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Enfants cobayes : cancer de l'enfant : enquête sur les dérives d'un système.
Authors: ---
ISBN: 284186166X Year: 2002 Publisher: Paris Michalon,

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Abstract

Malgré les progrès thérapeutiques importants réalisés depuis vingt ans, des centaines d'enfants, chaque année, meurent du cancer. Les auteurs se sont penchés sur le fonctionnement actuel des services de cancérologie de l'enfant. Les essais thérapeutiques " randomisés ", qui consistent à donner aux malades un traitement tiré au sort, y sont devenus une règle indiscutable. Certains, pourtant, refusent depuis plus de vingt ans de suivre aveuglément cette méthode qui privilégie la recherche de groupe au détriment d'une médecine plus humaine adaptée aux besoins de chaque enfant. Pourquoi leurs médecins ont-ils un jour décidé d'arrêter les traitements de Lucie ou d'Anaïs quand d'autres ont fait renaître l'espoir ? Pourquoi n'ont-ils pas jugé nécessaire d'informer précisément les parents sur la nature des traitements, malgré l'obligation de " consentement éclairé " de la famille imposé par la loi ? Pourquoi leur a-t-on caché l'existence d'une approche thérapeutique différente ? Nos enfants servent-ils de " cobayes " ? Une enquête qui dénonce les dérives d'un système et nous plonge dans une réalité quotidienne insupportable dont les principales victimes ignorent tout.

Protecting study volunteers in research : a manual for investigate sites.
Authors: ---
ISBN: 1930624360 Year: 2002 Publisher: Boston Thomson,

The abuse of man : an illustrated history of dubious medical experimentation.
Author:
ISBN: 189335721X Year: 2003 Publisher: New York Ardor Scribendi,

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In this work, Wolfgang Weyers, a physician himself, cuts a swath, profoundly, through the history of unethical experiments on humans, from the first intentional innoculation of a patient with syphilis and gonorrhea in England of the late 18th century through the infamous Tuskegee Study...to the exploitation of orphans and prisoners as human guinea pigs...The scope of Weyers' erudition includes the East, as well as the West, and spares none of import who engaged in these unconscionable practices.

Human experimentation and research.
Authors: ---
ISBN: 0754622266 Year: 2003 Publisher: Aldershot Ashgate,

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Human experimentation is essential to advance scientific knowledge and thereby improve the longevity and quality of human lives. This text covers some of the legal, technical, ethical and moral problems raised by human experimentation.

Volunteers in research and testing.

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This text discusses the use of volunteers, either healthy or undergoing treatment, in the research and testing of medicinal and non-medicinal products. The extent to which the improved use of such volunteers could reduce the need for animal tests is [...]


Book
La protection des sujets de recherches notamment dans le domaine biomédical.
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ISBN: 3727201878 Year: 1993 Volume: 543 Publisher: Berne Staempfli,

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La réglementation des recherches sur l'homme subit actuellement de profondes mutations tant au niveau national qu'international. Ce livre a pour ambition de décrire fidèlement ce qui est, tout en jetant les bases d'une nécessaire amélioration de la protection des sujets de recherche en droit suisse. Il offre aussi une solide base de réflexion à tous ceux qui sont amenés à jouer un rôle dans ce domaine.

Case studies in biomedical research ethics
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ISBN: 0262134373 0262632861 Year: 2004 Publisher: Cambridge, Mass. MIT

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An overview of the key debates in biomedical research ethics, presented through a wide-ranging selection of 149 case studies. This textbook for instruction in biomedical research ethics can also serve as a valuable reference for professionals in the field of bioethics. The 149 cases included in the book are grouped in nine chapters, each of which covers a key area of debate in the field. Some of the case studies are classics, including the famous cases of the Tuskegee Syphilis Study (in which subjects with syphilis were not given treatment) and the Willowbrook hepatitis studies (in which institutionalized subjects were intentionally exposed to hepatitis). Others focus on such current issues as human embryonic stem cell research, cloning by somatic nuclear transfer, and the design and function of institutional review boards. Each chapter begins with a brief introduction that places the issues raised in context; this is followed by a number of cases (each of which is no more than a few pages). Study questions meant to encourage further discussion follow each case. After an introductory discussion of the history and tenets of ethics in medical research, the book's chapters cover the topics of oversight and study design; informed consent; the selection of subjects; conflicts of interest; the social effects of research; embryos, fetuses, and children; genetic research; the use of animals; and authorship and publication. Following these chapters are appendixes with the texts of the Nuremburg Code and the Declaration of Helsinki, two key documents in the establishment of bioethical standards for research.


