human disease-related traits.


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DNA Methylation: Basic Mechanisms
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ISBN: 9783540313908 Year: 2006 Publisher: Berlin Heidelberg Springer Berlin Heidelberg

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DNA Methylation: Development, Genetic Disease and Cancer
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ISBN: 9783540311812 Year: 2006 Publisher: Berlin Heidelberg Springer Berlin Heidelberg

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Genetic Control of Neuronal Migrations in Human Cortical Development
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ISBN: 9783540366898 Year: 2007 Publisher: Berlin Heidelberg Springer Berlin Heidelberg

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RNA Interference
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ISBN: 9783540751571 Year: 2008 Publisher: Berlin Heidelberg Springer Berlin Heidelberg

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