Book
Recherche biomédicale et populations vulnérables.
Authors: --- --- --- --- --- et al.
ISSN: 12753653 ISBN: 2296014615 9782296014619 Year: 2006 Publisher: Paris L'Harmattan,

The ethics of research involving human subjects : facing the 21st century.
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ISBN: 1555720366 Year: 1996 Publisher: Frederick University publishing group,

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A collection of essays discussing the complex issues of research involving human participants, including research ethics and regulations, conflicts of interest, cross-cultural research, and critical issues in specialized areas of research, such pediatric and genome research. As its primary objective, this book seeks to make sense of an almost overwhelming body of literature & regulation on research ethics.A collection of essays discussing the complex issues of research involving human participants, including research ethics and regulations, conflicts of interest, cross-cultural research, and critical issues in specialized areas of research, such pediatric and genome research.

Responsible research : a systems approach to protecting research participants
Authors: --- ---
ISBN: 0309084881 9786610209392 1280209399 030950046X Year: 2003 Publisher: Washington, D.C. : National Academies Press,

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Outlines an approach to ensure the protection of participants through the establishment of effective Human Research Participant Protection Programs (HRPPP). Topics covered in this book include improved research review processes, recognition and integration of research participants contributions to the system, and vigilant maintenance of HRPPP performance. When 18-year-old Jesse Gelsinger died in a gene transfer study at the University of Pennsylvania, the national spotlight focused on the procedures used to ensure research participants safety and their capacity to safeguard the well-being of those who volunteer for research studies. "Responsible Research" outlines a three-pronged approach to ensure the protection of every participant through the establishment of effective Human Research Participant Protection Programs (HRPPPs). The approach includes: improved research review processes; recognition and integration of research participants contributions to the system, and vigilant maintenance of HRPPP performance. Issues addressed in the book include the need for in-depth, complimentary reviews of science, ethics, and conflict of interest reviews; desired qualifications for investigators and reviewers; the process of informed consent; federal and institutional oversight; and the role of accreditation. Recommendations for areas of key interest include suggestions for legislative approaches, compensation for research-related injury, and the refocusing of the mission of institutional review boards. "Responsible Research" will be important to anyone interested in the issues that are relevant to the practice of using human subjects as research participants, but especially so to policy makers, research administrators, investigators, and research sponsors but also including volunteers who may agree to serve as research participants.

Keywords

MEDICAL --- Research --- Ethics --- Human Rights --- Epidemiologic Study Characteristics as Topic --- Jurisprudence --- Professional-Patient Relations --- Investigative Techniques --- Social Control Policies --- Biomedical Research --- Accident Prevention --- Persons --- Social Control, Formal --- Professional Staff Committees --- Ethics Committees --- Therapeutics --- Health Care Quality, Access, and Evaluation --- Policy --- Health Care Economics and Organizations --- Named Groups --- Humanities --- Interpersonal Relations --- Accidents --- Sociology --- Quality Assurance, Health Care --- Health Care Evaluation Mechanisms --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Science --- Professional Practice --- Quality of Health Care --- Health Care --- Social Sciences --- Public Health --- Psychology, Social --- Natural Science Disciplines --- Disciplines and Occupations --- Anthropology, Education, Sociology and Social Phenomena --- Organization and Administration --- Environment and Public Health --- Behavior and Behavior Mechanisms --- Psychiatry and Psychology --- Health Services Administration --- Human Experimentation --- Safety --- Government Regulation --- Public Policy --- Conflict of Interest --- Ethics Committees, Research --- Informed Consent --- Clinical Protocols --- Researcher-Subject Relations --- Ethical Review --- Patient Rights --- Clinical Trials Data Monitoring Committees --- Research Subjects --- experiment, experimenteel onderzoek (mensen) --- ethiek (ethische aspecten) --- geïnformeerde vrijwillige toestemming (instemming) --- proefpersonen --- Verenigde Staten --- belangenconflict --- expérimentation sur la personne humaine (chez l'humain) --- ethique (aspects ethiques) --- consentement libre et éclairé --- sujets (participants) d'expérimentation --- Etats Unis --- conflit d'intérêt --- Human experimentation in medicine --- Medical ethics. --- Medical protocols. --- Patients --- Moral and ethical aspects. --- Legal status, laws, etc. --- Patients' rights --- Clinical algorithms --- Clinical protocols --- Patient care plans --- Plans for patient care --- Protocols in medicine --- Biomedical ethics --- Clinical ethics --- Ethics, Medical --- Health care ethics --- Medical care --- Medicine --- Moral and ethical aspects --- Clinical medicine --- Medical records --- Bioethics --- Professional ethics --- Nursing ethics --- Social medicine --- Medical ethics --- Medical protocols --- Legal status, laws, etc

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